Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jamie E. McInturff"'
Autor:
Marissa H. Braff, Robert L. Modlin, Anna Di Nardo, Kristen R. Taylor, ChangRim Na, Richard D. Granstein, Jamie E. McInturff, Richard L. Gallo, Stephan R. Krutzik
Publikováno v:
The Journal of Immunology. 178:1829-1834
Cathelicidins are antimicrobial peptides of the innate immune system that establish an antimicrobial barrier at epithelial interfaces and have been proposed to have a proinflammatory function. We studied the role of cathelicidin in allergic contact d
Autor:
Jamie E. McInturff, Jenny Kim
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 3:75-80
Because upregulation of Toll-like receptor (TLR) expression has been observed in some skin diseases, the modulation of TLR function is an elegant therapeutic strategy. The TLR agonist imiquimod has already established utility in treating cutaneous vi
Autor:
Karin Zeh, Robert L. Modlin, Cheryl J. Hertz, Shyh-Jeun Wang, Richard L. Gallo, T. Richard Lin, Daniel H. Anderson, Thomas Machleidt, Scott A. Hart, Jamie E. McInturff, Ami Oren, Jenny Kim, Stephan R. Krutzik
Publikováno v:
Journal of Investigative Dermatology. 125:256-263
Propionibacterium acnes is a key therapeutic target in acne, yet this bacterium has become resistant to standard antibiotic agents. We investigated whether the human antimicrobial protein granulysin is a potential candidate for the treatment of acne.
Publikováno v:
Journal of Investigative Dermatology. 125(1):1-8
Toll-like receptors (TLR) are crucial players in the innate immune response to microbial invaders. These receptors are expressed on immune cells, such as monocytes, macrophages, dendritic cells, and granulocytes. Importantly, TLR are not only express
Autor:
Jenny Kim, Jamie E. McInturff
Publikováno v:
Seminars in Cutaneous Medicine and Surgery. 24:73-78
Acne vulgaris is a common cutaneous disorder of the pilosebaceous follicle, affecting more than 45 million people in the United States alone. The pathogenesis of acne is multifactorial, involving abnormal hyperkeratinization, increased sebum producti