Zobrazeno 1 - 10
of 14
pro vyhledávání: '"James X. Du"'
Autor:
Zhiqiang Wang, Shimeng Cheng, Zhenxing Wang, Guang Shi, Jiwei Chen, Jiwen Li, Shwu Yuan Wu, Jinke Cheng, Nansong Xia, Tieliu Shi, Jiemin Wong, Dong Wang, Cheng Ming Chiang, Lujian Liao, James X. Du, Yu Peng, Yunhao Zhai, Sheng-Zhong Duan, Fang Yu
Publikováno v:
Cell Research. 28:670-685
Regulation of transcription is fundamental to the control of cellular gene expression and function. Although recent studies have revealed a role for the oncoprotein MYC in amplifying global transcription, little is known as to how the global transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd90ecc69d3a8f02e69003c48a112c2
https://doi.org/10.1038/s41422-018-0023-9
https://doi.org/10.1038/s41422-018-0023-9
Autor:
Xiaoguang Liu, Qiufang Zeng, Lujian Liao, Shennan Gao, Bin Tang, Jiemin Wong, Wei Wei, Jiwen Li, Wenpeng Li, James X. Du, Lu Lu, Anqi Mao
Publikováno v:
Journal of Proteome Research. 16:1743-1752
Lysine crotonylation on histones is a recently identified post-translational modification that has been demonstrated to associate with active promoters and to directly stimulate transcription. Given that crotonyl-CoA is essential for the acyl transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f6de79bd17918870b848f942a1ef69
https://doi.org/10.1021/acs.jproteome.7b00012
https://doi.org/10.1021/acs.jproteome.7b00012
Autor:
Shuman Gao, Wencai Wang, Jiemin Wong, James X. Du, Xueli Hu, Jiwen Li, Zhiqiang Wang, Xin-Hua Feng, Peilin Chen
Lysine methylation of chromosomal and nuclear proteins is a well-known mechanism of epigenetic regulation, but relatively little is known about the role of this protein modification in signal transduction. Using an RNAi-based functional screening of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0bd5a740d2ddc5cd51b33854ba3842
https://europepmc.org/articles/PMC5535043/
https://europepmc.org/articles/PMC5535043/
Autor:
Jin-Qiu Zhou, Xiaoguang Liu, Xueli Yang, Jian Wu, Jiwen Li, Wei Wei, Jiemin Wong, Qiao Zhang, Yang Zhang, Yingming Zhao, Tieliu Shi, Yu-Ting Liu, Ming Lei, James X. Du
Publikováno v:
Cell Discovery
Recent studies indicate that histones are subjected to various types of acylation including acetylation, propionylation and crotonylation. CBP and p300 have been shown to catalyze multiple types of acylation but are not conserved in evolution, raisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ca285f846fc7bb17c3c6b5052615e2
https://doi.org/10.1038/celldisc.2017.16
https://doi.org/10.1038/celldisc.2017.16
Autor:
Meng Wu, Jiemin Wong, Wei Wei, Jiwen Li, Rong Cong, Tieliu Shi, James X. Du, Jiwei Chen, Philippe Bouvet
Publikováno v:
Science China. Life sciences. 60(6)
Histone methylation is believed to provide binding sites for specific reader proteins, which translate histone code into biological function. Here we show that a family of acidic domain-containing proteins including nucleophosmin (NPM1), pp32, SET/TA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcd0edcd4b2703d26e776d7d4c21aa1
https://pubmed.ncbi.nlm.nih.gov/28194553
https://pubmed.ncbi.nlm.nih.gov/28194553
Autor:
Ling Zhang, Yufeng Tong, James X. Du, Jiemin Wong, Ping Wang, Jiwen Li, Lan Fang, Wei Wei, Xueling Jin
Publikováno v:
Molecular Cell. 55:537-551
Sox2 is a key factor for maintaining embryonic stem cell (ESS) pluripotency, but little is known about its posttranslational regulation. Here we present evidence that the precise level of Sox2 proteins in ESCs is regulated by a balanced methylation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a0e2112ce766776d5fce47366539eb
https://doi.org/10.1016/j.molcel.2014.06.018
https://doi.org/10.1016/j.molcel.2014.06.018
Autor:
Wenqiang Yu, Fei Li, Junying Zhang, Taiping Chen, Hongbin Ji, Haijun Zhu, Liangliang Xu, Jiwen Li, Qihan Wu, Yuanhui Jia, Lan Fang, Jialun Li, James X. Du, Jiemin Wong, Yan Li, Pishun Li, Jackie J.D. Han, Yan Feng, Ruiping Wang, Hao Cheng
Publikováno v:
Cell Discovery
Global DNA hypomethylation is a most common epigenetic alteration in cancer, but the mechanism remains elusive. Previous studies demonstrate that UHRF1 but not UHRF2 is required for mediating DNA maintenance methylation by DNMT1. Here we report unexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740b7115446e95120bf33ad765aeeb7e
https://doi.org/10.1038/celldisc.2016.7
https://doi.org/10.1038/celldisc.2016.7
Autor:
Vincent W. Yang, Mandayam O. Nandan, James X. Du, Engda G. Hagos, Agnieszka Bialkowska, Bing Yu
Publikováno v:
Journal of Biological Chemistry. 286:40354-40364
The zinc finger transcription factor Krüppel-like factor 5 (KLF5) is regulated posttranslationally. We identified SMAD ubiquitination regulatory factor 2 (SMURF2), an E3 ubiquitin ligase, as an interacting protein of KLF5 by yeast two-hybrid screen,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f03407a17dafc5eb29534bad05049ef
https://doi.org/10.1074/jbc.m111.258707
https://doi.org/10.1074/jbc.m111.258707
Publikováno v:
Journal of Biological Chemistry. 285:28298-28308
The zinc finger transcription factor, Krüppel-like factor 4 (KLF4), regulates numerous biological processes, including proliferation, differentiation, and embryonic stem cell self-renewal. Although the DNA sequence to which KLF4 binds is established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8171d45327a72fbcef14cae1cf570739
https://doi.org/10.1074/jbc.m110.101717
https://doi.org/10.1074/jbc.m110.101717
Publikováno v:
Journal of Biological Chemistry. 283:31991-32002
SUMOylation is a form of post-translational modification shown to control nuclear transport. Krüppel-like factor 5 (KLF5) is an important mediator of cell proliferation and is primarily localized to the nucleus. Here we show that mouse KLF5 is SUMOy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03578b1f9b52c9c13a27f03a8040400b
https://doi.org/10.1074/jbc.m803612200
https://doi.org/10.1074/jbc.m803612200