Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jameson R. Bothe"'
Autor:
Robert Zarnowski, William M. Westler, Ghislain Ade Lacmbouh, Jane M. Marita, Jameson R. Bothe, Jörg Bernhardt, Anissa Lounes-Hadj Sahraoui, Joël Fontaine, Hiram Sanchez, Ronald D. Hatfield, James M. Ntambi, Jeniel E. Nett, Aaron P. Mitchell, David R. Andes
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Virulence of Candida is linked with its ability to form biofilms. Once established, biofilm infections are nearly impossible to eradicate. Biofilm cells live immersed in a self-produced matrix, a blend of extracellular biopolymers, many of w
Externí odkaz:
https://doaj.org/article/b01789ea810348e691a8c1064b7ff2c5
Autor:
Jonathan Fine, Prageeth R. Wijewardhane, Sheik Dawood Beer Mohideen, Katelyn Smith, Jameson R. Bothe, Yogita Krishnamachari, Alexandra Andrews, Yong Liu, Gaurav Chopra
Publikováno v:
Pharmaceutical Research. 40:701-710
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a454ab56fe2f8bddbd4d1c38e5d2da9
https://doi.org/10.1007/s11095-023-03475-3
https://doi.org/10.1007/s11095-023-03475-3
Autor:
Zachary L. VanAernum, Joseph A. Sergi, Monisha Dey, Timothy Toner, Bruce Kilgore, Ashley Lay-Fortenbery, Yi Wang, Shengjie Bian, Brent A. Kochert, Jameson R. Bothe, Xinliu Gao, Douglas Richardson, Hillary A. Schuessler
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2064bfe867df082b936cad3dcb4331ee
https://doi.org/10.1007/s11095-022-03462-0
https://doi.org/10.1007/s11095-022-03462-0
Autor:
Qiang Wang, Nicklas Waterhouse, Olusegun Feyijinmi, Matthew J Dominguez, Lisa M Martinez, Zoey Sharp, Rachel Service, Jameson R Bothe, Elliott J Stollar
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146232 (2016)
The kinetics of folding and unfolding underlie protein stability and quantification of these rates provides important insights into the folding process. Here, we present a simple high throughput protein unfolding kinetic assay using a plate reader th
Externí odkaz:
https://doaj.org/article/9413f6c09b5740f897d2e5ea8418b5c4
Autor:
Scott Burton, Tonya Grunewald, Peter R. Johnson, Mark Tomai, Joan T. Moseman, Jameson R. Bothe, Ronald D. Smith, Mikolaj Milewski, Vinh Hua, Yash Kapoor, Becky Nissley, Kim Manser, Ioan Petrescu, Jingtao Zhang, Michele Gehrt, Dick Lisa
Publikováno v:
Biomedical microdevices. 22(1)
Minimally invasive delivery of peptide and protein molecules represents a significant opportunity for product differentiation and value creation versus standard injectable routes of administration. One such technology utilizes microneedle (MN) patche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdc7b2f3023e2b72ff364855d62bb31
https://pubmed.ncbi.nlm.nih.gov/31845070
https://pubmed.ncbi.nlm.nih.gov/31845070
Autor:
Svetlana Lutsenko, Sergiy Nokhrin, Lelita T. Braiterman, Jameson R. Bothe, Marco Tonelli, Oleg Y. Dmitriev, Nan Yang, Corey H. Yu, Natalia V. Dolgova
Publikováno v:
Journal of Biological Chemistry. 292:18169-18177
The human transporter ATP7B delivers copper to the biosynthetic pathways and maintains copper homeostasis in the liver. Mutations in ATP7B cause the potentially fatal hepatoneurological disorder Wilson disease. The activity and intracellular localiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f62c943dae8d1a2fdb89ba7417ed5fe
https://doi.org/10.1074/jbc.m117.811752
https://doi.org/10.1074/jbc.m117.811752
Autor:
Leo A. Joyce, Yogita Krishnamachari, Alexandra Andrews, Sandhya Kashi, Katelyn J Smith, Jameson R. Bothe
Publikováno v:
Molecular pharmaceutics. 16(5)
Peptides and proteins commonly have complex structural landscapes allowing for transformation into a wide array of species including oligomers, aggregates, and fibrils. The formation of undesirable forms including aggregates and fibrils poses serious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf9b8ed0d6f4c5e7b5a65d7cbff7467
https://pubmed.ncbi.nlm.nih.gov/30990695
https://pubmed.ncbi.nlm.nih.gov/30990695
Achieving market approval of a new peptide therapeutic requires phase-appropriate demonstration of product safety, efficacy and quality across all stages of development, including raw materials, drug substance and drug product manufacture, product di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b5e94d11d39f4fba6260c80b5526fe
https://doi.org/10.1039/9781788016445-00472
https://doi.org/10.1039/9781788016445-00472
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853(6):1416-1428
Proteins containing iron–sulfur (Fe–S) clusters arose early in evolution and are essential to life. Organisms have evolved machinery consisting of specialized proteins that operate together to assemble Fe–S clusters efficiently so as to minimiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2703e26478e866f4fc2b9a5a85aa895
Publikováno v:
Journal of Magnetic Resonance. 244:18-29
Spin relaxation in the rotating frame ( R 1 ρ ) is a powerful NMR technique for characterizing fast microsecond timescale exchange processes directed toward short-lived excited states in biomolecules. At the limit of fast exchange, only k ex = k 1 +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e2c9b42086b61c312092f98bc2211b
https://doi.org/10.1016/j.jmr.2014.04.010
https://doi.org/10.1016/j.jmr.2014.04.010