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pro vyhledávání: '"Jamie, Sly"'
Autor:
Norah A, Owiti, Simran, Kaushal, Lincoln, Martin, Jamie, Sly, Carol D, Swartz, Jasmine, Fowler, Joshua J, Corrigan, Les, Recio, Bevin P, Engelward
Publikováno v:
Current Protocols. 2
Exposure to DNA damaging agents can lead to mutations that cause cancer. The liver is particularly vulnerable because it contains high levels of Cytochrome P450 enzymes that can convert xenobiotics into DNA reactive metabolites that form potentially
Autor:
Kamala, Pant, Shannon, Bruce, Jamie, Sly, Michelle, Klug Laforce, Sandra, Springer, Mark, Cecil, Edgar, Andrus, Emily, Dakoulas, Valentine O, Wagner, Nicola J, Hewitt, Rohan, Kulkarni
Publikováno v:
Environmental and molecular mutagenesis. 57(6)
Bacterial mutation assays are conducted routinely as part of the safety assessment of new chemicals. The OECD Test Guideline (TG) 471 describes the conduct of the standard agar plate Ames assay, required for regulatory submissions. Higher throughput