Zobrazeno 1 - 10
of 105
pro vyhledávání: '"James. H. Mcmahon"'
Autor:
David W. J. Griffin, Michael Dymock, Germaine Wong, C. Orla Morrissey, Sharon R. Lewin, Allen C. Cheng, Kirsten Howard, Julie A. Marsh, Kanta Subbarao, Michelle Hagenauer, Janine Roney, Anthony Cunningham, Tom Snelling, James H. McMahon
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Immunocompromised hosts (ICH) experience more breakthrough infections and worse clinical outcomes following infection with COVID-19 than immunocompetent people. Prophylactic monoclonal antibody therapies can be challenging to acce
Externí odkaz:
https://doaj.org/article/1be3382a6889486ca70a589275975189
Publikováno v:
HIV Research & Clinical Practice, Vol 25, Iss 1 (2024)
HIV community peer navigators and treatment officers are important sources of information and guidance for people living with HIV. We conducted an anonymous online survey with members of the treatment outreach network of the Australian National Assoc
Externí odkaz:
https://doaj.org/article/9a2c248fc9554d85abb7fa984e833312
Autor:
Matthew C. Pitman, Niamh Meagher, David J. Price, Ajantha Rhodes, J. Judy Chang, Barbara Scher, Brent Allan, Alan Street, James H. McMahon, Thomas A. Rasmussen, Paul U. Cameron, Jennifer F. Hoy, Stephen J. Kent, Sharon R. Lewin
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 3, Pp 100345- (2023)
Introduction: Antiretroviral therapy for people living with HIV-1 must be taken lifelong due to the persistence of latent virus in long-lived and proliferating CD4+ T cells. Vitamin D3 is a steroidal gene transcription regulator which exerts diverse
Externí odkaz:
https://doaj.org/article/d855402a478d4c80a0f9d2f7a2dcf56a
Autor:
Shivani Bhatt, Mellissa Bryant, Helen Lau, Ban-Kiem Tee, Beng Eu, Jessica O’Bryan, Ian Woolley, Jeni Mitchell, Alan Street, Sheranne Dobinson, Nicholas Medland, Judy Lamb, Andrew Mahony, Adrian Tramontana, Lyn-Li Lim, Amanda Wade, Christine Roder, William Mitchell, Christopher Sherman, Fran Bramwell, Craig Aboltins, Siaw Hui Wong, Maxine Giourouki, Jennifer F Hoy, James H McMahon
Publikováno v:
AIDS Research and Therapy, Vol 19, Iss 1, Pp 1-7 (2022)
Abstract Background There are more than 7,800 people living with human immunodeficiency virus (HIV) in Victoria, Australia. Crucial in maximising the individual and population level benefits from antiretroviral therapy (ART) is understanding how to a
Externí odkaz:
https://doaj.org/article/b3193bc730a84cd091169bd3f1f33eb6
Autor:
Jennifer R. Habel, Brendon Y. Chua, Lukasz Kedzierski, Kevin J. Selva, Timon Damelang, Ebene R. Haycroft, Thi H.O. Nguyen, Hui-Fern Koay, Suellen Nicholson, Hayley A. McQuilten, Xiaoxiao Jia, Lilith F. Allen, Luca Hensen, Wuji Zhang, Carolien E. van de Sandt, Jessica A. Neil, Katherine Pragastis, Jillian S.Y. Lau, Jaycee Jumarang, E. Kaitlynn Allen, Fatima Amanant, Florian Krammer, Kathleen M. Wragg, Jennifer A. Juno, Adam K. Wheatley, Hyon-Xhi Tan, Gabrielle Pell, Susan Walker, Jennifer Audsley, Arnold Reynaldi, Irani Thevarajan, Justin T. Denholm, Kanta Subbarao, Miles P. Davenport, P. Mark Hogarth, Dale I. Godfrey, Allen C. Cheng, Steven Y.C. Tong, Katherine Bond, Deborah A. Williamson, James H. McMahon, Paul G. Thomas, Pia S. Pannaraj, Fiona James, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Amy W. Chung, Clare L. Whitehead, Stephen J. Kent, Martha Lappas, Louise C. Rowntree, Katherine Kedzierska
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Pregnancy poses a greater risk for severe COVID-19; however, underlying immunological changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined immune responses to SARS-CoV-2 in unvaccinated pregnant and nonpregnant women
Externí odkaz:
https://doaj.org/article/5baf2d86cad54efcaef6a7913823280a
Autor:
Chris Y. Chiu, Maya D. Schou, James H. McMahon, Steven G. Deeks, Rémi Fromentin, Nicolas Chomont, Michelle N. Wykes, Thomas A. Rasmussen, Sharon R. Lewin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn people with HIV (PWH) both off and on antiretroviral therapy (ART), the expression of immune checkpoint (IC) proteins is elevated on the surface of total and HIV-specific T-cells, indicating T-cell exhaustion. Soluble IC proteins and t
Externí odkaz:
https://doaj.org/article/64a3fccd9520467d87cf447a13d006fc
Autor:
Wuji Zhang, Brendon Y. Chua, Kevin J. Selva, Lukasz Kedzierski, Thomas M. Ashhurst, Ebene R. Haycroft, Suzanne K. Shoffner-Beck, Luca Hensen, David F. Boyd, Fiona James, Effie Mouhtouris, Jason C. Kwong, Kyra Y. L. Chua, George Drewett, Ana Copaescu, Julie E. Dobson, Louise C. Rowntree, Jennifer R. Habel, Lilith F. Allen, Hui-Fern Koay, Jessica A. Neil, Matthew J. Gartner, Christina Y. Lee, Patiyan Andersson, Sadid F. Khan, Luke Blakeway, Jessica Wisniewski, James H. McMahon, Erica E. Vine, Anthony L. Cunningham, Jennifer Audsley, Irani Thevarajan, Torsten Seemann, Norelle L. Sherry, Fatima Amanat, Florian Krammer, Sarah L. Londrigan, Linda M. Wakim, Nicholas J. C. King, Dale I. Godfrey, Laura K. Mackay, Paul G. Thomas, Suellen Nicholson, Kelly B. Arnold, Amy W. Chung, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The immune response to SARS-CoV-2 infection is variable but has been linked to prognosis and the development of severe immunopathology. Here the authors assess a range of immune parameters in both peripheral blood and respiratory samples, providing a
Externí odkaz:
https://doaj.org/article/3dbf74c705f948919beba2c6dc7dada4
Autor:
James H. McMahon, Jillian S.Y. Lau, Anna Coldham, Janine Roney, Michelle Hagenauer, Sally Price, Mellissa Bryant, Jill Garlick, Anne Paterson, Sue J. Lee, Jess O'Bryan, Anna Hearps, Gilda Tachedjian, Henry Pinskier, Cameron Phillips, Stuart Garrow, Nathan Pinskier, Robert Melvin, Luke Blakeway, Jessica A. Wisniewski, Sally Byers, Gnei Z. Badoordeen, Stephanie Pereira, Katherine Pragastis, Jason A. Trubiano, Kyra Y.L. Chua, Marion Kainer, James S. Molton, Bradley J. Gardiner, Anna B. Pierce, Allen Cheng, Benjamin A. Rogers, Anton Y. Peleg
Publikováno v:
EClinicalMedicine, Vol 54, Iss , Pp 101703- (2022)
Summary: Background: Well tolerated antivirals administered early in the course of COVID-19 infection when the viremia is highest could prevent progression to severe disease. Favipiravir inhibits SARS-CoV-2 viral replication in vitro with evidence of
Externí odkaz:
https://doaj.org/article/21ec5c21efe3489bb10bb9f88cc2c246
Autor:
Jillian S. Y. Lau, Miranda Z. Smith, Brent Allan, Cipriano Martinez, Jennifer Power, Sharon R. Lewin, James H. McMahon
Publikováno v:
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-6 (2020)
Abstract Background Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving antiretroviral therapy (ART)-free HIV remission. Understanding the acceptability of ATI amongst
Externí odkaz:
https://doaj.org/article/31dd3701851a46f389b62318372dd2a9
Autor:
James H. McMahon, Jillian S. Y. Lau, Janine Roney, Benjamin A. Rogers, Jason Trubiano, Joseph Sasadeusz, James S. Molton, Bradley Gardiner, Sue J. Lee, Jennifer F. Hoy, Allen Cheng, Anton Y. Peleg
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Abstract Objectives Primary objective: To determine the efficacy of a candidate antiviral on time to virological cure compared to standard of care within 14 days of randomisation Secondary objectives: • To determine the safety of the antiviral •
Externí odkaz:
https://doaj.org/article/efa0dd56e549437b9005d47bfa1d1508