Abstract 6606: Biomarker discovery in non-small-cell lung cancer enabled by deep multi-omics profiling of proteins, metabolites, transcripts, and genes in blood

Autor: Jinlyung Choi, Ajinkya Kokate, Ehdieh Khaledian, Manway Liu, Preethi Prasad, John Blume, Jessica Chan, Rea Cuaresma, Kevin Dai, Manoj Khadka, Thidar Khin, Yuya Kodama, Joon-Yong Lee, Hoda Malekpour, Megan Mora, Nithya Mudaliar, Sara Nouri Golmaei, Madhuvanthi Ramaiah, Saividya Ramaswamy, Peter Spiro, Dijana Vitko, Kavya Swaminathan, James Yee, Brian Young, Chinmay Belthangady, Bruce Wilcox, Brian Koh, Philip Ma

Publikováno v: Cancer Research. 83:6606-6606

Lung cancer is the leading cause of cancer-related deaths in the United States, with estimates of 236,740 new cases and 118,830 deaths in 2022 secondary to the disease. Blood-based liquid biopsies hold promise to reduce morbidity and mortality from l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::220f4bd520b98cf50f8ece09ae233269
https://doi.org/10.1158/1538-7445.am2023-6606

Abstract A038: High-dimensional, multi-omics analyses of proteins, metabolites, transcripts, and genes enable biomarker discovery in early- and late-stage pancreatic cancer

Autor: Ehdieh Khaledian, Preethi Prasad, John Blume, Ghristine Bundalian, Connie Chao-Shern, Jinlyung Choi, Rea Cuaresma, Jared Deyarmin, Jun Heok Jang, Manoj Khadka, Thidar Khin, Yuya Kodama, Ajinkya Kokate, Joon-Yong Lee, Manway Liu, Nithya Mudaliar, Madhuvanthi Ramaiah, Saividya Ramaswamy, Peter Spiro, Kavya Swaminathan, Preston Williams, Mi Yang, James Yee, Brian Young, Robert Zawada, Susan Zhang, Chinmay Belthangady, Bruce Wilcox, Philip Ma

Publikováno v: Cancer Research. 82:A038-A038

Pancreatic cancer is the third leading cause of cancer-related deaths in the United States. Disease biomarkers quantified from blood-based assays may help reduce mortality by enabling early detection, treatment selection, or response and resistance a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f3f28083eff9a445a099272caf4f3c9
https://doi.org/10.1158/1538-7445.panca22-a038

Contributors

Autor: Michael J. Ackerman, Minhaz Uddin Ahmed, Sun Hee Ahn, R. Rand Allingham, Jude Alsarraj, Matthew L. Anderson, Brian H. Annex, Christina K. Augustine, Sergio E. Baranzini, Peter J. Barnes, Georgia M. Beasley, Richard C. Becker, Ivor J. Benjamin, D. Woodrow Benson, Jacob Fog Bentzon, Philip S. Bernard, Lars Bertram, Laura M. Beskow, Brigitta Bondy, J. Martijn Bos, Gabriella L. Boulting, Jerome S. Brody, April S. Brown, Kenneth H. Buetow, Lars Bullinger, Atul J. Butte, David J. Carey, George Carlson, David Chen, Maria Chahrour, E. Antonio Chiocca, Alex H. Cho, Carolyn Compton, Robert Cook-Deegan, Nicholas Craddock, Michael Coulter, Samir B. Damani, Jacqueline S. Danik, Sandeep Dave, Russell Dedrick, Frank R. DeLeo, Eleftherios P. Diamandis, Ayotunde O. Dokun, Gregory J. Downing, Stephen L. Eck, Lucas B. Edelman, Kevin C. Eggan, Erling Falk, Hawazin Faruki, Junjie Feng, Eleanora Anna Margaretha Festen, Jose C. Florez, Vance G. Fowler, Jennifer A. Freedman, Hudson H. Freeze, Stefan Fröhling, David J. Galas, Glenn S. Gerhard, Daniel H. Geschwind, Ad Geurts van Kessel, Robert B. Giffin, Geoffrey S. Ginsburg, Megan Goodall, Praveen Govender, Robert C. Green, Chris Gunter, Marta Gwinn, Susanne B. Haga, James R. Heath, Robert A. Hegele, John Holton, Leroy Hood, Kent W. Hunter, Daehee Hwang, Gail Javitt, Gina Jefferson, Sam John, Keith J. Johnson, Toby Johnson, Tisha R. Joy, Sekar Kathiresan, Hasmeena Kathuria, Arabindra B. Katwal, Kensaku Kawamoto, Andrea Kelly, Muin J. Khoury, Jin Woo Kim, Stephen F. Kingsmore, Tod Klingler, Scott D. Kobayashi, Isaac S. Kohane, Virginia Byers Kraus, Roland P. Kuiper, Myla Lai-Goldman, Neil E. Lamb, Sevdalina Nikolova Lambova, Matthew B. Lanktree, Sean E. Lawler, David H. Ledbetter, Charles Lee, Inyoul Lee, Karine G. Le Roch, Samuel Levy, Sophie Limou, Wennuan Liu, Yutao Liu, Barry London, Jeffrey P. MacKeigan, Elaine R. Mardis, Hector Marquez, Marco Marra, Christa Lese Martin, Lisa J. Martin, Steven A. McCarroll, John McHutchison, Howard L. McLeod, Asunción Mejías, Eric B. Meltzer, M. Anthony Moody, Ryan D. Morin, M. Arthur Moseley, Joanna L. Mountain, Ulf Müller-Ladner, Patricia B. Munroe, Bobby G. Ng, Paul W. Noble, Michael C. O’Donovan, Kunle Odunsi, Gilbert S. Omenn, Steve R. Ommen, Lori A. Orlando, Albert D.M.E. Osterhaus, Michael J. Owen, Neelroop N. Parikshak, Keyur Patel, Maria P. Pavlou, Nina P. Paynter, Tanja Pejovic, Michael X. Pham, Robert M. Plenge, Mihai V. Podgoreanu, Nadia Ponts, Nathan D. Price, Bruce Quinn, Francisco J. Quintana, Daniel J. Rader, Octavio Ramilo, Heidi L. Rehm, Benjamin Rhodes, Paul M. Ridker, Erin Rooney Riggs, Jeffrey S. Ross, Wendy S. Rubinstein, Carol J. Saunders, Joan Scott, Nicholas A. Shackel, Svati H. Shah, Richard Simon, Sanjay M. Sisodiya, Saskia L. Smits, John A. Stamatoyannopoulos, Glenn D. Steele, Mark P. Steele, Tessandra Stewart, Giovana R. Thomas, Eric J. Topol, Sean R. Tunis, Aubrey R. Turner, Douglas S. Tyler, David L. Veenstra, Ramprasath Venkatachalam, Deepak Voora, Timothy J. Vyse, Christopher A. Walsh, Katherine Walsh, Hao Wang, Jun Wang, Rinse K. Weersma, Howard L. Weiner, Scott T. Weiss, C. William Wester, David N. Wholley, Janey L. Wiggs, Cisca Wijmenga, Huntington F. Willard, Hywel J. Williams, Marc S. Williams, Cheryl A. Winkler, Janet Woodcock, Christopher W. Woods, Pae C. Wu, Jianfeng Xu, James Yee, Hyuntae Yoo, Timothy Yu, Jing Zhang, Yurong Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::911ba1338a881749b191a76ebd82c89a
https://doi.org/10.1016/b978-0-12-382227-7.00124-5

Indomethacin Inhibition of Middle Ear Bone Resorption

Autor: Kristi Adachi, James Yee, Richard A. Chole

Publikováno v: Archives of Otolaryngology - Head and Neck Surgery. 117:267-269

Localized osteoclastic bone resorption is responsible for the pathological changes within the middle and inner ear, which result in hearing loss and vertigo in chronic otitis media and otosclerosis. The local control of osteoclastic bone resorption i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f3e98511b797114321b28da3ba38da
https://doi.org/10.1001/archotol.1991.01870150035002

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