Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jamie R. Schoenborn"'
Autor:
Jing Xia, Colm Morrissey, Lisha G. Brown, Sandy Larson, Robert L. Vessella, Jamie R. Schoenborn, Xiaoyu Qu, Yu Wu, Paul H. Lange, Min Fang, Peter S. Nelson
Publikováno v:
The Journal of Molecular Diagnostics. 18:131-143
Circulating tumor cells and disseminated tumor cells (DTCs) are of great interest because they provide a minimally invasive window for assessing aspects of cancer biology, including tumor heterogeneity, a means to discover biomarkers of disease behav
Publikováno v:
Clinical Cancer Research. 19:4058-4066
The remarkable variation in prostate cancer clinical behavior represents an opportunity to identify and understand molecular features that can be used to stratify patients into clinical subgroups for more precise outcome prediction and treatment sele
Publikováno v:
Science Signaling. 4
The Src family kinase Lck is crucial for the initiation of TCR signaling. The activity of Lck is tightly controlled to prevent erroneous immune activation, yet it enables rapid cellular responses over a range of sensitivities to antigens. Here, in ex
Publikováno v:
Advances in immunology. 96
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produce
Publikováno v:
Protocol Exchange.
Autor:
Jamie R, Schoenborn, Michael O, Dorschner, Masayuki, Sekimata, Deanna M, Santer, Maria, Shnyreva, David R, Fitzpatrick, John A, Stamatoyannopoulos, John A, Stamatoyonnapoulos, Christopher B, Wilson
Unlike the well defined T helper type 2 cytokine locus, little is known about the regulatory elements that govern the expression of Ifng, which encodes the 'signature' T helper type 1 cytokine interferon-gamma. Here our evolutionary analysis showed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850181d0ef94af98604a7fd554fe3ebd
https://europepmc.org/articles/PMC2144744/
https://europepmc.org/articles/PMC2144744/
Publikováno v:
Advances in Immunology ISBN: 9780123737090
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71cbb9a4f5b34d9e9c030c2bd65b5e0d
https://doi.org/10.1016/s0065-2776(07)96002-2
https://doi.org/10.1016/s0065-2776(07)96002-2
Autor:
Min Fang, Colm Morrissey, Robert L. Vessella, Peter S. Nelson, Sandy Larson, Jing Xia, Jamie R. Schoenborn, Paul H. Lange, Lisha Brown
Publikováno v:
Cancer Research. 72:B31-B31
Objective: Dissemination of prostate cancer tumor cells remains a critical challenge in understanding disease progression and effective long-term treatment of patients. Disseminated tumor cells (DTCs) from bone marrow are resistant to chemotherapy an
Autor:
Jamie R. Schoenborn, Min Fang, Melissa Chiu, Grace Randhawa, Kathleen Kroeger, Cynthia Friedman, Siobhan O'Hara-Larrivee, Scott McElhone
Publikováno v:
Cancer Genetics. 204:469
Publikováno v:
The Journal of Immunology. 182:35.4-35.4
Src family kinases are normally inhibited by phosphorylation of their C-terminal tail by the tyrosine kinase Csk, and are positively regulated by the phosphatase CD45 and by receptor stimulation. Attempts to study the role of Csk in T cell receptor (