Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jamie L. Brady"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunoassays that quantitate cytokines and other surrogate markers of immunity from peripheral blood mononuclear cells (PBMCs), such as flow cytometry or Enzyme-Linked Immunosorbent Spot (ELIspot), allow highly sensitive measurements of immune effect
Externí odkaz:
https://doaj.org/article/09c97a78b98d4975ad7bc8257ae73d8a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Reliable extraction and sensitive detection of RNA from human peripheral blood mononuclear cells (PBMCs) is critical for a broad spectrum of immunology research and clinical diagnostics. RNA analysis platforms are dependent upon high-quality and high
Externí odkaz:
https://doaj.org/article/2e9ff1c6d5834441a797206f31b815ca
Autor:
Mark B. Nottle, Evelyn J. Salvaris, Nella Fisicaro, Stephen McIlfatrick, Ivan Vassiliev, Wayne J. Hawthorne, Philip J. O’Connell, Jamie L. Brady, Andrew M. Lew, Peter J. Cowan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Xenotransplantation from pigs has been advocated as a solution to the perennial shortage of donated human organs and tissues. CRISPR/Cas9 has facilitated the silencing of genes in donor pigs that contribute to xenograft rejection. However, t
Externí odkaz:
https://doaj.org/article/13fe765c6d834f9facf6f7bbc3879a6c
Autor:
Robyn M. Sutherland, Sarah L. Londrigan, Jamie L. Brady, Emma M. Carrington, Julia M. Marchingo, Susanne Heinzel, Philip D. Hodgkin, Kate L. Graham, Thomas W. Kay, Yifan Zhan, Andrew M. Lew
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Professional antigen presenting cells (APC) are the major activator of T cells that then hone to sites of inflammation. Using islet cell grafts, here the authors show that parenchymal cells can present antigen to activate CD8+T cells at inflammatory
Externí odkaz:
https://doaj.org/article/ddf258470896415aaf2e07fd3e6bba40
Autor:
Jamie L. Brady, Andrew M. Lew
Publikováno v:
BioTechniques, Vol 22, Iss 5, Pp 870-874 (1997)
Externí odkaz:
https://doaj.org/article/6e0c6e2fd65c4758ad0d5f236ee76e52
Publikováno v:
Cell Transplantation, Vol 10 (2001)
In a model of transplantation rejection, we have tested whether a graft manipulated to secrete immunomodulators could protect itself from immune destruction. An insulinoma cell line having the NOD genotype but also expressing the neoantigen, SV40 T a
Externí odkaz:
https://doaj.org/article/97a5ea51756d456d8f981c2772ceca24
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Immunoisolation is the separation of transplanted cells from cells of the immune system using a semipermeable membrane. Using one such immunoisolation capsule – -the TheraCyte® device – -we have assessed the survival of encapsulated xenogeneic t
Externí odkaz:
https://doaj.org/article/6248a8f9ac0d4f5695b6892ad006337e
Publikováno v:
SSRN Electronic Journal.
Immunoassays that quantitate cytokines and other surrogate markers of immunity from peripheral blood mononuclear cells (PBMCs), such as flow cytometry or Enzyme-Linked Immunosorbent Spot (ELIspot), allow highly sensitive measurements of immune effect
Autor:
Jamie L. Brady, Didier Doumtabe, Carla Proietti, Aissata Ongoiba, Karina P de Sousa, Peter D. Crompton, Kassoum Kayentao, Safiatou Doumbo, Boubacar Traore, Denise L. Doolan, Claire Loiseau
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 3, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology
Objectives Study of individuals with protection from Plasmodium falciparum (Pf) infection and clinical malaria, including individuals affected by the sickle‐cell trait (HbAS), offers the potential to identify cellular targets that could be translat
Autor:
Boubacar Traore, Carla Proietti, Katrina P. de Sousa, Jamie L. Brady, Peter D. Crompton, Denise L. Doolan, Claire Loiseau, Ogobara K. Doumbo
Publikováno v:
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 9, Iss 4, Pp n/a-n/a (2020)
Clinical & Translational Immunology, Vol 9, Iss 4, Pp n/a-n/a (2020)
Objectives The sickle‐cell trait phenotype is associated with protection from malaria. Multiple molecular mechanisms have been proposed to explain this protection, but the role of the host immune system has been poorly investigated. We hypothesised