Zobrazeno 1 - 2
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pro vyhledávání: '"James Y. Mamone"'
Autor:
M B S Laura Bohn, Mariana M. Belcheva, Anantha N. Manepalli, Gail E. Thomas, Frank E. Johnson, Eric C. Pan, Carmine J. Coscia, James Y. Mamone
Publikováno v:
Cancer. 83:2561-2566
BACKGROUND Opioid agonists can inhibit cell proliferation in various neural tumor cell lines, including rat gliomas. Because opioid antimitogenic effects are mediated by opioid receptors, it was of interest to the authors to determine opioid receptor
Autor:
Frank E. Johnson, Michael D. Rush, Gail E. Thomas, James Y. Mamone, Maria Szücs, Carmine J. Coscia, Wojciech T. Bem
Publikováno v:
Life Sciences. 46:1279-1286
Human brain tumors (obtained as surgical specimens) and nude mouse-borne human neuroblastomas and gliomas were analyzed for sigma and opioid receptor content. Sigma binding was assessed using [3H]1,3-di-o-tolylguanidine (DTG), whereas opoid receptor