Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jamie L, Maciaszek"'
Autor:
Jason R. Schwartz, Jing Ma, Jennifer Kamens, Tamara Westover, Michael P. Walsh, Samuel W. Brady, J. Robert Michael, Xiaolong Chen, Lindsey Montefiori, Guangchun Song, Gang Wu, Huiyun Wu, Cristyn Branstetter, Ryan Hiltenbrand, Michael F. Walsh, Kim E. Nichols, Jamie L. Maciaszek, Yanling Liu, Priyadarshini Kumar, John Easton, Scott Newman, Jeffrey E. Rubnitz, Charles G. Mullighan, Stanley Pounds, Jinghui Zhang, Tanja Gruber, Xiaotu Ma, Jeffery M. Klco
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Paediatric therapy-related myeloid neoplasms (tMN) have a dismal prognosis and have not been comprehensively profiled. Here the authors characterise the molecular landscape of 84 paediatric tMN patients, and find that, unlike adult tMNs, these do not
Externí odkaz:
https://doaj.org/article/fe707965968044aaa183257f76774e4d
Autor:
Xi Luo, Jamie L Maciaszek, Bryony A Thompson, Huei San Leong, Katherine Dixon, Sónia Sousa, Michael Anderson, Maegan E Roberts, Kristy Lee, Amanda B Spurdle, Arjen R Mensenkamp, Terra Brannan, Carolina Pardo, Liying Zhang, Tina Pesaran, Sainan Wei, Grace-Ann Fasaye, Chimene Kesserwan, Brian H Shirts, Jeremy L Davis, Carla Oliveira, Sharon E Plon, Kasmintan A Schrader, Rachid Karam
Publikováno v:
Journal of Medical Genetics, 60, 568-575
Journal of Medical Genetics, 60, 6, pp. 568-575
Journal of Medical Genetics, 60, 6, pp. 568-575
BackgroundGermline pathogenic variants inCDH1are associated with increased risk of diffuse gastric cancer and lobular breast cancer. Risk reduction strategies include consideration of prophylactic surgery, thereby making accurate interpretation of ge
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we present the spectrum of genomic alterations in 136 relapsed pediatric AMLs. We identified recurrent exon 13 tandem duplications (TD) in up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6c15e8269161afbfa878da7ad418de
https://doi.org/10.1158/2643-3230.c.6550658.v1
https://doi.org/10.1158/2643-3230.c.6550658.v1
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
Supplementary Data from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61856b4d04dd5ad8020d0a10bd090d6c
https://doi.org/10.1158/2643-3230.22544486
https://doi.org/10.1158/2643-3230.22544486
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
Supplementary Figure from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3154fb841a9f6b898d586b417fda9168
https://doi.org/10.1158/2643-3230.22544483.v1
https://doi.org/10.1158/2643-3230.22544483.v1
Autor:
Kim E. Nichols, Jinghui Zhang, James R. Downing, David W. Ellison, Ching-Hon Pui, Liza-Marie Johnson, Giles Robinson, Alberto S. Pappo, Stacy J. Hines-Dowell, Jessica M. Valdez, Leslie M. Taylor, Elsie L. Gerhardt, Roya Mostafavi, Regina Nuccio, Emily A. Quinn, Rose B. McGee, Charles G. Mullighan, Zhaohui Gu, Jian Wang, Alexander M. Gout, Jay Knight, Victor Pastor, Jamie L. Maciaszek, Manish Kubal, Delaram Rahbarinia, Mark R. Wilkinson, Aman Patel, Jared Becksfort, Eric Davis, Manjusha Pande, Ti-Cheng Chang, Xin Zhou, Samuel W. Brady, Yu Liu, Zhaojie Zhang, Yanling Liu, Antonina Silkov, Annastasia Ouma, Michael R. Clay, Lu Wang, Lynn W. Harrison, Jiali Gu, Jeffery M. Klco, Brent A. Orr, Armita Bahrami, Andrew Thrasher, Michael N. Edmonson, Scott G. Foy, Kayla V. Hamilton, Dale J. Hedges, Sheila Shurtleff, Michael Rusch, David A. Wheeler, Elizabeth M. Azzato, Chimene A. Kesserwan, Joy Nakitandwe, Scott Newman
Supplementary Figure S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1967bd812c67530d5a87837dd129084
https://doi.org/10.1158/2159-8290.22540643.v1
https://doi.org/10.1158/2159-8290.22540643.v1
Autor:
Kim E. Nichols, Jinghui Zhang, James R. Downing, David W. Ellison, Ching-Hon Pui, Liza-Marie Johnson, Giles Robinson, Alberto S. Pappo, Stacy J. Hines-Dowell, Jessica M. Valdez, Leslie M. Taylor, Elsie L. Gerhardt, Roya Mostafavi, Regina Nuccio, Emily A. Quinn, Rose B. McGee, Charles G. Mullighan, Zhaohui Gu, Jian Wang, Alexander M. Gout, Jay Knight, Victor Pastor, Jamie L. Maciaszek, Manish Kubal, Delaram Rahbarinia, Mark R. Wilkinson, Aman Patel, Jared Becksfort, Eric Davis, Manjusha Pande, Ti-Cheng Chang, Xin Zhou, Samuel W. Brady, Yu Liu, Zhaojie Zhang, Yanling Liu, Antonina Silkov, Annastasia Ouma, Michael R. Clay, Lu Wang, Lynn W. Harrison, Jiali Gu, Jeffery M. Klco, Brent A. Orr, Armita Bahrami, Andrew Thrasher, Michael N. Edmonson, Scott G. Foy, Kayla V. Hamilton, Dale J. Hedges, Sheila Shurtleff, Michael Rusch, David A. Wheeler, Elizabeth M. Azzato, Chimene A. Kesserwan, Joy Nakitandwe, Scott Newman
Genomic studies of pediatric cancer have primarily focused on specific tumor types or high-risk disease. Here, we used a three-platform sequencing approach, including whole-genome sequencing (WGS), whole-exome sequencing (WES), and RNA sequencing (RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0766fc82b48ecf1bf79e0f14636f6d6
https://doi.org/10.1158/2159-8290.c.6549437
https://doi.org/10.1158/2159-8290.c.6549437
Autor:
Marta Salek, Ninad Oak, Melissa Hines, Jamie L. Maciaszek, Ruth Tatevossian, Akshay Sharma, Kim E. Nichols, Patrick Campbell
Publikováno v:
Blood Advances. 6:2681-2684
Autor:
Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan M. Barajas, Melvin E. Thomas, Michael P. Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott G. Foy, Jamie L. Maciaszek, Andrew B. Kleist, Amanda R. Leonti, Bengsheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marcus B. Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason R. Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Publikováno v:
Blood Cancer Discov
Blood cancer discovery, vol 3, iss 3
Blood cancer discovery, vol 3, iss 3
The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we present the spectrum of genomic alterations in 136 relapsed pediatric AMLs. We identified recurrent exon 13 tandem duplications (TD) in up
Autor:
Lee Yi Yen, Melyssa Aronson, Carol J. Swallow, Cynthia Hawkins, Lara Reichman, Rebecca C. Luiten, Sumita Roy, Michal Zapotocky, Patrick Tomboc, Christian Kratz, Michael Osborn, Junne Kamihara, Ayse Bahar Ercan, Jamie L. Maciaszek, Vanessa Bianchi, Benjamin Oshrine, Hagit N. Baris, Ossama M. Maher, Mohsin Rashid, Sara Rhode, Sharon Gardner, Annika Bronsema, David S. Ziegler, An Van Damme, Monica Newmark, Mithra Ghalibafian, Heather Hampel, Jordan R. Hansford, Vahid Fallah Azad, Michael P. Link, Simon C. Ling, Marc Remke, Shayna Zelcer, Deborah T. Blumenthal, Isabelle Scheers, Rebecca Loret De Mola, Syed Ahmer Hamid, Vanan MagimairajanIssai, Kim E. Nichols, Saunders Hsu, Catherine Goudie, Naureen Mushtaq, Ira Winer, Abeer Al-Battashi, Garth Nicholas, Roula Farah, Kami Wolfe Schneider, Rejin Kebudi, Jan Rapp, Gregory Thomas, Helen Toledano, Alvaro Lassaletta, Anne Bendel, Jeffrey Knipstein, Musa Alharbi, Gadi Abebe-Campino, Rose B. McGee, Anirban Das, Uri Tabori, Donald Basel, Alyssa Reddy, Melissa Edwards, Scott Lindhorst, Craig Harlos, Bailey Gallinger, Elizabeth Cairney, Anita Villani, Valerie Larouche, Rachel Pearlman, Maude Blundell, Gary Mason, David Sumerauer, Magnus Sabel, Aghiad Chamdin, Leslie Taylor, David Malkin, William D. Foulkes, Maura Massimino, Catherine Gilpin, Eric Bouffet, Miriam Bornhorst, Carol Durno, Enrico Opocher, Nobuko Hijiya, Zehavit Frenkel, David Samuel, Michal Lurye, Stefanie Zimmermann, Shani Caspi, Stefano Chiaravalli, David Gass, Eshetu G. Atenafu, Shlomi Constantini, Shay Ben-Shachar, Michal Yalon, Rina Dvir, Daniel Pettee, Bruce Crooks, Santanu Sen, Carl Koschmann, Raymond Bedgood, Theodore Nicolaides, Duncan Stearns, Yael Goldberg, Melissa Galati, Gabriel Robbins
Publikováno v:
Paediatrics Publications
Journal of Clinical Oncology, Vol. 39, no.25, p. 2779-2790 (2021)
Journal of Clinical Oncology, Vol. 39, no.25, p. 2779-2790 (2021)
PURPOSE Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer predisposition syndrome characterized by early-onset synchronous and metachronous multiorgan tumors. We designed a surveillance protocol for early tumor detection i