Zobrazeno 1 - 9
of 9
pro vyhledávání: '"James Waire"'
Autor:
Sharon R. Nahill, Russell Bigelow, Lan Gao, James Waire, John L. Dzuris, Abraham Scaria, Melanie Ruzek, John M. Williams
Publikováno v:
Transplantation. 84:S27-S34
A murine anti-thymocyte globulin, which was made in rabbits using the same manufacturing protocol used in production of Thymoglobulin (Genzyme Transplant, Cambridge, MA), was used to explore the biology and mechanism of action of Thymoglobulin. These
Autor:
Tim Edmunds, Scott M. Van Patten, Heather Hughes, Michael R. Huff, Peter A. Piepenhagen, David Reczek, James Waire, Paul V. Ward, Huawei Qiu, Chandrashekar Ganesa, Joseph P. Kutzko
Publikováno v:
Glycobiology. 17:467-478
Recombinant human glucocerebrosidase (imiglucerase, Cerezyme ® ) is used in enzyme replacement therapy for Gaucher disease. Complex oligosaccharides present on Chinese hamster ovary cell-expressed glucocerebrosidase (GCase) are enzymatically remodel
Autor:
Mark R. Lucier, Rachel E. Thompson, James Waire, Athena W. Lin, Barbara A. Osborne, Richard A. Goldsby
Publikováno v:
The Journal of Immunology. 161:5438-5444
Ig repertoire diversification in cattle was studied in the ileal Peyer’s patch (IPP) follicles of young calves and in the spleens of late first-trimester bovine fetuses. To investigate follicular diversification, individual IPP follicles were isola
Autor:
Carol A. Nelson, Robert Pawliuk, Douglas Matthews, Richard D. Garman, Melanie Ruzek, Arden Bond, Michael L. Hawes, Beth L. Thurberg, Scott Lonning, Allison Vitsky, James Waire, Emily R. LaCasse, Peter A. Piepenhagen, Steve Ledbetter, Laura Andrews, Susan M. Richards
Publikováno v:
The American journal of pathology. 174(6)
Transforming growth factor-beta (TGF-beta) is a pleiotropic growth factor; its overexpression has been implicated in many diseases, making it a desirable target for therapeutic neutralization. In initial safety studies, mice were chronically treated
Autor:
Scott Vanpatten, James M. Murray, James Waire, Heather Hughes, Laura Andrews, Peter A. Piepenhagen, Michael O'Callaghan, Tim Edmunds, Beth L. Thurberg
Publikováno v:
Microscopy Research and Technique.
Efficient targeting of therapeutic reagents to tissues and cell types of interest is critical to achieving therapeutic efficacy and avoiding unwanted side effects due to offtarget uptake. To increase assay efficiency and reduce the number of animals
Autor:
Deborah A. Hopkins, Richard D. Garman, Srinivas Shankara, John M. Williams, James Waire, Bruce L. Roberts, Susan M. Richards, Gina Lacorcia, Jennifer Sullivan, Melanie Ruzek, John L. Dzuris, Sharon R. Nahill, Abraham Scaria
Publikováno v:
Blood. 111(3)
Antithymocyte/antilymphocyte globulins are polyclonal antihuman T-cell antibodies used clinically to treat acute transplant rejection. These reagents deplete T cells, but a rabbit antihuman thymocyte globulin has also been shown to induce regulatory
Autor:
Abraham Scaria, Susan M. Richards, James Waire, Allison Vitsky, Melanie Ruzek, Gary A. White, Richard D. Garman, Patty Ewing
Publikováno v:
Clinical Immunology. 127:S114
Autor:
James Waire, Richard D. Garman, William Weber, John M. Williams, Melanie Ruzek, Susan M. Richards
Publikováno v:
Blood. 110:3251-3251
Rabbit anti-human thymocyte globulins (ATG) (Thymoglobulin®) are widely used for treatment and prevention of solid organ transplant rejection. However, more recently these therapies have been shown to also reduce the severity of graft-versus-host di
Autor:
Scott M. Van Patten, Heather Hughes, Michael R. Huff, Peter A. Piepenhagen, James Waire, Huawei Qiu, Chandrashekar Ganesa, David Reczek, Paul V. Ward, Joseph P. Kutzko, Tim Edmunds
Publikováno v:
Glycobiology; May2007, Vol. 17 Issue 5, p467-467, 1p