Zobrazeno 1 - 10
of 81
pro vyhledávání: '"James and Sun"'
Publikováno v:
The British Journal of Psychiatry. 222:191-195
SummaryAntiseizure medications (ASMs) are the second most widely prescribed psychotropic for people with intellectual disabilities in England. Multiple psychotropic prescribing is prevalent in almost half of people with intellectual disabilities on A
Publikováno v:
British Journal of Clinical Pharmacology.
Autor:
James J. Sun, Lance Watkins, William Henley, Richard Laugharne, Heather Angus-Leppan, Indermeet Sawhney, Meissam Moghaddassian Shahidi, Kiran Purandare, Mogbeyiteren Eyeoyibo, Mark Scheepers, Geraldine Lines, Robert Winterhalder, Bhathika Perera, Benjamin Hyams, Samantha Ashby, Rohit Shankar
Publikováno v:
Journal of Neurology.
Autor:
Elizabeth M. Swisher, Iain A. McNeish, Thomas C. Harding, James D. Brenton, Heidi Giordano, James X. Sun, Robert L. Coleman, Gottfried E. Konecny, Clare L. Scott, Scott H. Kaufmann, Setsuko K. Chambers, David M. O'Malley, Lara Maloney, Jeffrey D. Isaacson, Elaina Mann, Lan-Thanh Vo, Carmen Say, Marc R. Radke, Elena Helman, Anna V. Tinker, Isabelle Ray-Coquard, Ana Oaknin, Amit M. Oza, Maria I. Harrell, Kevin K. Lin
Table S1 is an Excel sheet that provides a detailed listing of primary BRCA and TP53 mutations as well as BRCA reversion mutations detected in pretreatment and postprogression circulating cell-free DNA and tumor biopsy samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0f0f04c6ffd5876ef9cd4816ed5860
https://doi.org/10.1158/2159-8290.22532690
https://doi.org/10.1158/2159-8290.22532690
Autor:
Christine M. Lovly, Jeffrey A. Sosman, Ryan J. Sullivan, Philip J. Stephens, Vincent A. Miller, Yu Shyr, Harlan Robins, Catherine Sanders, Jeffrey S. Ross, Justin M. Cates, Justin M. Balko, Igor Puzanov, Dennie T. Frederick, Yuting He, James X. Sun, Sohail Balasubramanian, Siraj M. Ali, Joel Greenbowe, Zachary R. Chalmers, David Fabrizio, Riley C. Ennis, Xingyi Guo, Yaomin Xu, Erik Yusko, Matthew J. Rioth, Garrett M. Frampton, Douglas B. Johnson
Therapeutic antibodies blocking programmed death-1 and its ligand (PD-1/PD-L1) induce durable responses in a substantial fraction of melanoma patients. We sought to determine whether the number and/or type of mutations identified using a next-generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15363619a8ba34271f174c2683420406
https://doi.org/10.1158/2326-6066.c.6548372.v1
https://doi.org/10.1158/2326-6066.c.6548372.v1
Autor:
Christine M. Lovly, Jeffrey A. Sosman, Ryan J. Sullivan, Philip J. Stephens, Vincent A. Miller, Yu Shyr, Harlan Robins, Catherine Sanders, Jeffrey S. Ross, Justin M. Cates, Justin M. Balko, Igor Puzanov, Dennie T. Frederick, Yuting He, James X. Sun, Sohail Balasubramanian, Siraj M. Ali, Joel Greenbowe, Zachary R. Chalmers, David Fabrizio, Riley C. Ennis, Xingyi Guo, Yaomin Xu, Erik Yusko, Matthew J. Rioth, Garrett M. Frampton, Douglas B. Johnson
Supplementary Table 1: Results for samples obtained (less than or equal to) 12 months prior to therapy (optimal) vs. those obtained >12 months from treatment or shortly after starting therapy (non-optimal). Supplementary Table 2: Cox proportional haz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938003187c5e8f00cf881b1a4f681805
https://doi.org/10.1158/2326-6066.22537262
https://doi.org/10.1158/2326-6066.22537262
Autor:
Elizabeth M. Swisher, Iain A. McNeish, Thomas C. Harding, James D. Brenton, Heidi Giordano, James X. Sun, Robert L. Coleman, Gottfried E. Konecny, Clare L. Scott, Scott H. Kaufmann, Setsuko K. Chambers, David M. O'Malley, Lara Maloney, Jeffrey D. Isaacson, Elaina Mann, Lan-Thanh Vo, Carmen Say, Marc R. Radke, Elena Helman, Anna V. Tinker, Isabelle Ray-Coquard, Ana Oaknin, Amit M. Oza, Maria I. Harrell, Kevin K. Lin
A key resistance mechanism to platinum-based chemotherapies and PARP inhibitors in BRCA-mutant cancers is the acquisition of BRCA reversion mutations that restore protein function. To estimate the prevalence of BRCA reversion mutations in high-grade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c393b81f60afdff6fe8e9b164e1dfd80
https://doi.org/10.1158/2159-8290.c.6546800.v1
https://doi.org/10.1158/2159-8290.c.6546800.v1
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Long tail distribution of the top 50 altered genes in pediatric sarcoma (S1); Long tail distribution of the top 50 altered genes in pediatric extracranial embryonal tumors (S2); Long tail distribution of the top 50 altered genes in pediatric brain tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1787586c646efaf2a677928246eca2
https://doi.org/10.1158/0008-5472.22414374
https://doi.org/10.1158/0008-5472.22414374
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Gene lists for Version 1 of the FoundationOne Assay (S1); Gene lists for Version 2 of the FoundationOne Assay (S2); Gene lists for Version 3 of the FoundationOne Assay (S3); Gene lists for Version 4 of the FoundationOne Assay (S4); Gene lists for Ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d519b7259eab3f249fe92b2affbb4a8
https://doi.org/10.1158/0008-5472.22414371.v1
https://doi.org/10.1158/0008-5472.22414371.v1
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Pediatric cancers are generally characterized by low mutational burden and few recurrently mutated genes. Recent studies suggest that genomic alterations may help guide treatment decisions and clinical trial selection. Here, we describe genomic profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da4fd89d6550e13c627bd12d2463218
https://doi.org/10.1158/0008-5472.c.6508959.v1
https://doi.org/10.1158/0008-5472.c.6508959.v1