Zobrazeno 1 - 10
of 13
pro vyhledávání: '"James Zondlo"'
Autor:
Isabelle Dussault, Josette Carnahan, Ted Judd, Ralf Schwandner, John McCarter, John Robinson, Miguel Tisha San, Cherylene A. Plewa, Aaron R. Ellison, Yu Sun, James Zondlo, Angela Jackson, Flordeliza Fajardo, Vivienne J. Watson, Astrid A. Ruefli-Brasse, Paul D. Kassner, Kim Quon, Manory Fernando, Amro Shehabeldin, Anke Munzli, Robert J. Kurzeja, Yihong Zhang, Carol Babij
PDF file - 159K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757e70de53080fffbb1af5da72dff499
https://doi.org/10.1158/0008-5472.22389273
https://doi.org/10.1158/0008-5472.22389273
Autor:
Isabelle Dussault, Josette Carnahan, Ted Judd, Ralf Schwandner, John McCarter, John Robinson, Miguel Tisha San, Cherylene A. Plewa, Aaron R. Ellison, Yu Sun, James Zondlo, Angela Jackson, Flordeliza Fajardo, Vivienne J. Watson, Astrid A. Ruefli-Brasse, Paul D. Kassner, Kim Quon, Manory Fernando, Amro Shehabeldin, Anke Munzli, Robert J. Kurzeja, Yihong Zhang, Carol Babij
XLS file 3927K, STK33 enzymatic activity and cellular activities for molecules a-l from Figure 6E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b47ec227279b36dd082f73958f4d0d
https://doi.org/10.1158/0008-5472.22389258
https://doi.org/10.1158/0008-5472.22389258
Autor:
Isabelle Dussault, Josette Carnahan, Ted Judd, Ralf Schwandner, John McCarter, John Robinson, Miguel Tisha San, Cherylene A. Plewa, Aaron R. Ellison, Yu Sun, James Zondlo, Angela Jackson, Flordeliza Fajardo, Vivienne J. Watson, Astrid A. Ruefli-Brasse, Paul D. Kassner, Kim Quon, Manory Fernando, Amro Shehabeldin, Anke Munzli, Robert J. Kurzeja, Yihong Zhang, Carol Babij
PDF file - 7714K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178e8e963075513ef199a9cf1e50e5a0
https://doi.org/10.1158/0008-5472.22389267
https://doi.org/10.1158/0008-5472.22389267
Autor:
Isabelle Dussault, Josette Carnahan, Ted Judd, Ralf Schwandner, John McCarter, John Robinson, Miguel Tisha San, Cherylene A. Plewa, Aaron R. Ellison, Yu Sun, James Zondlo, Angela Jackson, Flordeliza Fajardo, Vivienne J. Watson, Astrid A. Ruefli-Brasse, Paul D. Kassner, Kim Quon, Manory Fernando, Amro Shehabeldin, Anke Munzli, Robert J. Kurzeja, Yihong Zhang, Carol Babij
XLS file - 175K, Effects of 515 small molecules on STK33 enzymatic activity vs. phosphorylation of RPS6 in cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aacee7c5590b31050017f16f182de07
https://doi.org/10.1158/0008-5472.22389264
https://doi.org/10.1158/0008-5472.22389264
Autor:
Isabelle Dussault, Josette Carnahan, Ted Judd, Ralf Schwandner, John McCarter, John Robinson, Miguel Tisha San, Cherylene A. Plewa, Aaron R. Ellison, Yu Sun, James Zondlo, Angela Jackson, Flordeliza Fajardo, Vivienne J. Watson, Astrid A. Ruefli-Brasse, Paul D. Kassner, Kim Quon, Manory Fernando, Amro Shehabeldin, Anke Munzli, Robert J. Kurzeja, Yihong Zhang, Carol Babij
PDF file - 119K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912002ea258ee186336f270303a0986b
https://doi.org/10.1158/0008-5472.22389270.v1
https://doi.org/10.1158/0008-5472.22389270.v1
Autor:
Vivian S. W. Li, Emily Flashman, Robert J.M. Kurzeja, Steven R. Jordan, Christopher J. Schofield, Jeffrey Lewis, Kirsty S. Hewitson, Michael A. McDonough, Benoît M. R. Liénard, Neil J. Oldham, James Zondlo, Rashid Syed, Luke A. McNeill, Christopher Mohr, Rasheduzzaman Chowdhury, Evelyn Yang, Ian J. Clifton
Cellular and physiological responses to changes in dioxygen levels in metazoans are mediated via the posttranslational oxidation of hypoxia-inducible transcription factor (HIF). Hydroxylation of conserved prolyl residues in the HIF-α subunit, cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc6181ba5e68ed20b0a0ec7964076d6
https://ora.ox.ac.uk/objects/uuid:ed881d80-0faa-4548-8fe0-c508704fb767
https://ora.ox.ac.uk/objects/uuid:ed881d80-0faa-4548-8fe0-c508704fb767
Autor:
Minghan Wang, James Busby, James Zondlo, Chester Chenguang Yuan, Stephen W. Young, Shou-Hua Xiao, Ki Won Kim, Mei-Chu Lo, Harvey Yamane
Publikováno v:
Analytical Biochemistry. 376:122-130
Malonyl-CoA decarboxylase (MCD) catalyzes the conversion of malonyl-CoA to acetyl-CoA and thereby regulates malonyl-CoA levels in cells. Malonyl-CoA is a potent inhibitor of mitochondrial carnitine palmitoyltransferase-1, a key enzyme involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5e7f59a0a1874252b5529c2952d521
https://doi.org/10.1016/j.ab.2008.01.033
https://doi.org/10.1016/j.ab.2008.01.033
Publikováno v:
Protein Expression and Purification. 53:16-23
The full-length human acetyl-CoA carboxylase 1 (ACC1) was expressed and purified to homogeneity by two separate groups (Y.G. Gu, M. Weitzberg, R.F. Clark, X. Xu, Q. Li, T. Zhang, T.M. Hansen, G. Liu, Z. Xin, X. Wang, T. McNally, H. Camp, B.A. Beutel,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b18a063f6079858841ddd3e9eb89933
https://doi.org/10.1016/j.pep.2006.11.021
https://doi.org/10.1016/j.pep.2006.11.021
Autor:
Christopher M. Tegley, Robert J.M. Kurzeja, Rashid Syed, Vivian S. W. Li, Leszek Poppe, Jeffrey Lewis, James Zondlo, Evelyn Yang
Publikováno v:
Journal of the American Chemical Society. 131(46)
In aqueous solution, azaquinolone inhibitors bind to prolyl 4-hydroxylase in two different orientations, as first detected by (19)F spectroscopy. This contrasts with the crystallographic structure where only one orientation has been determined. Disse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e082d500129361e04db1c0ff7d230d9c
https://pubmed.ncbi.nlm.nih.gov/19886658
https://pubmed.ncbi.nlm.nih.gov/19886658
Autor:
Christopher Mohr, Leszek Poppe, Opas Nuanmanee, Christopher M. Tegley, Timothy S. Harvey, James Zondlo, Janet Cheetham
Publikováno v:
Journal of biomolecular screening. 12(3)
A comprehensive approach to target screening, hit validation, and binding site determination by nuclear magnetic resonance (NMR) spectroscopy is presented. NMR (19)F signal perturbation was used to screen a small compound library and identify candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8073afe3873dca17eb4eb976fc5cdb88
https://pubmed.ncbi.nlm.nih.gov/17438066
https://pubmed.ncbi.nlm.nih.gov/17438066