Zobrazeno 1 - 10
of 643
pro vyhledávání: '"James West"'
Autor:
Megha Talati, Evan Brittain, Vineet Agrawal, Niki Fortune, Katie Simon, Sheila Shay, Xiaofang Zeng, Michael L. Freeman, James West, Anna Hemnes
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionPulmonary arterial hypertension is a fatal cardiopulmonary disease. Leptin, a neuroendocrine hormone released by adipose tissue, has a complex relationship with cardiovascular diseases, including PAH. Leptin is thought to be an important
Externí odkaz:
https://doaj.org/article/18126b69c87e4ec29b237f8c7e6df4a2
Autor:
Louise S. Matheson, Georg Petkau, Beatriz Sáenz-Narciso, Vanessa D’Angeli, Jessica McHugh, Rebecca Newman, Haydn Munford, James West, Krishnendu Chakraborty, Jennie Roberts, Sebastian Łukasiak, Manuel D. Díaz-Muñoz, Sarah E. Bell, Sarah Dimeloe, Martin Turner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-24 (2022)
Abstract The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in CD4+ T cells have focussed largely on cytokines, but their impa
Externí odkaz:
https://doaj.org/article/502be5987af14790b105142b3363eb12
Publikováno v:
Sensors, Vol 22, Iss 23, p 9530 (2022)
Coronavirus disease 2019 (COVID-19) has led to countless deaths and widespread global disruptions. Acoustic-based artificial intelligence (AI) tools could provide a simple, scalable, and prompt method to screen for COVID-19 using easily acquirable ph
Externí odkaz:
https://doaj.org/article/fd0fe57611f348fe95035b1de662e902
Autor:
James West
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/0b29a58946074d61a7604f099bd8d4c6
Autor:
Evan L. Brittain, Kevin Niswender, Vineet Agrawal, Xinping Chen, Run Fan, Meredith E. Pugh, Todd W. Rice, Ivan M. Robbins, Haocan Song, Christopher Thompson, Fei Ye, Chang Yu, He Zhu, James West, John H. Newman, Anna R. Hemnes
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 22 (2020)
Background Metabolic dysfunction is highly prevalent in pulmonary arterial hypertension (PAH) and likely contributes to both pulmonary vascular disease and right ventricular (RV) failure in part because of increased oxidant stress. Currently, there i
Externí odkaz:
https://doaj.org/article/6afa9ff7a56e4bc1a57e9254ceab5a30
Autor:
Albert Kwok, Ilona Zvetkova, Sam Virtue, Ineke Luijten, Isabel Huang-Doran, Patsy Tomlinson, David A. Bulger, James West, Steven Murfitt, Julian Griffin, Rafeah Alam, Daniel Hart, Rachel Knox, Peter Voshol, Antonio Vidal-Puig, Jørgen Jensen, Stephen O'Rahilly, Robert K. Semple
Publikováno v:
Molecular Metabolism, Vol 40, Iss , Pp 101020- (2020)
Objective: Insulin signalling via phosphoinositide 3-kinase (PI3K) requires PIK3R1-encoded regulatory subunits. C-terminal PIK3R1 mutations cause SHORT syndrome, as well as lipodystrophy and insulin resistance (IR), surprisingly without fatty liver o
Externí odkaz:
https://doaj.org/article/82f6d95279d840059ee0a0ab5c79af2b
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammato
Externí odkaz:
https://doaj.org/article/b2ca2ce95abf40f3b2c721c1b28ad58a
Autor:
Alexandria Vingino, Marilyn C. Roberts, Michelle Wainstein, James West, Stephanie A. Norman, Dyanna Lambourn, Jeffery Lahti, Ryan Ruiz, Marisa D’Angeli, Scott J. Weissman, Peter Rabinowitz
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1201 (2021)
E. coli was isolated from the Salish Sea (Puget Sound) ecosystem, including samples of marine and fresh water, and wildlife dependent on this environment. E. coli isolates were assessed for phenotypic and genotypic resistance to antibiotics. A total
Externí odkaz:
https://doaj.org/article/4eecdf8f050c43388aaa9e98b0923aeb
Autor:
James West, Anandharajan Rathinasabapathy, Xinping Chen, Sheila Shay, Shanti Gladson, Megha Talati
Publikováno v:
Cells, Vol 10, Iss 9, p 2306 (2021)
Pulmonary arterial hypertension (PAH) is a progressive lung disease caused by thickening of the pulmonary arterial wall and luminal obliteration of the small peripheral arteries leading to increase in vascular resistance which elevates pulmonary arte
Externí odkaz:
https://doaj.org/article/aa1d05f70b594ca4b5fa3e08a43e797c
Autor:
Catherine E. Vrentas, Justin J. Greenlee, Gregory H. Foster, James West, Marianna M. Jahnke, Mark T. Schmidt, Eric M. Nicholson
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Abstract Objective The most common hereditary prion disease is human Creutzfeldt-Jakob disease (CJD), associated with a mutation in the prion gene resulting in a glutamic acid to lysine substitution at position 200 (E200K) in the prion protein. Model
Externí odkaz:
https://doaj.org/article/02210c54df0d461aaa1016c0c3eab482