Whole-body autoradiography reveals that the Peptostreptococcus magnus immunoglobulin-binding domains of protein L preferentially target B lymphocytes in the spleen and lymph nodes in vivo

Autor: Lars Björck, Ulf Yrlid, James de Jersey, David Smith, Roland D'Argy, Mats Nilsson, Mary Jo Wick

Publikováno v: Cellular Microbiology. 6:609-623

Protein L is an immunoglobulin (Ig)-binding protein produced by the Gram-positive bacterium Peptostreptococcus magnus that interacts with the variable region of Ig kappa light chains. The Ig light chain-binding capacity of protein L gives it the pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44bfa601677d3dfccf5a2674fed2d646
https://doi.org/10.1111/j.1462-5822.2004.00386.x

Reviewers

Autor: Gordon Ada, Elaine Alexander, Mark Anderson, Robert Anderson, Grant Anhalt, Jacques Banchereau, Alan Baxter, Richard Boyd, Ware Branch, Robert Brodsky, James Bussel, Stanley Cohen, Antonio Coutinho, Terry Davies, James De Jersey, Barbara Detrick, Daniel Drachman, Marc Feldmann, Dori Germolec, James Goding, Michael Good, Malcolm Greaves, Peter Gregersen, Andrew Grigg, Mark Hedger, Phil Hodgkin, Mark Hogarth, Peter Hollingsworth, Derek Jewell, David Jones, Thomas Kay, Vijay Kuchroo, Michael Lenardo, Peter Lipsky, Mark Mamula, Geoffrey McCaughan, Hugh McDevitt, Ruslan Medzhitov, Stephen Miller, Grant Morahan, Kamal D. Moudgil, Robert Nakamura, Dolores Njoku, Abner Notkins, Klaus Rajewski, Westley Reeves, Morris Reichlin, Peter Roberts-Thomson, Ethan Shevach, Ken Shortman, Lawrence Steinman, Cory Teuscher, Argyrios Theophilopoulos, Tony Tiganis, John Todd, Ban-Hock Toh, George Tsokos, John Vierling, Gabriel Virella, Raivo Uibo, Emil Unanue, Clive Wasserfall, Senga Whittingham, Ian Wicks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7d134a06b6717bfce4614d0ffd629f3
https://doi.org/10.1016/b978-012595961-2/50001-9

Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity

Autor: James de Jersey, Danielle Carmignac, Brigitta Stockinger, Iain C. A. F. Robinson, Thomas Barthlott, Paul Le Tissier

Publikováno v: Immunology. 111(3)

We have previously shown, in a transgenic mouse model, that the pituitary gland is susceptible to CD8 T-cell-mediated autoimmunity, triggered by a cell-specific model autoantigen, resulting in pan-anterior pituitary hypophysitis and dwarfism. In the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0464d0af41a6cd34c9ecbc6ec83fd3be
https://pubmed.ncbi.nlm.nih.gov/15009425

Activation of CD8 T cells by antigen expressed in the pituitary gland

Autor: James de Jersey, Iain C. A. F. Robinson, Danielle Carmignac, Brigitta Stockinger, Thomas Barthlott

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 169(12)

Ag expressed exclusively in the anterior pituitary gland and secreted locally by pituitary somatotrophs can gain access to the MHC class I presentation pathway and activate CD8 T cells. Influenza nucleoprotein (NP) was expressed as a transgene under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa4581afea952906d65440978f4469d
https://pubmed.ncbi.nlm.nih.gov/12471106