Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jamie A. Morrison"'
Autor:
Andrés de la Rosa, Nicole G. Metzendorf, Jamie I. Morrison, Rebecca Faresjö, Fadi Rofo, Alex Petrovic, Paul O’Callaghan, Stina Syvänen, Greta Hultqvist
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The blood–brain barrier (BBB) greatly limits the delivery of protein-based drugs into the brain and is a major obstacle for the treatment of brain disorders. Targeting the transferrin receptor (TfR) is a strategy for transporting protein-b
Externí odkaz:
https://doaj.org/article/aa4b075b0c2048ffaa30444b0494af4a
Autor:
Jamie I. Morrison, Alex Petrovic, Nicole G. Metzendorf, Fadi Rofo, Canan U. Yilmaz, Sofia Stenler, Hanna Laudon, Greta Hultqvist
Publikováno v:
Molecular Pharmaceutics. 20:1564-1576
Publikováno v:
Journal of Neurochemistry. 165:413-425
Autor:
Aikaterini Chourlia, Jamie I. Morrison, Fadi Rofo, Friederike A. Sandbaumhüter, Greta Hultqvist, Erik T. Jansson, Nicole G. Metzendorf, Stina Syvänen, Per E. Andrén
Publikováno v:
ACS Chemical Neuroscience
Alzheimer’s disease is the most common neurodegenerative disorder characterized by the pathological aggregation of amyloid-β (Aβ) peptide. A potential therapeutic intervention in Alzheimer’s disease is to enhance Aβ degradation by increasing t
Autor:
Jamie I. Morrison, Alex Petrovic, Nicole G. Metzendorf, Fadi Rofo, Canan U. Yilmaz, Sofia Stenler, Hanna Laudon, Greta Hultqvist
The presence of the blood brain barrier (BBB) creates a nigh on impenetrable obstacle for large macromolecular therapeutics that need to be delivered to the brain milieu to treat neurological disorders. To overcome this, one of the strategies used is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c49297b4a4fcefbfaa2a8dfb9b3895b
https://doi.org/10.21203/rs.3.rs-1527031/v2
https://doi.org/10.21203/rs.3.rs-1527031/v2
Autor:
Fadi Rofo, Silvio R. Meier, Nicole G. Metzendorf, Jamie I. Morrison, Alex Petrovic, Stina Syvänen, Dag Sehlin, Greta Hultqvist
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 19(5)
Amyloid-β (Aβ) oligomers and protofibrils are suggested to be the most neurotoxic Aβ species in Alzheimer’s disease (AD). Hence, antibodies with strong and selective binding to these soluble Aβ aggregates are of therapeutic potential. We have r
Autor:
Eileen T. Kennedy, Maximo A. Torero, Dariush Mozaffarian, William A. Masters, Roy A. Steiner, Sheryl L. Hendriks, Jamie A. Morrison, Kathleen A. Merrigan, Shibani A. Ghosh, Daniel E. Mason-d’Croz
Publikováno v:
Current Developments in Nutrition. 7:100028
Autor:
Mark Sutton-Smith, Manish S. Patankar, Howard R. Morris, Nyet Kui Wong, Richard L. Easton, Jamie C. Morrison, Gary F. Clark, Anne Dell, Frank A. Lattanzio, Maria Panico
Publikováno v:
Journal of Biological Chemistry. 278:28619-28634
CA125 is a mucin commonly employed as a diagnostic marker for epithelial ovarian cancer. Induction of humoral responses to CA125 leads to increased survival times in patients with this form of cancer, suggesting a potential role for this mucin in tum
Autor:
Yuping Deng, Anne Dell, Yu Jing, Jennifer A. Belisle, Howard R. Morris, Nyet Kui Wong, Jamie C. Morrison, Frank A. Lattanzio, Gary F. Clark, Manish S. Patankar
Publikováno v:
Gynecologic oncology. 99(3)
Objectives. CA125 expresses specific oligosaccharides that can inhibit the cytotoxicity of human natural killer (NK) cells. The current study was undertaken to determine the ability of CA125 to modulate NK cell-mediated cytotoxicity. Methods. CA125 w
Autor:
Howard R. Morris, Manish S. Patankar, Gary F. Clark, Richard L. Easton, Sara Chalabi, Jamie C. Morrison, Anne Dell, Maria Panico, Frank A. Lattanzio
Publikováno v:
The Journal of biological chemistry. 277(36)
Human seminal plasma is a complex mixture of proteins, glycoproteins, peptides, glycopeptides, and prostaglandins secreted by organs of the male reproductive tract. The components of this fluid have been implicated in the suppression of immune respon