Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Jamey P Weichert"'
Autor:
Douglas G McNeel, Zachary S Morris, Reinier Hernandez, Jamey P Weichert, Anusha Muralidhar, Hansel Comas Rojas, Malick Bio Idrissou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Rationale Androgen deprivation therapy (ADT) is pivotal in treating recurrent prostate cancer and is often combined with external beam radiation therapy (EBRT) for localized disease. However, for metastatic castration-resistant prostate cancer, EBRT
Externí odkaz:
https://doaj.org/article/27673128e2c04b24a1157868424e0536
Autor:
Zachary S Morris, Paul M Sondel, Amy K Erbe, Alexander L Rakhmilevich, Amber M Bates, Peter M Carlson, Alexander A Pieper, Ravi B Patel, Jen Birstler, Joseph Grudzinski, Reinier Hernandez, Bryan P Bednarz, Jamey P Weichert, Arika S Feils, Matthew Rodriquez, Claire Sun, Ian Marsh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background The antitumor effects of external beam radiation therapy (EBRT) are mediated, in part, by an immune response. We have reported that a single fraction of 12 Gy EBRT combined with intratumoral anti-GD2 hu14.18-IL2 immunocytokine (IC) generat
Externí odkaz:
https://doaj.org/article/1ef1a1af9237404b8526eb674951b943
Autor:
Douglas G McNeel, Hemanth K Potluri, Ohyun Kwon, Joseph Grudzinski, Christopher Massey, Reinier Hernandez, Carolina A Ferreira, Eduardo Aluicio-Sarduy, Jonathan W Engle, Ian R Marsh, Bryan P Bednarz, Jamey P Weichert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background Systemic radiation treatments that preferentially irradiate cancer cells over normal tissue, known as targeted radionuclide therapy (TRT), have shown significant potential for treating metastatic prostate cancer. Preclinical studies have d
Externí odkaz:
https://doaj.org/article/385680f3c7034b26aee4d0c6c0c3d464
Autor:
Kara Magee, Ian R Marsh, Michelle M Turek, Joseph Grudzinski, Eduardo Aluicio-Sarduy, Jonathan W Engle, Ilene D Kurzman, Cindy L Zuleger, Elizabeth A Oseid, Christine Jaskowiak, Mark R Albertini, Karla Esbona, Bryan Bednarz, Paul M Sondel, Jamey P Weichert, Zachary S Morris, Reinier Hernandez, David M Vail
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255798 (2021)
RationaleMurine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the sa
Externí odkaz:
https://doaj.org/article/614577853cda400990756e8aa63b13c4
Autor:
Dustin A Deming, Molly E Maher, Alyssa A Leystra, Joseph P Grudzinski, Linda Clipson, Dawn M Albrecht, Mary Kay Washington, Kristina A Matkowskyj, Lance T Hall, Sam J Lubner, Jamey P Weichert, Richard B Halberg
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109668 (2014)
The treatment of localized colorectal cancer (CRC) depends on resection of the primary tumor with adequate margins and sufficient lymph node sampling. A novel imaging agent that accumulates in CRCs and the associated lymph nodes is needed. Cellectar
Externí odkaz:
https://doaj.org/article/d90497f5ff9945f6b8b2860f54bd5187
Autor:
Joseph J Grudzinski, Benjamin Titz, Kevin Kozak, William Clarke, Ernest Allen, LisaAnn Trembath, Michael Stabin, John Marshall, Steve Y Cho, Terence Z Wong, Joanne Mortimer, Jamey P Weichert
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111652 (2014)
(131)I-CLR1404 is a small molecule that combines a tumor-targeting moiety with a therapeutic radioisotope. The primary aim of this phase 1 study was to determine the administered radioactivity expected to deliver 400 mSv to the bone marrow. The secon
Externí odkaz:
https://doaj.org/article/ae0c07991e9f4267a6e5992329319c15
Autor:
Dustin A Deming, Alyssa A Leystra, Mohammed Farhoud, Laura Nettekoven, Linda Clipson, Dawn Albrecht, Mary Kay Washington, Ruth Sullivan, Jamey P Weichert, Richard B Halberg
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60709 (2013)
The phosphatidylinositide-3-kinase (PI3K) signaling pathway is critical for multiple cellular functions including metabolism, proliferation, angiogenesis, and apoptosis, and is the most commonly altered pathway in human cancers. Recently, we develope
Externí odkaz:
https://doaj.org/article/d31eff1ed832492ba8863e2f9091656e
Autor:
Ian R. Marsh, Chunrong Li, Joseph Grudzinski, Justin Jeffery, Colin Longhurst, David P. Adam, Reinier Hernandez, Jamey P. Weichert, Paul M. Harari, Bryan P. Bednarz
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31ad178d8bbb973af5f4603bbb967c20
https://doi.org/10.1089/cbr.2022.0084
https://doi.org/10.1089/cbr.2022.0084
Autor:
Mario Otto, Gopal Iyer, Paul M. Harari, Bryan P. Bednarz, Eric A. Armstrong, Jamey P. Weichert, Lance T. Hall, Sorabh Singhal, Lauryn R. Werner, Chunrong Li, Dana C. Baiu, Albert R. Wang, Ankita Shahi, Mohamed Y. Elsaid
Supplementary Table 1. List of Antibodies used for Western and IHC. Supplementary Table 2. Plating efficiency (clonogenic assay). Supplementary Table 3. Statistical analysis of tumor growth rates in xenograft experiments (linear mixed effects model w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8c46e84296f62c1b7ffdf006ac8dc7
https://doi.org/10.1158/1535-7163.22504858
https://doi.org/10.1158/1535-7163.22504858
Autor:
Mario Otto, Gopal Iyer, Paul M. Harari, Bryan P. Bednarz, Eric A. Armstrong, Jamey P. Weichert, Lance T. Hall, Sorabh Singhal, Lauryn R. Werner, Chunrong Li, Dana C. Baiu, Albert R. Wang, Ankita Shahi, Mohamed Y. Elsaid
Antitumor alkyl phospholipid (APL) analogs comprise a group of structurally related molecules with remarkable tumor selectivity. Some of these compounds have shown radiosensitizing capabilities. CLR127 is a novel, clinical-grade antitumor APL ether a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b8d04632726f16eeb76d6bcb6d09a23
https://doi.org/10.1158/1535-7163.c.6537874.v1
https://doi.org/10.1158/1535-7163.c.6537874.v1