Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jamie Josephine Avila McLeod"'
Autor:
Kaitlyn Jackson, Rebecca K. Martin, E. Motunrayo Kolawole, Patrick A Paez, Jamie Josephine Avila McLeod, John J. Ryan, Matthew P. Zellner, Bianca Baker, Tamara T. Haque, Kasalina N. Kiwanuka, Anuya Paranjape, Jordan M. Dailey, Sydney A. Kee
Publikováno v:
Cell Immunol
Mast cells are found primarily at interfaces with the external environment, where they provide protection from pathogens but also elicit allergic inflammation. Mast cell activation by antigen-induced aggregation of IgE bound to the high affinity rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14f32184c1ca7aff5199053ec82e0fe
https://doi.org/10.1016/j.cellimm.2021.104344
https://doi.org/10.1016/j.cellimm.2021.104344
Autor:
John J. Ryan, E. Motunrayo Kolawole, Heather L. Caslin, David B. Straus, Patrick A Paez, Rebecca K. Martin, Brian O. Barnstein, Siddarth Ajith, Jamie Josephine Avila McLeod, Marcela T. Taruselli, Lawrence B. Schwartz, David A. Gewirtz, Quang T. Le, Yoshihiro Fukuoka, Kasalina N. Kiwanuka, Tamara T. Haque, Jordan M. Dailey, Sydney A. Kee
Publikováno v:
J Pharmacol Exp Ther
Statin drugs are widely employed in the clinic to reduce serum cholesterol. Because of their hydroxymethylglutaryl coenzyme A reductase antagonism, statins also reduce isoprenyl lipids necessary for the membrane anchorage and signaling of small G-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e1893c555a9fbd145216ab640f613
https://pubmed.ncbi.nlm.nih.gov/32434944
https://pubmed.ncbi.nlm.nih.gov/32434944
Autor:
Marcela T. Taruselli, John J. Ryan, Jamie Josephine Avila McLeod, Andrew J. Spence, Amina Abdul Qayum, Victor S. Ndaw, Bianca Baker, Heather L. Caslin, Alena P. Chumanevich, Brian O. Barnstein, Elizabeth Motunrayo Kolawole, Daniel Abebayehu, Anuya Paranjape, Carole A. Oskeritzian, Scott A. Sell
Publikováno v:
The Journal of Immunology. 197:2909-2917
Lactic acid (LA) is present in tumors, asthma, and wound healing, environments with elevated IL-33 and mast cell infiltration. Although IL-33 is a potent mast cell activator, how LA affects IL-33–mediated mast cell function is unknown. To investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17b2eb884379d36d090d6c06dfdf2c0
https://doi.org/10.4049/jimmunol.1600651
https://doi.org/10.4049/jimmunol.1600651
Autor:
Heather L. Caslin, Amina Abdul Qayum, Andrew J. Spence, Jamie Josephine Avila McLeod, Elizabeth Motunrayo Kolawole, Howard L. Elford, John J. Ryan, Marcela T. Taruselli, Kasalina N. Kiwanuka, Tamara T. Haque, Anuya Paranjape
Publikováno v:
Cellular immunology. 322
Mast cell activation via the high-affinity IgE receptor (FcεRI) elicits production of inflammatory mediators central to allergic disease. As a synthetic antioxidant and a potent ribonucleotide reductase (RNR) inhibitor, Didox (3,4-dihyroxybenzohydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00de135f858689537c06335caa8a20ef
https://pubmed.ncbi.nlm.nih.gov/28964543
https://pubmed.ncbi.nlm.nih.gov/28964543
Autor:
Anuya Paranjape, Marcela T. Taruselli, Amina Abdul Qayum, Andrew J. Spence, John J. Ryan, Heather L. Caslin, Jamie Josephine Avila McLeod, Elizabeth Motunrayo Kolawole, Howard L. Elford
Publikováno v:
Cellular immunology. 319
While IgE is considered the primary mediator of mast cell activation, IL-33 contributes substantially in asthma, allergic rhinitis, and atopic dermatitis. To develop effective treatments for allergic disease, it is important to understand the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7911a896c43185dc3e4c394275891ada
https://pubmed.ncbi.nlm.nih.gov/28750923
https://pubmed.ncbi.nlm.nih.gov/28750923
Autor:
Kevin O. Rivera, Daniel H. Conrad, Nicholas Pullen, Jamie Josephine Avila McLeod, Brian O. Barnstein, John J. Ryan, Elizabeth Motunrayo Kolawole, Josephine Fernando, Travis Faber, Marcela T. Taruselli, Kathryn L. Williams
Publikováno v:
Cellular Immunology. 290:80-88
A Disintegrin And Metalloproteinase (ADAM)-10 plays critical roles in neuronal migration and distribution. Recently, ADAM10 deletion was shown to disrupt myelopoiesis. We found that inducible deletion of ADAM10 using Mx1-driven Cre recombinase for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1605913c271f8808a8ba627eb25d2b35
https://doi.org/10.1016/j.cellimm.2014.05.005
https://doi.org/10.1016/j.cellimm.2014.05.005
Autor:
Robert M. Tombes, Sarah C. Rothschild, Jamie L. Lahvic, Jamie Josephine Avila McLeod, Ludmila Francescatto, Shawn M. Burgess
Publikováno v:
Developmental Biology. 381:179-188
Zebrafish inner ear development is characterized by the crystallization of otoliths onto immotile kinocilia that protrude from sensory “hair” cells. The stereotypical formation of these sensory structures is dependent on the expression of key pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22eaa35eb92016f5076fe61af0016547
https://doi.org/10.1016/j.ydbio.2013.05.028
https://doi.org/10.1016/j.ydbio.2013.05.028
Autor:
Amina Abdul Qayum, Andrew J. Spence, Jamie Josephine Avila McLeod, Carole A. Oskeritzian, Brian O. Barnstein, Daniel Abebayehu, Gurjas S. Bajaj, Bianca Baker, Alena P. Chumanevich, Anuya Paranjape, Marcela T. Taruselli, Oksana Chernushevich, John J. Ryan
Mast cells are critical effectors of allergic disease and can be activated by IL-33, a proinflammatory member of the IL-1 cytokine family. IL-33 worsens the pathology of mast cell–mediated diseases, but therapies to antagonize IL-33 are still forth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a689213148feb9994e9ede4bc91b86
https://europepmc.org/articles/PMC5109997/
https://europepmc.org/articles/PMC5109997/
Autor:
Anuya Paranjape, Andrew J. Spence, Marcela T. Taruselli, Jamie Josephine Avila McLeod, Heather L. Caslin, Bianca Baker, Alena P. Chumanevich, Daniel Abebayehu, John J. Ryan, Amina Abdul Qayum, Elizabeth Motunrayo Kolawole, Tamara T. Haque, Carole A. Oskeritzian
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(11)
IL-10 is an important regulatory cytokine that modulates a wide range of immune cells. Whereas it is best known for its ability to suppress immune responses, IL-10 has been found to be pathogenic in several human and animal studies of immune-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4451f72d718ceee28cfd6e23a4412c6
https://pubmed.ncbi.nlm.nih.gov/27183599
https://pubmed.ncbi.nlm.nih.gov/27183599
Autor:
Andrew J. Spence, Charles E. Chalfant, Marcela T. Taruselli, Amina Abdul Qayum, Jamie Sturgill, Victor S. Ndaw, Tamara T. Haque, John J. Ryan, Qasim A. Kazmi, Elizabeth Motunrayo Kolawole, David B. Straus, Travis Faber, Jamie Josephine Avila McLeod, Anuya Paranjape, Daniel Abebayehu, Carole A. Oskeritzian, Brian O. Barnstein, Dayanjan S. Wijesinghe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(4)
Mast cell (MC)– and basophil-associated inflammatory diseases are a considerable burden to society. A significant portion of patients have symptoms despite standard-of-care therapy. Statins, used to lower serum cholesterol, have immune-modulating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6830e6ae9a7fe4ba1b4927b8a27792b1
https://pubmed.ncbi.nlm.nih.gov/26773154
https://pubmed.ncbi.nlm.nih.gov/26773154