Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James Y Zou"'
Autor:
Zhi Huang, Gennifer E Merrihew, Eric B Larson, Jea Park, Deanna Plubell, Edward J Fox, Kathleen S Montine, C Dirk Keene, Caitlin S Latimer, James Y Zou, Michael J MacCoss, Thomas J Montine
Publikováno v:
Neuroscience Insights, Vol 18 (2023)
Studying proteomics data of the human brain could offer numerous insights into unraveling the signature of resilience to Alzheimer’s disease. In our previous study with rigorous cohort selection criteria that excluded 4 common comorbidities, we har
Externí odkaz:
https://doaj.org/article/e07e9497d19c47e4bdeb62f41890e0bf
Autor:
Amirata Ghorbani, David Ouyang, Abubakar Abid, Bryan He, Jonathan H. Chen, Robert A. Harrington, David H. Liang, Euan A. Ashley, James Y. Zou
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-10 (2020)
Abstract Echocardiography uses ultrasound technology to capture high temporal and spatial resolution images of the heart and surrounding structures, and is the most common imaging modality in cardiovascular medicine. Using convolutional neural networ
Externí odkaz:
https://doaj.org/article/914a9b08ef9d49d596f7dc8d8a6c2fa6
Autor:
J Weston Hughes, Neal Yuan, Bryan He, Jiahong Ouyang, Joseph Ebinger, Patrick Botting, Jasper Lee, John Theurer, James E. Tooley, Koen Nieman, Matthew P. Lungren, David H. Liang, Ingela Schnittger, Jonathan H. Chen, Euan A. Ashley, Susan Cheng, David Ouyang, James Y. Zou
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103613- (2021)
Background: Laboratory testing is routinely used to assay blood biomarkers to provide information on physiologic state beyond what clinicians can evaluate from interpreting medical imaging. We hypothesized that deep learning interpretation of echocar
Externí odkaz:
https://doaj.org/article/d63c1ebdec3940da9957bade5fd02847
Publikováno v:
Journal of the American Society of Echocardiography. 36:482-489
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db917bdee1cd654076890edf063e77a6
https://doi.org/10.1016/j.echo.2023.01.015
https://doi.org/10.1016/j.echo.2023.01.015
Publikováno v:
Information, Vol 13, Iss 1, p 15 (2021)
Interpretability is becoming an active research topic as machine learning (ML) models are more widely used to make critical decisions. Tabular data are one of the most commonly used modes of data in diverse applications such as healthcare and finance
Externí odkaz:
https://doaj.org/article/291c858522f94d45a8fb4147f15e2e37
Autor:
Zhi Huang, Gennifer E. Merrihew, Eric B. Larson, Jea Park, Deanna Plubell, Edward J. Fox, Kathleen S. Montine, Caitlin S. Latimer, C. Dirk Keene, James Y. Zou, Michael J. MacCoss, Thomas J. Montine
Publikováno v:
Nature Communications. 14
Resilience to Alzheimer’s disease is an uncommon combination of high disease burden without dementia that offers valuable insights into limiting clinical impact. Here we assessed 43 research participants meeting stringent criteria, 11 healthy contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0f0f683affd39566506b01929283a2
https://doi.org/10.1038/s41467-023-38376-x
https://doi.org/10.1038/s41467-023-38376-x
Autor:
Bryan He, Alan C. Kwan, Jae Hyung Cho, Neal Yuan, Charles Pollick, Takahiro Shiota, Joseph Ebinger, Natalie A. Bello, Janet Wei, Kiranbir Josan, Grant Duffy, Melvin Jujjavarapu, Robert Siegel, Susan Cheng, James Y. Zou, David Ouyang
Publikováno v:
Nature, vol 616, iss 7957
Artificial intelligence (AI) has been developed for echocardiography1–3, although it has not yet been tested with blinding and randomization. Here we designed a blinded, randomized non-inferiority clinical trial (ClinicalTrials.gov ID: NCT05140642;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e16d95e9d6d33e4561a35c7dc343891
https://escholarship.org/uc/item/3qk1p4hn
https://escholarship.org/uc/item/3qk1p4hn
Autor:
Zhi Huang, Gennifer E. Merrihew, Eric B. Larson, Jea Park, Deanna Plubell, Edward J. Fox, Kathleen S. Montine, C. Dirk Keene, James Y. Zou, Michael J. MacCoss, Thomas J. Montine
Resilience to Alzheimer’s disease (RAD) is an uncommon combination of high disease burden without dementia that may provide critical insights into limiting the clinical impact of this incurable disease. In this study, we used mass spectrometry-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbea24f3e722e21b99847cb9192db13e
https://doi.org/10.1101/2022.10.09.511430
https://doi.org/10.1101/2022.10.09.511430
Autor:
Grant Duffy, Paul P. Cheng, Neal Yuan, Bryan He, Alan C. Kwan, Matthew J. Shun-Shin, Kevin M. Alexander, Joseph Ebinger, Matthew P. Lungren, Florian Rader, David H. Liang, Ingela Schnittger, Euan A. Ashley, James Y. Zou, Jignesh Patel, Ronald Witteles, Susan Cheng, David Ouyang
Publikováno v:
JAMA cardiology. 7(4)
Early detection and characterization of increased left ventricular (LV) wall thickness can markedly impact patient care but is limited by under-recognition of hypertrophy, measurement error and variability, and difficulty differentiating causes of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93bd7e9cf576a3f680ac3f91b27616b
https://pubmed.ncbi.nlm.nih.gov/35195663
https://pubmed.ncbi.nlm.nih.gov/35195663
Autor:
Edward Bedoya, Elliott Kieff, John Quackenbush, Kaoru Takasaki, Jessica C. Mar, James Y. Zou, Megha Padi, Benjamin E. Gewurz, Bo Zhao, Ellen Cahir-McFarland, Nicholas P. Shinners
Publikováno v:
Journal of Virology. 85:6764-6773
Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) transforms rodent fibroblasts and is expressed in most EBV-associated malignancies. LMP1 ( t ransformation e ffector s ite 2 [TES2]/C-terminal activation region 2 [CTAR2]) activates NF-κB, p3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c63903713af290d586874e53daca0b4
https://doi.org/10.1128/jvi.00422-11
https://doi.org/10.1128/jvi.00422-11