Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jamie G Bates"'
Autor:
Jamie G Bates, Julia Salzman, Damon May, Patty B Garcia, Gregory J Hogan, Martin McIntosh, Mark S Schlissel, Pat O Brown
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37108 (2012)
To what extent might the regulation of translation contribute to differentiation programs, or to the molecular pathogenesis of cancer? Pre-B cells transformed with the viral oncogene v-Abl are suspended in an immortalized, cycling state that mimics l
Externí odkaz:
https://doaj.org/article/a5490331ec3f4eff8fe0964b67a33397
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43805 (2012)
Regulated expression of miRNAs influences development in a wide variety of contexts. We report here that miR290-5p (100049710) and miR292-5p (100049711) are induced at the pre-B stage of murine B cell development and that they influence assembly of t
Externí odkaz:
https://doaj.org/article/40defe79faf44058ad0b19500811096e
Autor:
James L. Trevaskis, Diego A. Miranda, Michael Feigh, Jenny Norlin, Sanne Skovgård Veidal, Markus Latta, Jamie G. Bates, Nora E. Zois
Publikováno v:
Diabetes. 69
Semaglutide (SEMA), FXR agonists and ACC inhibitors are under active clinical investigation for the treatment of NASH. Here, we explored whether the effects of SEMA (0.12 mg/kg, s.c., q.d.) on NASH endpoints could be enhanced by addition of an FXR ag
Autor:
Michael Feigh, Jenny Norlin, James L. Trevaskis, Nora E. Zois, Diego A. Miranda, Markus Latta, Jamie G. Bates, Sanne Skovgård Veidal
Publikováno v:
Diabetes. 69
Combination approaches for the treatment of NASH are being actively pursued. We examined the effects of administration of a dual GLP-1 and glucagon receptor agonist (GLP-1:GCG, 0.015 mg/kg, s.c., q.d.) alone and combined with an FXR agonist (cilofexo
Autor:
Claudia Bossen, Chunguang Guo, Frederick W. Alt, Andrew Franklin, Darienne Myers, Michael P. Gallagher, Suvi Jain, Cosmas Giallourakis, Orion Despo, Erica Hansen, Jamie G. Bates, Christian Vettermann, Meinrad Busslinger, Anja Ebert, Harin Patel, Cornelis Murre, Mark S. Schlissel, Nicholas Richards, Hwei-Ling Cheng, Hye Suk Yoon
Publikováno v:
Nature
Immunoglobulin heavy chain (IgH) variable region exons are assembled from V(H), D and J(H) gene segments in developing B lymphocytes. Within the 2.7-megabase mouse Igh locus, V(D)J recombination is regulated to ensure specific and diverse antibody re
Publikováno v:
The Journal of Experimental Medicine
Complete IgHC gene rearrangement occurs only in B cells in a stage-specific and ordered manner. We used gene targeting to reposition a distal VH gene segment to a region just 5′ of the DH gene cluster and found its activation to be highly dependent
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43805 (2012)
PLoS ONE
PLoS ONE
Regulated expression of miRNAs influences development in a wide variety of contexts. We report here that miR290-5p (100049710) and miR292-5p (100049711) are induced at the pre-B stage of murine B cell development and that they influence assembly of t
Autor:
Gregory J. Hogan, Patrick O. Brown, Damon May, Mark S. Schlissel, Jamie G. Bates, Patty B. Garcia, Martin W. McIntosh, Julia Salzman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e37108 (2012)
PLoS ONE, Vol 7, Iss 5, p e37108 (2012)
To what extent might the regulation of translation contribute to differentiation programs, or to the molecular pathogenesis of cancer? Pre-B cells transformed with the viral oncogene v-Abl are suspended in an immortalized, cycling state that mimics l