Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Jamey D Young"'
Autor:
Courtney A Copeland, Benjamin A Olenchock, David Ziehr, Sarah McGarrity, Kevin Leahy, Jamey D Young, Joseph Loscalzo, William M Oldham
Publikováno v:
eLife, Vol 12 (2023)
Hypoxia requires metabolic adaptations to sustain energetically demanding cellular activities. While the metabolic consequences of hypoxia have been studied extensively in cancer cell models, comparatively little is known about how primary cell metab
Externí odkaz:
https://doaj.org/article/22d0346cf34a4f7eae272e08bef916d3
Autor:
Clinton M Hasenour, Martha L Wall, D Emerson Ridley, Freyja D James, Curtis C Hughey, E Patrick Donahue, Benoit Viollet, Marc Foretz, Jamey D Young, David H Wasserman
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183601 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0170382.].
Externí odkaz:
https://doaj.org/article/d354663b96f6454c8c652e11dd6eaeac
Autor:
Clinton M Hasenour, D Emerson Ridley, Freyja D James, Curtis C Hughey, E Patrick Donahue, Benoit Viollet, Marc Foretz, Jamey D Young, David H Wasserman
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170382 (2017)
AMPK is an energy sensor that protects cellular energy state by attenuating anabolic and promoting catabolic processes. AMPK signaling is purported to regulate hepatic gluconeogenesis and substrate oxidation; coordination of these processes is vital
Externí odkaz:
https://doaj.org/article/80c12fbc0933474e984e7517decadd1a
Autor:
Anna Hemnes, Niki Fortune, Katie Simon, Irina A. Trenary, Sheila Shay, Eric Austin, Jamey D. Young, Evan Britain, James West, Megha Talati
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundIn PAH metabolic abnormalities in multiple pathways are well-recognized features of right ventricular dysfunction, however, prior work has focused mainly on the use of a single “omic” modality to describe a single deranged pathway. We i
Externí odkaz:
https://doaj.org/article/22d6d48498684b8396f4cc91e68694e9
Autor:
Yasushi Noguchi, Natsumi Nishikata, Nahoko Shikata, Yoshiko Kimura, Jose O Aleman, Jamey D Young, Naoto Koyama, Joanne K Kelleher, Michio Takahashi, Gregory Stephanopoulos
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12057 (2010)
Although dietary ketogenic essential amino acid (KAA) content modifies accumulation of hepatic lipids, the molecular interactions between KAAs and lipid metabolism are yet to be fully elucidated.We designed a diet with a high ratio (E/N) of essential
Externí odkaz:
https://doaj.org/article/de34305f19f94c3d929c6dae229c047c
Autor:
Bo Wang, Jamey D. Young
Publikováno v:
Analytical Chemistry. 94:7787-7794
Autor:
Sarah A. Sacco, Angela M. Tuckowski, Irina Trenary, Lauren Kraft, Michael J. Betenbaugh, Jamey D. Young, Kevin D. Smith
Publikováno v:
Biotechnology and Bioengineering. 119:1712-1727
The glutamine synthetase (GS) expression system is commonly used to ensure stable transgene integration and amplification in Chinese hamster ovary (CHO) host lines. Transfected cell populations are typically grown in the presence of the GS inhibitor,
Autor:
Gaurav Sharma, Nesmine Maptue, Mohsin Rahim, Miriam L. Trigo Mijes, Thomas Hever, Xiaodong Wen, Alexander M. Funk, Craig R. Malloy, Jamey D. Young, Chalermchai Khemtong
Publikováno v:
NMR in Biomedicine. 36
Publikováno v:
Current Opinion in Biotechnology. 71:1-8
Identifying the factors and mechanisms that regulate metabolism under normal and diseased states requires methods to quantify metabolic fluxes of live tissues within their physiological milieu. A number of recent developments have expanded the reach
Autor:
Gaurav Sharma, Nesmine Maptue, Mohsin Rahim, Miriam L. Trigo Mijes, Thomas Hever, Xiaodong Wen, Alexander M. Funk, Craig R. Malloy, Jamey D. Young, Chalermchai Khemtong
Publikováno v:
NMR in Biomedicine. 36