Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Jamie K. Hobbs"'
Autor:
Matthew Cook, Ben Stevenson, Laura A. Jacobs, Daniel Leocadio Victoria, Bulmaro Cisneros, Jamie K. Hobbs, Colin L. Stewart, Steve J. Winder
Publikováno v:
Cells, Vol 13, Iss 5, p 431 (2024)
Dystroglycan is a ubiquitously expressed heterodimeric cell-surface laminin receptor with roles in cell adhesion, signalling, and membrane stabilisation. More recently, the transmembrane β-subunit of dystroglycan has been shown to localise to both t
Externí odkaz:
https://doaj.org/article/04576a76b1c445ed86dab1d4022de61c
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Most bacteria are surrounded by their cell wall, containing a highly cross-linked protective envelope of peptidoglycan. To grow, bacteria must continuously remodel their wall, inserting new material and breaking old bonds. Bond cleavage is p
Externí odkaz:
https://doaj.org/article/7747bee986eb4da8b724635fc1c367ee
Autor:
Joshua A. F. Sutton, Mark Cooke, Mariana Tinajero-Trejo, Katarzyna Wacnik, Bartłomiej Salamaga, Callum Portman-Ross, Victoria A. Lund, Jamie K. Hobbs, Simon J. Foster
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The spheroid bacterium Staphylococcus aureus is often used as a model of morphogenesis due to its apparently simple cell cycle. S. aureus has many cell division proteins that are conserved across bacteria alluding to common functions. However, despit
Externí odkaz:
https://doaj.org/article/be7c4e711403437dafa287a64898ba25
Autor:
Mariana Tinajero-Trejo, Oliver Carnell, Azhar F. Kabli, Laia Pasquina-Lemonche, Lucia Lafage, Aidong Han, Jamie K. Hobbs, Simon J. Foster
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The conserved division protein DivIC in the human pathogen Staphylococcus aureus controls cell division through the recruitment of major cell wall synthesis enzymes to the division site.
Externí odkaz:
https://doaj.org/article/45c18fe41033400794e1a8249ae66501
Autor:
Katarzyna Wacnik, Vincenzo A. Rao, Xinyue Chen, Lucia Lafage, Manuel Pazos, Simon Booth, Waldemar Vollmer, Jamie K. Hobbs, Richard J. Lewis, Simon J. Foster
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Bacterial cell division is a complex process requiring the coordination of multiple components to allow the appropriate spatial and temporal control of septum formation and cell scission. Peptidoglycan (PG) is the major structural component
Externí odkaz:
https://doaj.org/article/7ea851c91c764329a9c947d3d0339c7f
Autor:
Thamarai K. Janganan, Nic Mullin, Ainhoa Dafis-Sagarmendi, Jason Brunt, Svetomir B. Tzokov, Sandra Stringer, Anne Moir, Roy R. Chaudhuri, Robert P. Fagan, Jamie K. Hobbs, Per A. Bullough
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Spores, the infectious agents of many Firmicutes, are remarkably resilient cell forms. Even distant relatives can have similar spore architectures although some display unique features; they all incorporate protective proteinaceous envelopes
Externí odkaz:
https://doaj.org/article/41d109989bd9469a8966c01fd5b8668e
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT The bacterial cell envelope is essential for viability, the environmental gatekeeper and first line of defense against external stresses. For most bacteria, the envelope biosynthesis is also the site of action of some of the most important g
Externí odkaz:
https://doaj.org/article/31a3d179ed814a4cbac5e124eef6af12
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
The molecular architecture of peptidoglycan in the bacterial cell wall remains unclear. Here, Turner et al. use atomic force microscopy to image individual glycan strands in peptidoglycan at an unprecedented detail, revealing novel features of its mo
Externí odkaz:
https://doaj.org/article/ae44febeae124aef9f3034a47e9d0d02
Autor:
Russell Hughes, Xinyue Chen, Natasha Cowley, Penelope D. Ottewell, Rhoda J. Hawkins, Keith D. Hunter, Jamie K. Hobbs, Nicola J. Brown, Ingunn Holen
Publikováno v:
Cancers, Vol 13, Iss 6, p 1366 (2021)
Metastatic breast cancer in bone is incurable and there is an urgent need to develop new therapeutic approaches to improve survival. Key to this is understanding the mechanisms governing cancer cell survival and growth in bone, which involves interpl
Externí odkaz:
https://doaj.org/article/8c31729609b5434984e8fcbac523fc76
Autor:
Richard Wheeler, Robert D. Turner, Richard G. Bailey, Bartłomiej Salamaga, Stéphane Mesnage, Sharifah A. S. Mohamad, Emma J. Hayhurst, Malcolm Horsburgh, Jamie K. Hobbs, Simon J. Foster
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target.
Externí odkaz:
https://doaj.org/article/e66b353d918c46598f6da00f90e1f90d