Zobrazeno 1 - 6
of 6
pro vyhledávání: '"James W. van der Wolde"'
Autor:
James W. van der Wolde, Victor G. Puelles, Luise A. Cullen-McEwen, James A. Armitage, Jan Czogalla, Fabian Haas, Kotaro Haruhara, Leon Tribolet, Yusuke Okabayashi, John F. Bertram, John P. Dowling, Wendy E. Hoy, M. Jane Black, Robert De Matteo, Michael G. Bertram
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F322-F334
The present study shows, for the first time, that low birth weight as a result of maternal nutrition is associated with low podocyte endowment. However, a mild podocyte deficit at birth did not result in glomerular pathology in adulthood. In contrast
Autor:
John F. Bertram, Karen M. Moritz, Luise A. Cullen-McEwen, Sarah L. Walton, Gessica D Gonçalves, Sarah E Gazzard, Paulo Cezar de Freitas Mathias, James W. van der Wolde
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007)REFERENCES. 303(10)
Fetal hypoxia is a common complication of pregnancy. We have previously reported that maternal hypoxia in late gestation in mice gives rise to male offspring with reduced nephron number, while females have normal nephron number. Male offspring later
Autor:
Tillmann Bork, Tobias B. Huber, Leon Tribolet, Fabian Braun, Rafael Kramann, Yu Bo Yang Sun, Wendy E. Hoy, Gerhard Müller-Newen, Peter G. Kerr, Christoph Kuppe, Maja T. Lindenmeyer, Nicola Wanner, Thorsten Wiech, Luc Furic, Sharon D. Ricardo, Milagros N. Wong, Clemens D. Cohen, Victor G. Puelles, Lukas Gernhold, Marcus J. Moeller, Michelle M Kett, David J. Nikolic-Paterson, Jinhua Li, Fermin Person, Markus W. Scheppach, James W. van der Wolde, Turgay Saritas, Kate M. Denton, Claudia R.C. van Roeyen, Richard J. Rebello, Michael D Hughson, John F. Bertram, Luise A. Cullen-McEwen
Publikováno v:
JCI Insight
The cellular origins of glomerulosclerosis involve activation of parietal epithelial cells (PECs) and progressive podocyte depletion. While mammalian target of rapamycin–mediated (mTOR-mediated) podocyte hypertrophy is recognized as an important si
Autor:
David J. Nikolic-Paterson, Stephen Firth, Milagros N. Wong, Georgina Caruana, Stacey Hokke, Luise A. Cullen-McEwen, James W. van der Wolde, Victor G. Puelles, Ian S. Harper, Keith E. Schulze, John F. Bertram, Jonathan G Bensley, Kieran M. Short, Jinhua Li
Publikováno v:
Journal of the American Society of Nephrology. 27:3093-3104
Podocyte depletion is sufficient for the development of numerous glomerular diseases and can be absolute (loss of podocytes) or relative (reduced number of podocytes per volume of glomerulus). Commonly used methods to quantify podocyte depletion intr
Autor:
Sarah E Gazzard, Luise A. Cullen-McEwen, John F. Bertram, Michael G. Bertram, Kotaro Haruhara, Sarah L. Walton, Karen M. Moritz, James W. van der Wolde, Gessica D Gonçalves
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Marc Spehr, Gerhard Müller-Newen, Felix Heymann, Christoph Kuppe, Leon Decker, Fabian Braun, Rafael Kramann, Sylvia Menzel, Christian Kurts, Peter Boor, David Fleck, Astrid Fuss, Stella Papadouri, Lena Ortz, Marcus J. Moeller, James W. van der Wolde, John F. Bertram, Hiroki R. Ueda, Victor G. Puelles, Etsuo A. Susaki, David J. Nikolic-Paterson, Turgay Saritas, Barbara M. Klinkhammer, Oliver Kretz, Jürgen Floege, Alexander M.C. Böhner, Thiago Strieder, Michael Vogt, Tobias B. Huber
Publikováno v:
Kidney international 96(2), 505-516 (2019). doi:10.1016/j.kint.2019.02.034
Recent developments in optical tissue clearing have been difficult to apply for the morphometric analysis of organs with high cellular content and small functional structures, such as the kidney. Here, we establish combinations of genetic and immuno-