Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jamie M Goodson"'
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
EExposure to air pollution has long been known to trigger cardiovascular events, primarily through activation of local and systemic inflammatory pathways that affect the vasculature. Detrimental effects of air pollution exposure on heart failure and
Externí odkaz:
https://doaj.org/article/b390671d235e42c5841dee1ac7b2ee33
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background Developmental exposure to particulate matter air pollution is harmful to cardiovascular health, but the mechanisms by which this exposure mediates susceptibility to heart disease is poorly understood. We have previously shown, in
Externí odkaz:
https://doaj.org/article/6c8109b65d684ba7bcfacd9aa3c8493e
Autor:
Jason W. Miklas, Shiri Levy, Peter Hofsteen, Diego Ic Mex, Elisa Clark, Jeanot Muster, Aaron M. Robitaille, Gargi Sivaram, Lauren Abell, Jamie M. Goodson, Inez Pranoto, Anup Madan, Michael T. Chin, Rong Tian, Charles E. Murry, Randall T. Moon, Yuliang Wang, Hannele Ruohola-Baker
Publikováno v:
iScience
iScience, Vol 25, Iss 1, Pp 103574-(2022)
iScience, Vol 25, Iss 1, Pp 103574-(2022)
Summary Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can regenerate their hearts via cardiomyocyte d
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-12 (2019)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Developmental exposure to particulate matter air pollution is harmful to cardiovascular health, but the mechanisms by which this exposure mediates susceptibility to heart disease is poorly understood. We have previously shown, in a mouse m
Autor:
Chad S. Weldy, Wei-Ming Chien, Michael T. Chin, James W. MacDonald, Yonggang Liu, Jamie M. Goodson, Theo K. Bammler
In utero exposure to diesel exhaust air pollution has been associated with increased adult susceptibility to heart failure in mice, but the mechanisms by which this exposure promotes susceptibility to heart failure are poorly understood. To identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ea43605d6dd009e06642f6b8d1f2ed
https://europepmc.org/articles/PMC5636696/
https://europepmc.org/articles/PMC5636696/
Publikováno v:
Circulation Research. 121
Epidemiological studies have revealed that exposure to particulate matter air pollution is harmful to cardiovascular health. Recent studies have shown that exposure during development can affect fetal outcomes through alterations in blood pressure an
Autor:
Pei-Tzu Yang, Jamie N. Anastas, Michi M. Shinohara, Anja K. Bosserhoff, Rachel A. Toroni, Andy J. Chien, Jamie M. Goodson, Randall T. Moon
Publikováno v:
EMBO Molecular Medicine
Elevated levels of nuclear β-catenin are associated with higher rates of survival in patients with melanoma, raising questions as to how ß-catenin is regulated in this context. In the present study, we investigated the formal possibility that the s
Autor:
Jennifer Potter, Allison M. Adams, Kathryn C. Davidson, Circe E. McDonald, Randall T. Moon, Travis L. Biechele, Russell J. Taylor, Jamie M. Goodson, Jason D. Berndt
Publikováno v:
Proceedings of the National Academy of Sciences. 109:4485-4490
Signal transduction pathways play diverse, context-dependent roles in vertebrate development. In studies of human embryonic stem cells (hESCs), conflicting reports claim Wnt/β-catenin signaling promotes either self-renewal or differentiation. We use
Autor:
Ryan J. Nathe, Randall T. Moon, Philip J. Horner, Jamie M. Goodson, Nghi K. Nguyen, Bryan D. White, Don O. Maris
Publikováno v:
Stem Cells. 28:297-307
Wnt/β-catenin signaling can influence the proliferation and differentiation of progenitor populations in the hippocampus and subventricular zone, known germinal centers in the adult mouse brain. It is not known whether β-catenin signaling occurs in
Autor:
Haneen Al-Azzawi, Jamie M. Goodson, Daniel G. Miller, Noah Simon, Minseung Choi, Stan Palasek, Diane P. Genereux, Kevin D. Sinclair, Shannon Q. Allain, Reinhard Stöger, Winslow C. Johnson, Chris Cavanaugh, Carol B. Ware, Charles D. Laird
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007060 (2017)
PLoS Genetics
PLoS Genetics
In storing and transmitting epigenetic information, organisms must balance the need to maintain information about past conditions with the capacity to respond to information in their current and future environments. Some of this information is encode