Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jami L. Saloman"'
Publikováno v:
Journal of Pancreatology, Vol 7, Iss 1, Pp 35-44 (2024)
Abdominal pain is the most common symptom of chronic pancreatitis (CP) and is often debilitating for patients and very difficult to treat. To date, there exists no cure for the disease. Treatment strategies focus on symptom management and on mitigati
Externí odkaz:
https://doaj.org/article/f4534a9af10c4261bac231a56373d090
Autor:
Adam Slivka, Rohit Das, Asbjørn Mohr Drewes, Søren Schou Olesen, Mouen A Khashab, Vikesh K Singh, Dhiraj Yadav, Mahya Faghih, Anna Evans Phillips, Elham Afghani, Venkata Sandeep Akshintala, Panayiotis Y Benos, Jeffrey Easler, Charles Gabbert, Vivek Halappa, Jami L Saloman, Biatta Sholosh, Tianxiu Wang
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Treatment for abdominal pain in patients with chronic pancreatitis (CP) remains challenging in the setting of central nervous system sensitisation, a phenomenon of remodelling and neuronal hyperexcitability resulting from persistent pain
Externí odkaz:
https://doaj.org/article/e4cd25da4e174f66bf5ed04a09297663
Autor:
Ranjeet S. Kalsi, Alexander M. Kreger, Mohamed Saleh, Shiho Yoshida, Kartikeya Sharma, Joseph Fusco, Jami L. Saloman, Ting Zhang, Madison Thomas, Anuradha Sehrawat, Yan Wang, Jason Reif, Juliana Mills, Sarah Raad, Bugra Zengin, Ana Gomez, Aatur Singhi, Sameh Tadros, Adam Slivka, Farzad Esni, Krishna Prasadan, George Gittes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Chronic pancreatitis is a debilitating disease affecting millions worldwide. These patients suffer from bouts of severe pain that are minimally relieved by pain medications and may necessitate major surgeries with high morbidity and mortalit
Externí odkaz:
https://doaj.org/article/02b91bf8bc944deea70bf733168b753b
Autor:
Samuel Han, Darwin L. Conwell, Liang Li, Alejandra Cervantes, Phil A. Hart, Zobeida Cruz-Monserrate, Wenrui Hao, Gregory B. Lesinski, Thomas Mace, Tonya M. Palermo, Jami L. Saloman, Dhiraj Yadav, Santhi Swaroop Vege, Mark Topazian
Publikováno v:
Pancreatology. 23:42-47
Current treatments for chronic pancreatitis focus on symptom management and therapeutics targeting disease reversal are lacking. Given the role of the cyclooxygenase-2 (COX-2) enzyme in producing prostaglandin EThis pilot two-center randomized contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c3a976e36d4a05ed50e658df444ce3
https://doi.org/10.1016/j.pan.2022.12.008
https://doi.org/10.1016/j.pan.2022.12.008
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The incidence of pain in cancer patients during diagnosis and treatment is exceedingly high. Although advances in cancer detection and therapy have improved patient prognosis, cancer and its treatment-associated pain have gained clinical prominence.
Externí odkaz:
https://doaj.org/article/c2c23da2763d4e33a30bdcdb4dc71a43
Autor:
Kimberly A. Meerschaert, Brian S. Edwards, Ariel Y. Epouhe, Bahiyyah Jefferson, Robert Friedman, Olivia L. Babyok, Jamie K. Moy, Faith Kehinde, Chang Liu, Creg J. Workman, Dario A.A. Vignali, Kathryn M. Albers, H. Richard Koerber, Michael S. Gold, Brian M. Davis, Nicole N. Scheff, Jami L. Saloman
Publikováno v:
Brain, Behavior, and Immunity. 106:233-246
PDL1 is a protein that induces immunosuppression by binding to PD1 expressed on immune cells. In line with historical studies, we found that membrane-bound PD1 expression was largely restricted to immune cells; PD1 was not detectable at either the mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b68dfbd6b4215fe549c1e79db8e944
https://doi.org/10.1016/j.bbi.2022.09.001
https://doi.org/10.1016/j.bbi.2022.09.001
Autor:
Jami L, Saloman, Darwin L, Conwell, Evan, Fogel, Santhi Swaroop, Vege, Liang, Li, Shuang, Li, Dana K, Andersen, William E, Fisher, Christopher E, Forsmark, Phil A, Hart, Stephen J, Pandol, Walter G, Park, Anna Evans, Phillips, Mark, Topazian, Stephen K, Van Den Eeden, Jose, Serrano, Dhiraj, Yadav
Publikováno v:
Pain. 164:375-384
Pain is common in chronic pancreatitis (CP) and profoundly reduces quality of life (QoL). Multiple underlying mechanisms contribute to a heterogenous pain experience and reduce efficacy of pain management. This study was designed to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b54dabe33e2cd78db4fa9721ec81b1
https://doi.org/10.1097/j.pain.0000000000002710
https://doi.org/10.1097/j.pain.0000000000002710
Publikováno v:
The Journal of Pain. 24:2-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d0229d537650e333d8746cfd285b759
https://doi.org/10.1016/j.jpain.2023.02.012
https://doi.org/10.1016/j.jpain.2023.02.012
Autor:
Gwendolyn Sowa, Asbjørn Mohr Drewes, A. Vania Apkarian, Tonya M. Palermo, Aliye Uc, Pankaj J. Pasricha, Chris E. Forsmark, Sarah Jane Schwarzenberg, Leonardo Kapural, Thomas B. Strouse, Ellyn K Dunbar, John A. Windsor, Luana Colloca, Dana K. Andersen, Stephen J. Pandol, George F. Koob, Marc T. Goodman, Jami L. Saloman, Anna E. Phillips, Glenn J. Treisman, Melena D. Bellin, Vikesh K. Singh, Dhiraj Yadav, Daniele Piomelli
Publikováno v:
Pancreas
Uc, A, Andersen, D K, Apkarian, A V, Bellin, M D, Colloca, L, Drewes, A M, Dunbar, E K, Forsmark, C E, Goodman, M T, Kapural, L, Koob, G F, Palermo, T M, Pandol, S J, Pasricha, P, Phillips, A E, Piomelli, D, Saloman, J L, Schwarzenberg, S J, Singh, V K, Sowa, G, Strouse, T, Treisman, G J, Windsor, J A & Yadav, D 2021, ' Pancreatic Pain-Knowledge Gaps and Research Opportunities in Children and Adults : Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop ', Pancreas, vol. 50, no. 7, pp. 906-915 . https://doi.org/10.1097/MPA.0000000000001899
Uc, A, Andersen, D K, Apkarian, A V, Bellin, M D, Colloca, L, Drewes, A M, Dunbar, E K, Forsmark, C E, Goodman, M T, Kapural, L, Koob, G F, Palermo, T M, Pandol, S J, Pasricha, P, Phillips, A E, Piomelli, D, Saloman, J L, Schwarzenberg, S J, Singh, V K, Sowa, G, Strouse, T, Treisman, G J, Windsor, J A & Yadav, D 2021, ' Pancreatic Pain-Knowledge Gaps and Research Opportunities in Children and Adults : Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop ', Pancreas, vol. 50, no. 7, pp. 906-915 . https://doi.org/10.1097/MPA.0000000000001899
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities in pancreatic pain. The event was held on July 21, 2021, and structured into 4 sessions: (1) pathophysiology;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c0292ab7a820c3b485b73f8f8a5ff3
https://doi.org/10.1097/mpa.0000000000001899
https://doi.org/10.1097/mpa.0000000000001899
Publikováno v:
Journal of Pain Research
Pain is the most distressing and disruptive feature of recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) resulting in low quality of life (QOL) and disabilities. There is no single, characteristic pain pattern in patients with RAP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa951ee67feaf4d8e972d31c7570dc6f
https://doi.org/10.2147/jpr.s274276
https://doi.org/10.2147/jpr.s274276