Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jamie E. Fegan"'
Autor:
Jamie E. Fegan, Regula C. Waeckerlin, Liyuwork Tesfaw, Epshita A. Islam, Getaw Deresse, Dawit Dufera, Eyob Assefa, Wubet Woldemedhin, Abinet Legesse, Mirtneh Akalu, Berecha Bayissa, Quynh Huong Nguyen, Dixon Ng, Sang Kyun Ahn, Anthony B. Schryvers, Takele A. Tefera, Trevor F. Moraes, Scott D. Gray-Owen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPasteurella multocida is a bacterial pathogen that causes a variety of infections across diverse animal species, with one of the most devastating associated diseases being hemorrhagic septicemia. Outbreaks of hemorrhagic septicemia in cattl
Externí odkaz:
https://doaj.org/article/db111532093946448a33dc7edaa8c349
Autor:
Thomas J. Bateman, Megha Shah, Timothy Pham Ho, Hyejin Esther Shin, Chuxi Pan, Greg Harris, Jamie E. Fegan, Epshita A. Islam, Sang Kyun Ahn, Yogesh Hooda, Scott D. Gray-Owen, Wangxue Chen, Trevor F. Moraes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nutrient acquisition is crucial for the growth of pathogens within their hosts. Here, Bateman et al. identify a set of proteins required for heme uptake from host hemoglobin and serum albumin in the pathogen Acinetobacter baumannii.
Externí odkaz:
https://doaj.org/article/f80f4a568d8744c5b4768aa9ef00b6d1
Autor:
Jamie E. Fegan, Charles Calmettes, Epshita A. Islam, Sang Kyun Ahn, Somshukla Chaudhuri, Rong-hua Yu, Scott D. Gray-Owen, Trevor F. Moraes, Anthony B. Schryvers
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The surface transferrin receptor proteins from Neisseria gonorrhoeae have been recognized as ideal vaccine targets due to their critical role in survival in the human male genitourinary tract. Recombinant forms of the surface lipoprotein component of
Externí odkaz:
https://doaj.org/article/eb42652bd6064b069b91509da258e22d
Autor:
Megha Shah, Hyejin Esther Shin, Thomas J. Bateman, Yogesh Hooda, Trevor F. Moraes, Timothy Pham Ho, Jamie E. Fegan, Scott D. Gray-Owen, Greg Harris, Wangxue Chen, Chuxi Pan, Sang Kyun Ahn, Epshita A. Islam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Nutrient acquisition systems are often crucial for pathogen growth and survival during infection, and represent attractive therapeutic targets. Here, we study the protein machinery required for heme uptake in the opportunistic pathogen Acinetobacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144242225d95753c17c99742a1d5a0c3
https://doaj.org/article/f80f4a568d8744c5b4768aa9ef00b6d1
https://doaj.org/article/f80f4a568d8744c5b4768aa9ef00b6d1
Autor:
Epshita A. Islam, Jamie E. Fegan, Takele A. Tefera, David M. Curran, Regula C. Waeckerlin, Dixon Ng, Sang Kyun Ahn, Chun Heng Royce Lai, Quynh Huong Nguyen, Megha Shah, Liyuwork Tesfaw, Kassaye Adamu, Wubet W. Medhin, Abinet Legesse, Getaw Deresse, Belayneh Getachew, Neil Rawlyk, Brock Evans, Andrew Potter, Anthony B. Schryvers, Scott D. Gray-Owen, Trevor F. Moraes
Publikováno v:
PLOS Pathogens. 19:e1011249
Pasteurella multocida can infect a multitude of wild and domesticated animals, with infections in cattle resulting in hemorrhagic septicemia (HS) or contributing to bovine respiratory disease (BRD) complex. Current cattle vaccines against P. multocid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5829500d276adbe9e56ab0fddae14ae9
https://doi.org/10.1371/journal.ppat.1011249
https://doi.org/10.1371/journal.ppat.1011249
Autor:
Jamie E. Fegan, Nikolas F. Ewasechko, Luisa Samaniego-Barron, Somshukla Chaudhuri, Anthony B. Schryvers
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618998
Metal ion transporters in the outer membrane of gram-negative bacteria that are responsible for acquiring iron and zinc are attractive vaccine targets due to their essential function. The core function is mediated by an integral outer membrane TonB-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b995988a24e04fa914521b8aa34d2f1
https://doi.org/10.1007/978-1-0716-1900-1_8
https://doi.org/10.1007/978-1-0716-1900-1_8
Autor:
Somshukla, Chaudhuri, Nikolas F, Ewasechko, Luisa, Samaniego-Barron, Jamie E, Fegan, Anthony B, Schryvers
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2414
Metal ion transporters in the outer membrane of gram-negative bacteria that are responsible for acquiring iron and zinc are attractive vaccine targets due to their essential function. The core function is mediated by an integral outer membrane TonB-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd59e21191cf8b919889c6ac153c815f
https://pubmed.ncbi.nlm.nih.gov/34784035
https://pubmed.ncbi.nlm.nih.gov/34784035
Autor:
Trevor F. Moraes, Charles Calmettes, Steven Ahn, Epshita A. Islam, Anthony B. Schryvers, Rong-hua Yu, Jamie E. Fegan, Scott D. Gray-Owen
Publikováno v:
Oral Presentations.
Background The bacterial transferrin receptor has long been considered an outstanding vaccine target against pathogenic Neisseria species as it is surface-exposed and essential for bacterial survival and virulence in vivo. Required for iron uptake fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a443b8d38e5ffcd7db44633903aaf4
https://doi.org/10.1136/sextrans-2019-sti.106
https://doi.org/10.1136/sextrans-2019-sti.106
Publikováno v:
J Immunol Methods
Traditional ELISA-based protein analysis has been predicated on the assumption that proteins bind randomly to the solid surface of the ELISA plate polymer (polystyrene or polyvinyl chloride). Random adherence to the plate ensures equal access to all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c44e5a37abb28d29f732864a0fd619
https://doi.org/10.1016/j.jim.2021.113037
https://doi.org/10.1016/j.jim.2021.113037
Autor:
Bibiana Martins Barasuol, Luiz Carlos Kreutz, Anthony B. Schryvers, Rafael Frandoloso, Elías F. Rodríguez-Ferri, César B. Gutiérrez-Martín, Jamie E. Fegan, João Antônio Guizzo, Sonia Martínez-Martínez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Vaccines have become fundamental in the control and elimination of Glässer Disease, a systemic disease of pigs caused by Haemophilus parasuis. The classic vaccines available for prevention of this infection were developed without a robust knowledge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72afccf0cf6db0eb7b7fa108126072d
https://doi.org/10.1038/s41598-017-10627-0
https://doi.org/10.1038/s41598-017-10627-0