Discriminative ability of quality of life measures in multiple sclerosis

Autor: Kirsten M. Fiest, Jamie Greenfield, Luanne M. Metz, Scott B. Patten, Nathalie Jetté, Ruth Ann Marrie

Publikováno v: Health and Quality of Life Outcomes, Vol 15, Iss 1, Pp 1-9 (2017)

Abstract Background Though many people with multiple sclerosis (MS) have comorbidities, the use of generic and disease-specific health related quality of life (HRQOL) scales to discriminate the effects of comorbidity has not been established. The uti

Externí odkaz: https://doaj.org/article/4989d7daeabb492c9385d0ed5db28732

Minocycline treatment in clinically isolated syndrome and serum NfL, GFAP, and metalloproteinase levels

Autor: Carlos Camara-Lemarroy, Luanne Metz, Jens Kuhle, David Leppert, Eline Willemse, David KB Li, Anthony Traboulsee, Jamie Greenfield, Graziela Cerchiaro, Claudia Silva, V Wee Yong

Publikováno v: Camara-Lemarroy, C, Metz, L, Kuhle, J, Leppert, D, Willemse, E, Li, D K B, Traboulsee, A, Greenfield, J, Cerchiaro, G, Silva, C & Yong, V W 2022, ' Minocycline treatment in clinically isolated syndrome and serum NfL, GFAP, and metalloproteinase levels ', Multiple Sclerosis Journal, vol. 28, no. 13, pp. 2081-2089 . https://doi.org/10.1177/13524585221109761
Multiple Sclerosis Journal, 28(13), 2081-2089. SAGE Publications Ltd

Background: In the trial of Minocycline in Clinically Isolated Syndrome (MinoCIS), minocycline significantly reduced the risk of conversion to clinically definite multiple sclerosis (CDMS). Neurofilament light chain (NfL) and glial fibrillary acidic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f238d4df8c5f2f4d67201f642939ae9
https://research.vumc.nl/en/publications/3fc0f334-f7ae-4152-8b84-d77f850d60df

Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis

Autor: James Lee, Guojun Zhao, Irene M. Vavasour, Anthony Trablousee, G. R. Wayne Moore, Luanne M. Metz, David K.B. Li, Roger Tam, Cornelia Laule, Jamie Greenfield, R Davis Holmes

Publikováno v: Journal of Neuroimaging. 31:981-994

Background and purpose While diffusely abnormal white matter (DAWM) is a nonlesional MRI abnormality identified in ∼25% of patients with multiple sclerosis (MS), it has yet to be investigated in patients at an earlier disease stage, namely clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698829f1c2ddda95df8467b829b16f6c
https://doi.org/10.1111/jon.12900

Time-Varying Proteinuria and the Risk of Cardiovascular Disease and Graft Failure in Kidney Transplant Recipients

Autor: Monika Ashwin, Tanya Kuper, Tanya Narang, Yanhong Li, Syed Ibrahim, S. Joseph Kim, Olusegun Famure, Jamie Greenfield

Publikováno v: Progress in transplantation (Aliso Viejo, Calif.). 31(4)

Introduction: Proteinuria is recognized as an independent risk factor for cardiovascular disease in kidney transplant recipients, but previous studies have not considered the impact of changes in urine protein over time. Research Question and Design:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fa5e3e073291c0fe1e29ccacb88a7d
https://pubmed.ncbi.nlm.nih.gov/34839728

Gadolinium enhancement on cranial MRI in multiple sclerosis is age dependent

Autor: Wei-Qiao Liu, Jamie Greenfield, Luanne M. Metz, Jop P. Mostert, Marcus W. Koch

Publikováno v: Journal of neurology. 267(9)

Epidemiological, pathological and radiological studies suggest that inflammatory demyelination in MS is an age-dependent process, and that the formation of focal inflammatory demyelinating lesions decreases with age. Gadolinium-enhancing lesions are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c9ff082acfbe0f3b6111fe6b872fbc
https://pubmed.ncbi.nlm.nih.gov/32388832