Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jameson T. Crowley"'
Autor:
Alvaro Toledo, Jameson T. Crowley, James L. Coleman, Timothy J. LaRocca, Salvatore Chiantia, Erwin London, Jorge L. Benach
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Borrelia burgdorferi contains unique cholesterol-glycolipid-rich lipid rafts that are associated with lipoproteins. These complexes suggest the existence of macromolecular structures that have not been reported for prokaryotes. Outer surface
Externí odkaz:
https://doaj.org/article/c93f466388814badbe034779d2a066b9
Autor:
Sheila L. Arvikar, Elise E. Drouin, Annalisa Pianta, Klemen Strle, Jameson T. Crowley, Allen C. Steere, Catherine E. Costello
Publikováno v:
Clinical Immunology. 160:336-341
In this study, autoantibody responses to annexin A2 were found in 11-15% of 278 patients with Lyme disease, including in those with erythema migrans (EM), an early sign of the illness, and in those with antibiotic-responsive or antibiotic-refractory
Autor:
Allen C. Steere, Elise E. Drouin, Catherine E. Costello, Klemen Strle, Jameson T. Crowley, Annalisa Pianta, Qi Wang
Publikováno v:
Journal of Infectious Diseases. 212:1841-1850
To discover novel autoantigens associated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte antigen (HLA)-DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope for autorea
Autor:
Robert B. Lochhead, Katherine B. Sulka, Jameson T. Crowley, Allen C. Steere, Klemen Strle, Robert M. Anthony
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(11)
Objective To determine whether IgG subclasses of Borrelia burgdorferi antibodies differ from those of 3 Lyme disease (LD)-associated autoantibodies. Methods IgG antibody subclasses were determined by enzyme-linked immunosorbent assay in serum samples
Publikováno v:
Molecular Microbiology. 88:619-633
Summary Borrelia burgdorferi, the spirochaetal agent of Lyme disease, codes for a single HtrA protein, HtrABb (BB0104) that is homologous to DegP of Escherichia coli (41% amino acid identity). HtrABb shows physical and biochemical similarities to Deg
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(1)
Objective To describe systemic autoimmune joint diseases that develop following Lyme disease, and to compare their clinical features with those of Lyme arthritis (LA). Methods We reviewed records of all adult patients referred to our LA clinic over a
Autor:
Allen C. Steere, Qi Wang, Elise E. Drouin, Klemen Strle, Sheila L. Arvikar, Jameson T. Crowley, Annalisa Pianta, Catherine E. Costello
Infection-induced autoimmunity is thought to be a contributing factor in antibiotic-refractory Lyme arthritis, but studies of autoimmunity have been hindered by difficulty in identifying relevant auto-antigens. We developed a novel approach that begi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d140b4d210f0d5a184e70909f0a37070
https://europepmc.org/articles/PMC4826816/
https://europepmc.org/articles/PMC4826816/
Autor:
Jorge L. Benach, Juan Carlos Garcia-Monco, Jordi Benach, Timothy J. LaRocca, Brian J. Cusack, Erwin London, Jameson T. Crowley, Priyadarshini Pathak
Publikováno v:
Cell Host & Microbe. 8:331-342
SummaryBorrelia burgdorferi, the agent of Lyme disease, is unusual as it contains free cholesterol and cholesterol glycolipids. It is also susceptible to complement-independent bactericidal antibodies, such as CB2, a monoclonal IgG1 against outer sur
Autor:
Allen C. Steere, Ruslan I. Sadreyev, Katherine B. Sulka, Jameson T. Crowley, Anthony Anselmo, Sheila L. Arvikar, Annalisa Pianta, Klemen Strle
Publikováno v:
Clinical Infectious Diseases. :cix002
Background Control of Lyme disease is attributed predominantly to innate and adaptive T-helper 1 cell (TH1) immune responses, whereas the role of T-helper 17 cell (TH17) responses is less clear. Here we characterized these inflammatory responses in p
Autor:
James L. Coleman, Jorge L. Benach, Salvatore Chiantia, Jameson T. Crowley, Timothy J. LaRocca, Erwin London, Alvaro Toledo
Publikováno v:
mBio
mBio, Vol 5, Iss 2 (2014)
mBio, Vol 5, Iss 2 (2014)
Borrelia burgdorferi contains unique cholesterol-glycolipid-rich lipid rafts that are associated with lipoproteins. These complexes suggest the existence of macromolecular structures that have not been reported for prokaryotes. Outer surface lipoprot