Zobrazeno 1 - 10
of 14
pro vyhledávání: '"James Y. Fukunaga"'
Publikováno v:
Journal of Medicinal Chemistry. 21:1327-1330
The synthesis and antiallergic activity of a new series of 9H-xanthen-9-one-2-carboxylic acids are described. Antiallergic activity was evaluated in the rat passive cutaneous anaphylaxis (PCA) screen. Biological results were analyzed using regression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6370d01045a60b12f32133c327fa16
https://doi.org/10.1021/jm00210a034
https://doi.org/10.1021/jm00210a034
Autor:
James Y. Fukunaga, Clay M. Sharts, Gordon M. Cohen, Richard A. Minns, Klaus Hummel, Steven P. Elliott, Paul D. Bartlett
Publikováno v:
Journal of the American Chemical Society. 94:2899-2902
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::251c2b1a5923b087ae9fb4fcd8cd6d85
https://doi.org/10.1021/ja00763a081
https://doi.org/10.1021/ja00763a081
Autor:
James Y. Fukunaga, Robert W. Taft
Publikováno v:
Journal of the American Chemical Society. 97:1612-1614
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab21ef85e4d2ba408bbc1ade38c618b
https://doi.org/10.1021/ja00839a076
https://doi.org/10.1021/ja00839a076
Publikováno v:
Journal of medicinal chemistry. 24(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5f8bb0ebf1523cdb241908a046ee7b
https://pubmed.ncbi.nlm.nih.gov/7241512
https://pubmed.ncbi.nlm.nih.gov/7241512
Autor:
James Y. Fukunaga, John G. Topliss
Publisher Summary Applications of quantitative structure–activity relationships (QSAR) approaches have been quite numerous in different fields, such as the central nervous system (CNS), cardiovascular, hormone, etc. A number of applications of QSAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7764e7748a515ce64decf533c16ee705
https://doi.org/10.1016/s0065-7743(08)60633-8
https://doi.org/10.1016/s0065-7743(08)60633-8
Publikováno v:
Chemischer Informationsdienst. 10
The synthesis and antiallergic activity of a new series of 9H-xanthen-9-one-2-carboxylic acids are described. Antiallergic activity was evaluated in the rat passive cutaneous anaphylaxis (PCA) screen. Biological results were analyzed using regression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6eb99e561437d145df69136c3bb812a
https://doi.org/10.1002/chin.197919261
https://doi.org/10.1002/chin.197919261
Publikováno v:
Archives of biochemistry and biophysics. 194(2)
Quantitative structure-activity relationships have been formulated for the inhibition of dihydrofolate reductase from bovine and rat liver by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-X-phenyl)-s-triazines. The best correlations are: bovine, log 1 C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6714686b63c8d96eaa12c18e00f35eab
https://pubmed.ncbi.nlm.nih.gov/443823
https://pubmed.ncbi.nlm.nih.gov/443823
Publikováno v:
Journal of medicinal chemistry. 19(5)
A quantitative structure-activity relationship (QSAR) has been formulated for quinazolines causing 50% inhibition of liver dihydrofolate reductase. The QSAR for the quinazolines is compared with QSAR for triazine and pyrimidine inhibitors. The three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235b8964bf8a6b6734b61e17b1857c84
https://pubmed.ncbi.nlm.nih.gov/1271401
https://pubmed.ncbi.nlm.nih.gov/1271401
Autor:
Robert W. Taft, James Y. Fukunaga
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f51f85dd598e08771074cad0ec14388
https://doi.org/10.1002/chin.197522083
https://doi.org/10.1002/chin.197522083