Zobrazeno 1 - 3
of 3
pro vyhledávání: '"James Z. Curlin"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunocompetent and immunocompromised murine models have been instrumental in answering important questions regarding ZIKV pathogenesis and vertical transmission. However, mimicking human congenital zika syndrome (CZS) characteristics in
Externí odkaz:
https://doaj.org/article/f9f69ba0581a465ca9aa12114d2af2b0
Autor:
James Z. Curlin, Kimberly Schmitt, Leila Remling-Mulder, Ryan V. Moriarty, John J. Baczenas, Kelly Goff, Shelby O'Connor, Mark Stenglein, Preston A. Marx, Ramesh Akkina
Publikováno v:
Frontiers in Virology, Vol 1 (2021)
Simian immunodeficiency virus native to sooty mangabeys (SIVsm) is believed to have given rise to HIV-2 through cross-species transmission and evolution in the human. SIVmac239 and SIVB670, pathogenic to macaques, and SIVhu, isolated from an accident
Externí odkaz:
https://doaj.org/article/d97621aa07f743bab0ffc72464e7ee60
Autor:
James Z. Curlin, Kimberly Schmitt, Leila Remling‐Mulder, Jared Morrison, John J. Baczenas, Corina Valencia Tibbits, Kelly Goff, Shelby O'Connor, Mark Stenglein, Preston Marx, Ramesh Akkina
Publikováno v:
Journal of Medical Primatology. 51:284-287
Serial passage of SIVmac239 allows for greater understanding of the genetic changes necessary for cross-species transmission of primate lentiviruses into humans. Using humanized mice, we show that adaptive mutations continue to accumulate in SIVmac23