Zobrazeno 1 - 10
of 10
pro vyhledávání: '"James X Sun"'
Autor:
James X Sun, Yuting He, Eric Sanford, Meagan Montesion, Garrett M Frampton, Stéphane Vignot, Jean-Charles Soria, Jeffrey S Ross, Vincent A Miller, Phil J Stephens, Doron Lipson, Roman Yelensky
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1005965 (2018)
A key constraint in genomic testing in oncology is that matched normal specimens are not commonly obtained in clinical practice. Thus, while well-characterized genomic alterations do not require normal tissue for interpretation, a significant number
Externí odkaz:
https://doaj.org/article/2c3540ac65e64877b4ea2ae6249ea3de
Autor:
Christine M. Lovly, Jeffrey A. Sosman, Ryan J. Sullivan, Philip J. Stephens, Vincent A. Miller, Yu Shyr, Harlan Robins, Catherine Sanders, Jeffrey S. Ross, Justin M. Cates, Justin M. Balko, Igor Puzanov, Dennie T. Frederick, Yuting He, James X. Sun, Sohail Balasubramanian, Siraj M. Ali, Joel Greenbowe, Zachary R. Chalmers, David Fabrizio, Riley C. Ennis, Xingyi Guo, Yaomin Xu, Erik Yusko, Matthew J. Rioth, Garrett M. Frampton, Douglas B. Johnson
Therapeutic antibodies blocking programmed death-1 and its ligand (PD-1/PD-L1) induce durable responses in a substantial fraction of melanoma patients. We sought to determine whether the number and/or type of mutations identified using a next-generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15363619a8ba34271f174c2683420406
https://doi.org/10.1158/2326-6066.c.6548372.v1
https://doi.org/10.1158/2326-6066.c.6548372.v1
Autor:
Christine M. Lovly, Jeffrey A. Sosman, Ryan J. Sullivan, Philip J. Stephens, Vincent A. Miller, Yu Shyr, Harlan Robins, Catherine Sanders, Jeffrey S. Ross, Justin M. Cates, Justin M. Balko, Igor Puzanov, Dennie T. Frederick, Yuting He, James X. Sun, Sohail Balasubramanian, Siraj M. Ali, Joel Greenbowe, Zachary R. Chalmers, David Fabrizio, Riley C. Ennis, Xingyi Guo, Yaomin Xu, Erik Yusko, Matthew J. Rioth, Garrett M. Frampton, Douglas B. Johnson
Supplementary Table 1: Results for samples obtained (less than or equal to) 12 months prior to therapy (optimal) vs. those obtained >12 months from treatment or shortly after starting therapy (non-optimal). Supplementary Table 2: Cox proportional haz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938003187c5e8f00cf881b1a4f681805
https://doi.org/10.1158/2326-6066.22537262
https://doi.org/10.1158/2326-6066.22537262
Autor:
Elizabeth M. Swisher, Iain A. McNeish, Thomas C. Harding, James D. Brenton, Heidi Giordano, James X. Sun, Robert L. Coleman, Gottfried E. Konecny, Clare L. Scott, Scott H. Kaufmann, Setsuko K. Chambers, David M. O'Malley, Lara Maloney, Jeffrey D. Isaacson, Elaina Mann, Lan-Thanh Vo, Carmen Say, Marc R. Radke, Elena Helman, Anna V. Tinker, Isabelle Ray-Coquard, Ana Oaknin, Amit M. Oza, Maria I. Harrell, Kevin K. Lin
Table S2 shows data concerning the association between baseline characteristics and presence of BRCA reversion mutations in pretreatment circulating cell-free DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5b7336d23449439404d62f9040a376
https://doi.org/10.1158/2159-8290.22532687.v1
https://doi.org/10.1158/2159-8290.22532687.v1
Autor:
Elizabeth M. Swisher, Iain A. McNeish, Thomas C. Harding, James D. Brenton, Heidi Giordano, James X. Sun, Robert L. Coleman, Gottfried E. Konecny, Clare L. Scott, Scott H. Kaufmann, Setsuko K. Chambers, David M. O'Malley, Lara Maloney, Jeffrey D. Isaacson, Elaina Mann, Lan-Thanh Vo, Carmen Say, Marc R. Radke, Elena Helman, Anna V. Tinker, Isabelle Ray-Coquard, Ana Oaknin, Amit M. Oza, Maria I. Harrell, Kevin K. Lin
A key resistance mechanism to platinum-based chemotherapies and PARP inhibitors in BRCA-mutant cancers is the acquisition of BRCA reversion mutations that restore protein function. To estimate the prevalence of BRCA reversion mutations in high-grade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c393b81f60afdff6fe8e9b164e1dfd80
https://doi.org/10.1158/2159-8290.c.6546800.v1
https://doi.org/10.1158/2159-8290.c.6546800.v1
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Long tail distribution of the top 50 altered genes in pediatric sarcoma (S1); Long tail distribution of the top 50 altered genes in pediatric extracranial embryonal tumors (S2); Long tail distribution of the top 50 altered genes in pediatric brain tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1787586c646efaf2a677928246eca2
https://doi.org/10.1158/0008-5472.22414374
https://doi.org/10.1158/0008-5472.22414374
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Gene lists for Version 1 of the FoundationOne Assay (S1); Gene lists for Version 2 of the FoundationOne Assay (S2); Gene lists for Version 3 of the FoundationOne Assay (S3); Gene lists for Version 4 of the FoundationOne Assay (S4); Gene lists for Ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d519b7259eab3f249fe92b2affbb4a8
https://doi.org/10.1158/0008-5472.22414371.v1
https://doi.org/10.1158/0008-5472.22414371.v1
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Pediatric cancers are generally characterized by low mutational burden and few recurrently mutated genes. Recent studies suggest that genomic alterations may help guide treatment decisions and clinical trial selection. Here, we describe genomic profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da4fd89d6550e13c627bd12d2463218
https://doi.org/10.1158/0008-5472.c.6508959.v1
https://doi.org/10.1158/0008-5472.c.6508959.v1
Publikováno v:
Prof. Mark via Courtney Crummett
Objective: The value of different algorithms that estimate cardiac output (CO) by analysis of a peripheral arterial blood pressure (ABP) waveform has not been definitively identified. In this investigation, we developed a testing data set containing
Publikováno v:
BMC Health Services Research
Background As of October 1, 2012, hospitals in the United States with excess readmissions based on the Centers for Medicare and Medicaid Services (CMS) risk-adjusted ratio began being penalized. Given the impact of high readmission rates to hospitals