Zobrazeno 1 - 10
of 26
pro vyhledávání: '"James langridge"'
Autor:
Mariateresa Maldini, Fausta Natella, Simona Baima, Giorgio Morelli, Cristina Scaccini, James Langridge, Giuseppe Astarita
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 13678-13691 (2015)
The consumption of vegetables belonging to the family Brassicaceae (e.g., broccoli and cauliflower) is linked to a reduced incidence of cancer and cardiovascular diseases. The molecular composition of such plants is strongly affected by growing condi
Externí odkaz:
https://doaj.org/article/161e2bdf439a4691afa9f42affd88a9a
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 8, Pp 1772-1783 (2014)
An ultraperformance LC (UPLC) method for the separation of different lipid molecular species and lipid isomers using a stationary phase incorporating charged surface hybrid (CSH) technology is described. The resulting enhanced separation possibilitie
Externí odkaz:
https://doaj.org/article/31683a1a2a814abdb8e01880b42fbeb0
Autor:
Paul J S Skipp, Chris Hughes, Thérèse McKenna, Richard Edwards, James Langridge, Nicholas R Thomson, Ian N Clarke
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149011 (2016)
The obligate intracellular developmental cycle of Chlamydia trachomatis presents significant challenges in defining its proteome. In this study we have applied quantitative proteomics to both the intracellular reticulate body (RB) and the extracellul
Externí odkaz:
https://doaj.org/article/90a1d0c1527b4141aea276c2bbc11ce2
Autor:
Tanya C Burch, Giorgis Isaac, Christiana L Booher, Johng S Rhim, Paul Rainville, James Langridge, Andrew Baker, Julius O Nyalwidhe
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134206 (2015)
Prostate cancer (PCa) is the most prevalent cancer amongst men and the second most common cause of cancer related-deaths in the USA. Prostate cancer is a heterogeneous disease ranging from indolent asymptomatic cases to very aggressive life threateni
Externí odkaz:
https://doaj.org/article/f8e179c8184b426bb988cefb0d25f9b5
Autor:
Giuseppe Astarita, Jennifer H McKenzie, Bin Wang, Katrin Strassburg, Angela Doneanu, Jay Johnson, Andrew Baker, Thomas Hankemeier, James Murphy, Rob J Vreeken, James Langridge, Jing X Kang
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96221 (2014)
A balanced omega-6/omega-3 polyunsaturated fatty acid (PUFA) ratio has been linked to health benefits and the prevention of many chronic diseases. Current dietary intervention studies with different sources of omega-3 fatty acids (omega-3) lack appro
Externí odkaz:
https://doaj.org/article/9816b672132b4ef1a7ee788d32022121
Autor:
Lieke Lamont, Darya Hadavi, Andrew P. Bowman, Bryn Flinders, Dale Cooper‐Shepherd, Martin Palmer, Jan Jordens, Ynze Mengerink, Maarten Honing, James Langridge, Tiffany Porta Siegel, Rob J. Vreeken, Ron M. A. Heeren
Publikováno v:
Rapid Communications in Mass Spectrometry, 37(5):e9439. Wiley
RATIONALE: Isomeric separation of prostanoids is often a challenge and requires chromatography and time-consuming sample preparation. Multiple prostanoid isomers have distinct in vivo functions crucial to understand the inflammation process, includin
Autor:
Emrys A. Jones, Dipa Gurung, Fiona Henderson, Matthew Gentry, Danielle McDougall, Yasmin Shanneik, James Langridge, Adam McMahon, Zoltan Takats
Publikováno v:
Cancer Research. 79:4534-4534
Mass spectrometry imaging allows for the presence and abundance of a wide range of bio-molecules to be measured directly from tissue sections without the use of labels or tags. This results in the ability to compare the spatial distribution of hundre
Autor:
John Rontree, Michael Przybylski, Christiaan Karreman, Karin M Danzer, Stefan Schildknecht, Nick Tomczyk, Michael L. Gross, Marcel Leist, James Langridge, Camelia Vlad, Thomas Ciossek, Bastian Hengerer, Kathrin Lindner, Alina Petre
Publikováno v:
ChemBioChem. 12:2740-2744
Gas-phase protein separation by ion mobility: With its ability to separate the Parkinson's disease protein Alpha-synuclein and its autoproteolytic products—despite the small concentrations of the latter—ion-mobility MS has enabled the characteriz
Autor:
Rosamonde E. Banks, James Langridge, T. McKenna, David A Cairns, Niroshini Nirmalan, C. Hughes, Peter Selby, Jianhe Peng, Patricia Harnden
Publikováno v:
Journal of Proteome Research
Annotated formalin-fixed, paraffin-embedded (FFPE) tissue archives constitute a valuable resource for retrospective biomarker discovery. However, proteomic exploration of archival tissue is impeded by extensive formalin-induced covalent cross-linking
Autor:
James Langridge, Sandrine Da Cruz, Francis Vilbois, Phillipe A. Parone, Ioannis Xenarios, Jean-Claude Martinou
Publikováno v:
Journal of Biological Chemistry. 278:41566-41571
Mitochondria play a crucial role in cellular homeostasis, which justifies the increasing interest in mapping the different components of these organelles. Here we have focused our study on the identification of proteins of the mitochondrial inner mem