Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jamil Aarbiou"'
Autor:
Miranda de Graaf, Sander Herfst, Jamil Aarbiou, Peter C Burgers, Fatiha Zaaraoui-Boutahar, Maarten Bijl, Wilfred van Ijcken, Eefje J A Schrauwen, Albert D M E Osterhaus, Theo M Luider, Bob J Scholte, Ron A M Fouchier, Arno C Andeweg
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58572 (2013)
Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compa
Externí odkaz:
https://doaj.org/article/228aa1f0d2004a7998ff55e0cca15a17
Publikováno v:
Cancer Research. 80:3232-3232
Chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered T cells are part of a big wave of immunotherapies showing great promise in cancer clinical trials. With the first T cell based therapies targeting hematological malignances now appr
Autor:
Miranda van der Ham, Laure Grandmoursel, Armin Maier, Julia Schüler, Anne-Marie Zuurmond, Jamil Aarbiou, Ian D. Waddell, Geraldine Servant, Lieke Geerts, Jeroen DeGroot, Marijn Vlaming
Publikováno v:
Molecular Cancer Therapeutics. 18:C021-C021
New targets for cancer treatment frequently emerge in literature, but the thorough target validation required to consider these targets for a drug discovery program is often lacking. In pharmacological or genetic perturbation studies using complex bi
Autor:
Jeroen DeGroot, Britt Sotthewes, Jeska K de Vries-Bouwstra, Kejie Li, Patrick Cullen, Joanne L. Viney, Agnes Gardet, Jamil Aarbiou, Marc Cheung, S.N. Andersen, Tom W J Huizinga, Timothy S. Zheng, Ellen Cahir-McFarland, David F. Fischer, Annemarie L. Dorjée, Loubna Chadli
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 9
Systemic sclerosis (SSc or scleroderma) is an auto-immune disease characterized by skin fibrosis. While primary cells from patients are considered as a unique resource to better understand human disease biology, the effect of in vitro culture on thes
Autor:
Soledad R. Ordonez, Richard A.J. Janssen, Gimano D. Amatngalim, Jamil Aarbiou, Almira Henic, Annemarie N. Lekkerkerker, Maria E. Fuentes, Pieter S. Hiemstra, Renate M. Verhoosel, Jasmijn A. Schrumpf, Henk P. Haagsman, Sriram Sridhar, Esther Dronkers
Publikováno v:
Journal of Innate Immunity, 9(4), 359-374
Antimicrobial proteins and peptides (AMPs) are a central component of the antibacterial activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung defense contributes to an increased susceptibility to microbial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4cf31e0327106f6d77a04d2a1c2a54
https://hdl.handle.net/1887/115623
https://hdl.handle.net/1887/115623
Autor:
Varshna S. Goelela, Oliver Distler, A. Dorjee, Michael L. Whitfield, René E. M. Toes, Tobias Messemaker, Loubna Chadli, Jeroen de Groot, Harald Mikkers, Tom W J Huizinga, S.N. Andersen, Guoshuai Cai, Fina A S Kurreeman, Maaike Boonstra, Jamil Aarbiou, Jeska K de Vries-Bouwstra, Zhenghui Li
Publikováno v:
Poster Presentations.
Background Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and multiple organs of which pathogenesis is poorly understood. Here we studied differentially expressed coding and non-coding genes in relation to SSc pat
Autor:
Hailiang Mei, Fina A S Kurreeman, René E. M. Toes, Varshna S. Goelela, Jeroen DeGroot, Guoshuai Cai, Jamil Aarbiou, S.N. Andersen, Loubna Chadli, Harmen H.M. Draisma, Jeska K de Vries-Bouwstra, Peter van ‘t Hof, Robert W. Simms, M. Boonstra, Oliver Distler, Tom W J Huizinga, Michael E. Johnson, Harald Mikkers, Michael L. Whitfield, Tobias Messemaker, Nicole M. Orzechowski, Annemarie L. Dorjée
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, 138(4), 826-835
Journal of Investigative Dermatology, 138(4), 826-835
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and multiple organs of which the pathogenesis is poorly understood. Here we studied differentially expressed coding and non-coding genes in relation to SSc pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8cf541a15a9aed2dc2eb13d732b297
http://hdl.handle.net/1887/115736
http://hdl.handle.net/1887/115736
Autor:
Stefano Castellani, Pieter S. Hiemstra, Anna Diana, Pascal van der Wegen, Francesca Tilesi, Guelnihal Yueksekdag, Joseph Rosenecker, Jamil Aarbiou, Bob J. Scholte, Ruvalic M. Buijs-Offerman, Elena Copreni, Fiorentina Ascenzioni, Piera Assunta Fradiani, Annalucia Carbone, Massimo Conese
Publikováno v:
The Journal of Gene Medicine. 14:733-745
BACKGROUND Epithelial sodium channel (ENaC) hyperactivity has been implicated in the pathogenesis of cystic fibrosis (CF) by dysregulation of fluid and electrolytes in the airways. In the present study, we show proof-of-principle for ENaC inhibition
Autor:
Bob J. Scholte, Lhousseine Touqui, Martina Wilke, William H. Colledge, Jamil Aarbiou, Hugo R. de Jonge, Ruvalic M. Buijs-Offerman, Alice G. M. Bot, David N. Sheppard, Huub Jorna
Publikováno v:
Journal of Cystic Fibrosis, 10, S152-S171. Elsevier
Genetically modified mice have been studied for more than fifteen years as models of cystic fibrosis (CF). The large amount of experimental data generated illuminates the complex multi-organ pathology of CF and raises new questions relevant to human
Autor:
Mark K. Titulaer, Ruvalic M. Buijs-Offerman, Martina Wilke, Jamil Aarbiou, Bob J. Scholte, Thomas Schettgen, Thomas Kraus, Theo M. Luider, Nuno Charro, Deborah Penque, Peter Burgers, Isabel Carvalho-Oliveira
Publikováno v:
Journal of Proteome Research, 8(7), 3606-3616. American Chemical Society
Combined results from laser capture microdissection of mouse airway epithelial cells followed by high power (MALDI-FTICR) MS, and fluorescent two-dimensional gel elctrophoresis (2D-DIGE) of the whole lung, allowed us to identify proteins differential