Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jamie J. Kwan"'
Autor:
Gregory M. Kent, Michael H. Atkins, Bryan Lung, Adele Nikitina, Ian M. Fernandes, Jamie J. Kwan, Tallulah S. Andrews, Sonya A. MacParland, Gordon M. Keller, Blair K. Gage
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114629- (2024)
Summary: In mice, the first liver-resident macrophages, known as Kupffer cells (KCs), are thought to derive from yolk sac (YS) hematopoietic progenitors that are specified prior to the emergence of the hematopoietic stem cell (HSC). To investigate hu
Externí odkaz:
https://doaj.org/article/02df4a49d2314ca5a9d8b39bd4826aa0
Autor:
Barbara Mair, Jelena Tomic, Sanna N. Masud, Peter Tonge, Alexander Weiss, Matej Usaj, Amy Hin Yan Tong, Jamie J. Kwan, Kevin R. Brown, Emily Titus, Michael Atkins, Katherine S.K. Chan, Lise Munsie, Andrea Habsid, Hong Han, Marion Kennedy, Brenda Cohen, Gordon Keller, Jason Moffat
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 599-615.e12 (2019)
Summary: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms, a critical first step involves systemati
Externí odkaz:
https://doaj.org/article/b48e7be0191349729bde89c8056e0021
Autor:
Sladjana Slavkovic, Michael Piazza, Philip E. Johnson, Logan W. Donaldson, Thorsten Dieckmann, Dingyan Wang, Jamie J. Kwan, Xiao-Yan Wen
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology
Communications Biology
Hematopoietic adaptor containing SH3 and SAM domains-1 (HACS1) is a signaling protein with two juxtaposed protein–protein interaction domains and an intrinsically unstructured region that spans half the sequence. Here, we describe the interaction b
Autor:
Michael Atkins, Marion Kennedy, Kevin R. Brown, Sanna Masud, Katherine S. K. Chan, Lise Munsie, Matej Usaj, Gordon Keller, Brenda Cohen, Amy Hin Yan Tong, Barbara Mair, Alexander Weiss, Emily Titus, Andrea Habsid, Jamie J. Kwan, Jason Moffat, Hong Han, Peter Tonge, Jelena Tomic
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 599-615.e12 (2019)
Summary: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms, a critical first step involves systemati
Autor:
Ekaterina Smirnova, Vivian Saridakis, Georg Zoidl, Xin Gao, Ryan Siu, Logan W. Donaldson, Jamie J. Kwan, Borries Demeler
Publikováno v:
Cell Communication and Signaling : CCS
Background CASKIN2 is a homolog of CASKIN1, a scaffolding protein that participates in a signaling network with CASK (calcium/calmodulin-dependent serine kinase). Despite a high level of homology between CASKIN2 and CASKIN1, CASKIN2 cannot bind CASK
Publikováno v:
Journal of Molecular Biology. 392:1168-1177
The neuronal scaffolding protein AIDA-1 is believed to act as a convener of signals arising at postsynaptic densities. Among the readily identifiable domains in AIDA-1, two closely juxtaposed sterile alpha motif (SAM) domains and a phosphotyrosine bi
Autor:
Logan W. Donaldson, Irene Yang, Alan R. Davidson, Jamie J. Kwan, John L.R. Rubenstein, Lizbeth Edmonds, Mary Caracoglia, Aida Avanessy, Amanda Liu, Karen L. Maxwell
Publikováno v:
Journal of Molecular Biology. 365:175-186
During the late stages of lambda bacteriophage assembly, the protein gpU terminates tail polymerization and participates at the interface between the mature capsid and tail components. When it engages the lambda tail, gpU undergoes a monomer-hexamer
Autor:
Shokofeh Shahangian, Jamie J. Kwan, Naveen Khan, Sarah N. Ramsook, Joyce Ni, Ana Vakiloroayaei, Logan W. Donaldson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161432 (2016)
PLoS ONE, Vol 11, Iss 8, p e0161432 (2016)
Group E members of the SOX transcription factor family include SOX8, SOX9, and SOX10. Preceding the high mobility group (HMG) domain in each of these proteins is a thirty-eight amino acid region that supports the formation of dimers on promoters cont
Autor:
Logan W. Donaldson, Jamie J. Kwan, Ekaterina Smirnova, Shahin Khazai, Karen L. Maxwell, Ferenc Evanics
Publikováno v:
Biochemistry. 52:3612-3614
A cluster of genes in the exoxis region of bacteriophage λ are capable of inhibiting the initiation of DNA synthesis in Escherichia coli. The most indispensible gene in this region is ea8.5. Here, we report the nuclear magnetic resonance structures
Autor:
Ekaterina Smirnova, Jamie J. Kwan, Mehdi Mobli, Riya Shanbhag, Arwa Kurabi, Logan W. Donaldson
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65605 (2013)
PLoS ONE
PLoS ONE
AIDA1 links persistent chemical signaling events occurring at the neuronal synapse with global changes in gene expression. Consistent with its role as a scaffolding protein, AIDA1 is composed of several protein-protein interaction domains. Here we re