Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jamie E Mangold"'
Autor:
Ming D Li, Jamie E Mangold, Chamindi Seneviratne, Guo-Bo Chen, Jennie Z Ma, Xiang-Yang Lou, Thomas J Payne
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7055 (2009)
Previous studies have demonstrated that the gamma-aminobutyric acid type B (GABA(B)) receptor plays an essential role in modulating neurotransmitter release and regulating the activity of ion channels and adenyl cyclase. However, whether the naturall
Externí odkaz:
https://doaj.org/article/7cc7dcf5e8f2425ea20f73031726f073
Autor:
Maria A. Mariggiò, Elizabeth A. Jonas, Armando P. Signore, Hongmei Li, Laura Bonanni, Panah Nabili, Ulrike Demarco, Jamie E. Mangold, Ping Zhang, Damon R. Demady, Steven I. Dworetzky, Peter K. Smith, Kambiz N. Alavian, Emma Lazrove, Valentin K. Gribkoff, Marco Onofrj, Silvio Sacchetti, Astrid Thomas
Publikováno v:
BASE-Bielefeld Academic Search Engine
Cellular stress or injury can result in mitochondrial dysfunction, which has been linked to many chronic neurological disorders including amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). Stressed and dysfunctional mitochondria exhi
Autor:
Jinxue Wei, Junran Cao, Jennifer B. Dwyer, Ju Wang, Jamie E. Mangold, Frances M. Leslie, Ming D. Li
Publikováno v:
International Journal of Neuropsychopharmacology. 14:157-174
Maternal smoking during pregnancy (MS) has long-lasting neurobehavioural effects on the offspring. Many MS-associated psychiatric disorders begin or change symptomatology during adolescence, a period of continuous development of the central nervous s
Autor:
Jamie E. Mangold, Jinxue Wei, Ju Wang, Frances M. Leslie, Junran Cao, Jennifer B. Dwyer, Ming D. Li
Publikováno v:
International Journal of Neuropsychopharmacology. 14:91-106
Gestational exposure to nicotine affects brain development, leading to numerous behavioural and physiological deficits in the offspring during adolescence. To analyse the molecular mechanisms underlying these effects, a pathway-focused oligonucleotid
Autor:
David L. Hill, Jamie E. Mangold
Publikováno v:
The Journal of Neuroscience. 27:4650-4662
Neural development is especially vulnerable to environmental influences during periods of neurogenesis and rapid maturation. In fact, short periods of environmental manipulations confined to embryonic development lead to significant changes in morpho
Autor:
Jamie E. Mangold, David L. Hill
Publikováno v:
The Journal of comparative neurology. 509(6)
Dietary manipulation has been used as an experimental strategy to gain insight into the normal development of the gustatory system. Institution of a diet low in sodium chloride (NaCl) from embryonic day 3 (E3) to E12 (E3-E12 sodium-restricted rats) y
Publikováno v:
Journal of medical genetics. 45(9)
Context: Bitter sensitivity varies among individuals and ethnic groups partly due to polymorphisms in taste receptor genes (TAS2Rs). Although previous psychophysical studies suggest that taste status plays a role in nicotine dependence (ND), genetic
Autor:
Laura Bonanni, Ping Zhang, Kambiz N. Alavian, Steven I. Dworetzky, Peter K. Smith, Elizabeth A. Jonas, Uli DeMarco, Jamie E. Mangold, Valentin K. Gribkoff, Silvio Sacchetti, Armando P. Signore
Publikováno v:
ResearcherID
Chronic neurodegenerative disorders have been linked to mitochondrial dysfunction. Pharmaceutical agents which reduce mitochondrial dysfunction may provide therapeutic benefit by protecting neurons at risk. In the current study we have investigated t
Autor:
Jennie Z. Ma, Guo-Bo Chen, Chamindi Seneviratne, Ming D. Li, Thomas J. Payne, Xiang-Yang Lou, Jamie E. Mangold
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e7055 (2009)
PLoS ONE, Vol 4, Iss 9, p e7055 (2009)
Previous studies have demonstrated that the gamma-aminobutyric acid type B (GABA(B)) receptor plays an essential role in modulating neurotransmitter release and regulating the activity of ion channels and adenyl cyclase. However, whether the naturall
Autor:
Jennie Z. Ma, Robert C. Elston, Xiang-Yang Lou, Lei Yan, Guo-Bo Chen, Ming D. Li, Jun Zhu, Jamie E. Mangold
Publikováno v:
The American Journal of Human Genetics. (4):457-467
Widespread multifactor interactions present a significant challenge in determining risk factors of complex diseases. Several combinatorial approaches, such as the multifactor dimensionality reduction (MDR) method, have emerged as a promising tool for