Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jamie L, Everman"'
Autor:
Jamie L. Everman, Satria P. Sajuthi, Maude A. Liegeois, Nathan D. Jackson, Erik H. Collet, Michael C. Peters, Maurizio Chioccioli, Camille M. Moore, Bhavika B. Patel, Nathan Dyjack, Roger Powell, Cydney Rios, Michael T. Montgomery, Celeste Eng, Jennifer R. Elhawary, Angel C. Y. Mak, Donglei Hu, Scott Huntsman, Sandra Salazar, Luigi Feriani, Ana Fairbanks-Mahnke, Gianna L. Zinnen, Cole R. Michel, Joe Gomez, Xing Zhang, Vivian Medina, Hong Wei Chu, Pietro Cicuta, Erin D. Gordon, Pamela Zeitlin, Victor E. Ortega, Nichole Reisdorph, Eleanor M. Dunican, Monica Tang, Brett M. Elicker, Travis S. Henry, Eugene R. Bleecker, Mario Castro, Serpil C. Erzurum, Elliot Israel, Bruce D. Levy, David T. Mauger, Deborah A. Meyers, Kaharu Sumino, David S. Gierada, Annette T. Hastie, Wendy C. Moore, Loren C. Denlinger, Nizar N. Jarjour, Mark L. Schiebler, Sally E. Wenzel, Prescott G. Woodruff, Jose Rodriguez-Santana, Chad G. Pearson, Esteban G. Burchard, John V. Fahy, Max A. Seibold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract By incompletely understood mechanisms, type 2 (T2) inflammation present in the airways of severe asthmatics drives the formation of pathologic mucus which leads to airway mucus plugging. Here we investigate the molecular role and clinical si
Externí odkaz:
https://doaj.org/article/e5fbd453726447a6a3e42371a05beeb5
Autor:
Nathan D. Jackson, Nathan Dyjack, Elena Goleva, Lianghua Bin, Michael T. Montgomery, Cydney Rios, Jamie L. Everman, Patricia Taylor, Caroline Bronchick, Brittany N. Richers, Donald Y.M. Leung, Max A. Seibold
Publikováno v:
JID Innovations, Vol 4, Iss 4, Pp 100279- (2024)
A subgroup of patients with atopic dermatitis (AD) suffers from recurrent, disseminated herpes simplex virus skin infection, termed eczema herpeticum. To determine the transcriptional mechanisms of the skin and immune system pathobiology that underli
Externí odkaz:
https://doaj.org/article/5ac4c762010240c089e6706b050cde60
Autor:
Javier Perez-Garcia, Maria Pino-Yanes, Elizabeth G. Plender, Jamie L. Everman, Celeste Eng, Nathan D. Jackson, Camille M. Moore, Kenneth B. Beckman, Vivian Medina, Sunita Sharma, Daniel Efrain Winnica, Fernando Holguin, José Rodríguez-Santana, Jesús Villar, Elad Ziv, Max A. Seibold, Esteban G. Burchard
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Albuterol is the first-line asthma medication used in diverse populations. Although DNA methylation (DNAm) is an epigenetic mechanism involved in asthma and bronchodilator drug response (BDR), no study has assessed whether albuter
Externí odkaz:
https://doaj.org/article/dd94221e29c147b18ed997f3b41be0f7
Autor:
Satria P. Sajuthi, Jamie L. Everman, Nathan D. Jackson, Benjamin Saef, Cydney L. Rios, Camille M. Moore, Angel C. Y. Mak, Celeste Eng, Ana Fairbanks–Mahnke, Sandra Salazar, Jennifer Elhawary, Scott Huntsman, Vivian Medina, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Noah A. Zaitlen, Sam Oh, NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium, José Rodríguez–Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Externí odkaz:
https://doaj.org/article/2becd8c53e824b738a9f10d4fbec7c85
Autor:
Satria P. Sajuthi, Jamie L. Everman, Nathan D. Jackson, Benjamin Saef, Cydney L. Rios, Camille M. Moore, Angel C. Y. Mak, Celeste Eng, Ana Fairbanks-Mahnke, Sandra Salazar, Jennifer Elhawary, Scott Huntsman, Vivian Medina, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Noah A. Zaitlen, Sam Oh, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, José Rodríguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Understanding regulation of genes associated to disease can reveal insights into disease mechanisms. Here, the authors perform an airway epithelial transcriptome-wide association analysis to elucidate genetic determinants of airway dysfunction in ast
Externí odkaz:
https://doaj.org/article/f0bfdc317fbf49d288c90aff61c49c7f
Autor:
Satria P. Sajuthi, Peter DeFord, Yingchun Li, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel C. Y. Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
ACE2 and TMPRSS2 have received recent attention as entry factors for SARS-CoV-2. Here the authors analyze nasal airway transcriptome data from 695 children determining ACE2 and TMPRSS2 expression is induced by viral and type2 inflammation, respective
Externí odkaz:
https://doaj.org/article/5998991851af4757adcf82673111f6e4
Autor:
Katherine C. Goldfarbmuren, Nathan D. Jackson, Satria P. Sajuthi, Nathan Dyjack, Katie S. Li, Cydney L. Rios, Elizabeth G. Plender, Michael T. Montgomery, Jamie L. Everman, Preston E. Bratcher, Eszter K. Vladar, Max A. Seibold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tu
Externí odkaz:
https://doaj.org/article/9bcec16a7aeb4036b62487f931077a83
Autor:
Agata Wesolowska-Andersen, Jamie L. Everman, Rebecca Davidson, Cydney Rios, Rachelle Herrin, Celeste Eng, William J. Janssen, Andrew H. Liu, Sam S. Oh, Rajesh Kumar, Tasha E. Fingerlin, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Respiratory illness caused by viral infection is associated with the development and exacerbation of childhood asthma. Little is known about the effects of respiratory viral infections in the absence of illness. Using quantitative
Externí odkaz:
https://doaj.org/article/f49dee92afad46829bbfda924b782b65
Autor:
Max A, Seibold, Camille M, Moore, Jamie L, Everman, Blake J M, Williams, James D, Nolin, Ana, Fairbanks-Mahnke, Elizabeth G, Plender, Bhavika B, Patel, Samuel J, Arbes, Leonard B, Bacharier, Casper G, Bendixsen, Agustin, Calatroni, Carlos A, Camargo, William D, Dupont, Glenn T, Furuta, Tebeb, Gebretsadik, Rebecca S, Gruchalla, Ruchi S, Gupta, Gurjit K, Khurana Hershey, Liza Bronner, Murrison, Daniel J, Jackson, Christine C, Johnson, Meyer, Kattan, Andrew H, Liu, Stephanie J, Lussier, George T, O'Connor, Katherine, Rivera-Spoljaric, Wanda, Phipatanakul, Marc E, Rothenberg, Christine M, Seroogy, Stephen J, Teach, Edward M, Zoratti, Alkis, Togias, Patricia C, Fulkerson, Tina V, Hartert
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:302-311
Whether children and people with asthma and allergic diseases are at increased risk for severe acute respiratory syndrome virus 2 (SARS-CoV-2) infection is unknown.Our aims were to determine the incidence of SARS-CoV-2 infection in households with ch
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1571 (2020)
The high prevalence of Johne’s disease has driven a continuous effort to more readily understand the pathogenesis of the etiological causative bacterium, Mycobacterium avium subsp. paratuberculosis (MAP), and to develop effective preventative measu
Externí odkaz:
https://doaj.org/article/d2e70a31f4084081bae218b8d217462c