Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jamie H. Rosenblum Lichtenstein"'
Autor:
Jamie H Rosenblum Lichtenstein, Yi-Hsiang Hsu, Igor M Gavin, Thomas C Donaghey, Ramon M Molina, Khristy J Thompson, Chih-Lin Chi, Bruce S Gillis, Joseph D Brain
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126926 (2015)
Molds can cause respiratory symptoms and asthma. We sought to use isolated peripheral blood mononuclear cells (PBMCs) to understand changes in cytokine and chemokine levels in response to mold and mycotoxin exposures and to link these levels with res
Externí odkaz:
https://doaj.org/article/3182905021f5486abf3615337c1d48de
Autor:
Joseph D. Brain, Yi-Hsiang Hsu, Jamie H. Rosenblum Lichtenstein, Joel A. Mathews, Bruce S. Gillis, Andre Bordini, Thomas C. Donaghey, Jin-Ah Park, John J. Godleski, David I. Kasahara, Ramon M. Molina
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:521-531
After a single or multiple intratracheal instillations of Stachybotrys chartarum (S. chartarum or black mold) spores in BALB/c mice, we characterized cytokine production, metabolites, and inflammatory patterns by analyzing mouse bronchoalveolar lavag
Autor:
Christa Watson, Joseph D. Brain, Thomas C. Donaghey, Sylvia Rodrigues, Ramon M. Molina, Jamie H. Rosenblum Lichtenstein, Sumati Ram-Mohan, Ramaswamy Krishnan, Priscila de Moura Queiroz, Flavia Damiani
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 150(1)
To assess chemical toxicity, current high throughput screening (HTS) assays rely primarily on in vitro measurements using cultured cells. Responses frequently differ from in vivo results due to the lack of physical and humoral interactions provided b
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 35:415-423
When the fungus Stachybotrys chartarum is inhaled, its mycotoxins may cause lung injury and inflammation. The severity of human responses to S. chartarum in both occupational and home settings varies widely. To explore these differences, we intratrac
Autor:
Joseph D. Brain, Ramon M. Molina, Bruce S. Gillis, Thomas C. Donaghey, Khristy J. Thompson, Igor M. Gavin, Chih-Lin Chi, Jamie H. Rosenblum Lichtenstein, Yi-Hsiang Hsu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0126926 (2015)
PLoS ONE, Vol 10, Iss 5, p e0126926 (2015)
Background Molds can cause respiratory symptoms and asthma. We sought to use isolated peripheral blood mononuclear cells (PBMCs) to understand changes in cytokine and chemokine levels in response to mold and mycotoxin exposures and to link these leve
Autor:
Joseph D. Brain, Ramon M. Molina, Brent A. Coull, Thomas C. Donaghey, James J. Pestka, Jamie H. Rosenblum Lichtenstein, Chidozie J. Amuzie
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 116(1)
We investigated differences in the pulmonary and systemic clearance of Stachybotrys chartarum spores in two strains of mice, BALB/c and C57BL/6J. To evaluate clearance, mice were intratracheally instilled with a suspension of radiolabeled S. chartaru
Publikováno v:
The Journal of Immunology. 178:S98-S98
The fungus Stachybotrys chartarum (S. chartarum) releases mycotoxins that can cause lung injury, inflammation, hemorrhage and cytotoxicity. We have shown that when BALB/c mice receive instilled spores, they have greater lung inflammation, hemorrhage,