Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Jamil Azzi"'
Circulating B Cells, Plasma Cells, and Treg Associate with ANCA Levels in ANCA-associated Vasculitis
Autor:
Joaquin Manrique, Emilie Chan, Susan Hartzell, Samuel Mon-Wei Yu, Chiara Cantarelli, Loreto F. Fernandez, María F. Slon, Carolina Purroy, Ioannis Tassiulas, Jamil Azzi, Leonardo V. Riella, Umberto Maggiore, Paolo Cravedi
Publikováno v:
Kidney International Reports, Vol 6, Iss 2, Pp 496-500 (2021)
Externí odkaz:
https://doaj.org/article/4918488242824c22876bb643fbf183ff
Autor:
Thiago J. Borges, Naoka Murakami, Isadora T. Lape, Rodrigo B. Gassen, Kaifeng Liu, Songjie Cai, Joe Daccache, Kassem Safa, Tetsunosuke Shimizu, Shunsuke Ohori, Alison M. Paterson, Paolo Cravedi, Jamil Azzi, Peter T. Sage, Arlene H. Sharpe, Xian C. Li, Leonardo V. Riella
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
The programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway is a potent inhibitory pathway involved in immune regulation and is a potential therapeutic target in transplantation. In this study, we show that overexpression of PD-1 on T cells
Externí odkaz:
https://doaj.org/article/e5c5cdd28c4848f786e0494cfcee2014
Autor:
Jewel Imani, Kaifeng Liu, Ye Cui, Jean-Pierre Assaker, Junwen Han, Auyon J. Ghosh, Julie Ng, Shikshya Shrestha, Anthony M. Lamattina, Pierce H. Louis, Anne Hentschel, Anthony J. Esposito, Ivan O. Rosas, Xiaoli Liu, Mark A. Perrella, Jamil Azzi, Gary Visner, Souheil El-Chemaly
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Lung allograft rejection results in the accumulation of low–molecular weight hyaluronic acid (LMW-HA), which further propagates inflammation and tissue injury. We have previously shown that therapeutic lymphangiogenesis in a murine model of lung al
Externí odkaz:
https://doaj.org/article/3872cafd531f498db289be7c44439e4d
Autor:
Jing Zhao, Liwei Jiang, Mayuko Uehara, Naima Banouni, Basmah S. Al Dulaijan, Jamil Azzi, Takaharu Ichimura, Xiaofei Li, Petr Jarolim, Paolo Fiorina, Stefan G. Tullius, Joren C. Madsen, Vivek Kasinath, Reza Abdi
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
Heart transplantation is the optimal therapy for patients with end-stage heart disease, but its long-term outcome remains inadequate. Recent studies have highlighted the importance of the melanocortin receptors (MCRs) in inflammation, but how MCRs re
Externí odkaz:
https://doaj.org/article/c5e7fbcbd733432da7013381413421fa
Autor:
Orhan Efe, Martina M. McGrath, Frances Y. Hu, Venkat Ramanathan, Ronald T. Cotton, Joel T. Adler, Jamil Azzi
Publikováno v:
Kidney Medicine, Vol 3, Iss 2, Pp 307-308 (2021)
Externí odkaz:
https://doaj.org/article/a122ddecdf79422489a027013b8ec710
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease (COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed among the elderly could explain, at least in part, the age gradient in leth
Externí odkaz:
https://doaj.org/article/38aac4f66eec4f049c00d84007076676
Autor:
Tahir Abdulrehman, Shahnaz Qadri, Sini Skariah, Ali Sultan, Said Mansour, Jamil Azzi, Yousef Haik
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231276 (2020)
OBJECTIVES:Alloyed metallic nanoparticles of silver and copper are effective against intracellular infection. However, systemic toxicity may arise due to the non-specific delivery of the nanoparticles. In addressing the issue, this study deals with t
Externí odkaz:
https://doaj.org/article/d671a932e7f843058651442107591a4e
Autor:
Thiago J. Borges, Naoka Murakami, Felipe D. Machado, Ayesha Murshid, Benjamin J. Lang, Rafael L. Lopes, Laura M. Bellan, Mayuko Uehara, Krist H. Antunes, Maria José Pérez-Saéz, Gabriel Birrane, Priscila Vianna, João Ismael B. Gonçalves, Rafael F. Zanin, Jamil Azzi, Reza Abdi, Satoshi Ishido, Jeoung-Sook Shin, Ana Paula D. Souza, Stuart K. Calderwood, Leonardo V. Riella, Cristina Bonorino
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Donor-derived dendritic cells (do-DC) in the graft can contribute to the induction of alloimmunity and tissue rejection, but how do-DC can be targeted for improving graft survival is unclear. Here the authors show that reducing MHC-II expression on d
Externí odkaz:
https://doaj.org/article/ead005caa3954154a96d660f0fad15fc
Autor:
Ruda de Luna Almeida Santos, Lin Bai, Pradeep K. Singh, Naoka Murakami, Hao Fan, Wenhu Zhan, Yingrong Zhu, Xiuju Jiang, Kaiming Zhang, Jean Pierre Assker, Carl F. Nathan, Huilin Li, Jamil Azzi, Gang Lin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Immunoproteasome selective inhibitors might lead to less toxic drugs for treatment of multiple myeloma and graft rejection. Here, the authors develop immunoproteasome specific asparagine-ethylenediamine (AsnEDA)-based inhibitory compounds, demonstrat
Externí odkaz:
https://doaj.org/article/aaef590b4c434dd3a24ff936b3177a69
Autor:
Mayuko Uehara, Martina M. McGrath, Shunsuke Ohori, Zhabiz Solhjou, Naima Banouni, Sujit Routray, Catherine Evans, Jonathan P. DiNitto, Abdallah Elkhal, Laurence A. Turka, Terry B. Strom, Stefan G. Tullius, David G. Winkler, Jamil Azzi, Reza Abdi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Phosphatidylinositol-3-kinases (PI3K) γ and δ are key regulators of T cell signaling. Here the author show, using mouse heart allograft transplantation models, that PI3Kγ or PI3Kδ deficiency prolongs graft survival, but selective inhibition of PI
Externí odkaz:
https://doaj.org/article/818831b33b2247b79607d6e3430cab97