Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jamie Peters"'
Autor:
Giuseppe Giannotti, Francesca Mottarlini, Jasper A. Heinsbroek, Mitchel R. Mandel, Morgan H. James, Jamie Peters
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract As opioid-related fatalities continue to rise, the need for novel opioid use disorder (OUD) treatments could not be more urgent. Two separate hypothalamic neuropeptide systems have shown promise in preclinical OUD models. The oxytocin system
Externí odkaz:
https://doaj.org/article/747f17c9d8044e4cacd8892d51c9f269
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/c56a4189944d441cbdaa95522972dd74
Autor:
Jasper A. Heinsbroek, Giuseppe Giannotti, Mitchel R. Mandel, Megan Josey, Gary Aston-Jones, Morgan H. James, Jamie Peters
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The neural circuits underlying rewarding effects of drugs of abuse and natural rewards are not fully understood. Here the authors investigate the role of the infralimbic cortex to nucleus accumbens shell pathway during heroin or food choice in rats.
Externí odkaz:
https://doaj.org/article/637a7523d5dc4b48b8397126271ff87f
Autor:
Giuseppe Giannotti, Sheng Gong, Nicholas Fayette, Jasper A. Heinsbroek, James E. Orfila, Paco S. Herson, Christopher P. Ford, Jamie Peters
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109605- (2021)
Summary: Here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (PVT) to nucleus accumbens (NAc) pathway in aversion and heroin relapse in two different heroin self-administration models in rats. I
Externí odkaz:
https://doaj.org/article/871e82e44d15409d9fd6859a44b79a3a
Autor:
Jamie Peters, David E Olson
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Addiction is best described as a disorder of maladaptive neuroplasticity involving the simultaneous strengthening of reward circuitry that drives compulsive drug seeking and weakening of circuits involved in executive control over harmful behaviors.
Externí odkaz:
https://doaj.org/article/03f0e055cee3443aa8d1086ae82ace5e
Detrimental Effects of a Retrieval-Extinction Procedure on Nicotine Seeking, but Not Cocaine Seeking
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Retrieval-extinction memory reactivation procedures have been used to prevent the return of learned fear and drug seeking in preclinical models. These procedures first reactivate the original memory with a brief cue exposure (i.e., retrieval) session
Externí odkaz:
https://doaj.org/article/eba3071b5ba84c5593ad4721110fd4e2
Autor:
Victoria N, Chang, Jamie, Peters
Publikováno v:
Neuropharmacology. 226:109407
As the opioid epidemic presents an ever-expanding public health threat, there is a growing need to identify effective new treatments for opioid use disorder (OUD). OUD is characterized by a behavioral misallocation in choice behavior between opioids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821e15e49285821e42e0775d1ea2e40f
https://doi.org/10.1016/j.neuropharm.2022.109407
https://doi.org/10.1016/j.neuropharm.2022.109407
Publikováno v:
Heinsbroek, J A, De Vries, T J & Peters, J 2021, ' Glutamatergic systems and memory mechanisms underlying opioid addiction ', Cold Spring Harbor perspectives in medicine, vol. 11, no. 3, a039602, pp. 1-31 . https://doi.org/10.1101/cshperspect.a039602
Cold Spring Harb Perspect Med
Cold Spring Harbor perspectives in medicine, 11(3):a039602, 1-31. Cold Spring Harbor Laboratory Press
Heinsbroek, J A, de Vries, T J & Peters, J 2021, ' Glutamatergic systems and memory mechanisms underlying opioid addiction ', Cold Spring Harbor perspectives in medicine, vol. 11, no. 3, a039602, pp. 1-31 . https://doi.org/10.1101/cshperspect.a039602
Cold Spring Harb Perspect Med
Cold Spring Harbor perspectives in medicine, 11(3):a039602, 1-31. Cold Spring Harbor Laboratory Press
Heinsbroek, J A, de Vries, T J & Peters, J 2021, ' Glutamatergic systems and memory mechanisms underlying opioid addiction ', Cold Spring Harbor perspectives in medicine, vol. 11, no. 3, a039602, pp. 1-31 . https://doi.org/10.1101/cshperspect.a039602
Glutamate is the main excitatory neurotransmitter in the brain and is of critical importance for the synaptic and circuit mechanisms that underlie opioid addiction. Opioid memories formed over the course of repeated drug use and withdrawal can become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27ea02f3becb3ebdb68654ca3f9bd0d
http://www.scopus.com/inward/record.url?scp=85100578649&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85100578649&partnerID=8YFLogxK
Autor:
Lavinia Ferrante di Ruffano, Isobel M Harris, Zhivko Zhelev, Clare Davenport, Sue Mallett, Jamie Peters, Yemisi Takwoingi, Jon Deeks, Chris Hyde
Objectives To identify which international health technology assessment (HTA) agencies are undertaking evaluations of medical tests, summarize commonalities and differences in methodological approach, and highlight examples of good practice. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9a55ab26701d97c01a01ee90ae077a
https://doi.org/10.1101/2022.05.17.22275215
https://doi.org/10.1101/2022.05.17.22275215
Autor:
Jamie Peters
Publikováno v:
Nature Communications
Activity in numerous brain regions drives heroin seeking, but no circuits that limit heroin seeking have been identified. Furthermore, the neural circuits controlling opioid choice are unknown. In this study, we examined the role of the infralimbic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fa06921530420dded8d4bb8ff0f76a
https://pubmed.ncbi.nlm.nih.gov/34373454
https://pubmed.ncbi.nlm.nih.gov/34373454