Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James W. Spurlin"'
Autor:
Samantha R. Coy, Budi Utama, James W. Spurlin, Julia G. Kim, Harshavardhan Deshmukh, Peter Lwigale, Keizo Nagasaki, Adrienne M. S. Correa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Half of the marine virosphere is hypothesized to be RNA viruses (kingdom Orthornavirae) that infect abundant micro-eukaryotic hosts (e.g. protists). To test this, quantitative approaches that broadly track infections in situ are needed. Here
Externí odkaz:
https://doaj.org/article/1d5b368db1e4425e890e0fefa62a1788
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Often acute damage to the cornea initiates drastic tissue remodeling, resulting in fibrotic scarring that disrupts light transmission and precedes vision impairment. Very little is known about the factors that can mitigate fibrosis and promo
Externí odkaz:
https://doaj.org/article/49dabc7559824e979a4f2c8fa2f71535
Autor:
Daniel Tzou, James W. Spurlin, Amira L. Pavlovich, Carolyn R. Stewart, Jason P. Gleghorn, Celeste M. Nelson
Publikováno v:
EvoDevo, Vol 7, Iss 1, Pp 1-7 (2016)
Abstract Background New branches within the embryonic chicken lung form via apical constriction, in which epithelial cells in the primary bronchus become trapezoidal in shape. These branches form at precise locations along the primary bronchus that s
Externí odkaz:
https://doaj.org/article/6fd5c2029a5847a2baac2a54f74164db
Autor:
James W. Spurlin, James V. Jester, Elena Koudouna, Peter Y. Lwigale, Anna Babushkina, Andrew J. Quantock
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Wound healing is characterized by cell and extracellular matrix changes mediating cell migration, fibrosis, remodeling and regeneration. We previously demonstrated that chick fetal wound healing shows a regenerative phenotype regarding the cellular a
Autor:
Jacob M. Jaslove, Katharine Goodwin, Aswin Sundarakrishnan, James W. Spurlin, Sheng Mao, Andrej Košmrlj, Celeste M. Nelson
Publikováno v:
Development
During development, the mammalian lung undergoes several rounds of branching, the rate of which is tuned by the relative pressure of the fluid within the lumen of the lung. We carried out bioinformatics analysis of RNA-sequencing of embryonic mouse l
During development, cells aggregate at tissue boundaries to form normal tissue architecture of organs. However, how cells are segregated into tissue precursors remains largely unknown. Cornea development is a perfect example of this process whereby n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5b1b4c9a3aeebe17295bb8d302e6bd
https://doi.org/10.1101/2021.10.13.464255
https://doi.org/10.1101/2021.10.13.464255
Autor:
James W. Spurlin, Sahana Jayaraman, Celeste M. Nelson, Mei-Fong Pang, Michael J. Siedlik, Rawlison Zhang, Bryan A. Nerger
Publikováno v:
Development
Reciprocal epithelial-mesenchymal signaling is essential for morphogenesis, including branching of the lung. In the mouse, mesenchymal cells differentiate into airway smooth muscle that wraps around epithelial branches, but this contractile tissue is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62c11247d35e547b3633007c117797d
https://europepmc.org/articles/PMC6737900/
https://europepmc.org/articles/PMC6737900/
Autor:
Celeste M. Nelson, James W. Spurlin
Branched networks are ubiquitous throughout nature, particularly found in tissues that require large surface area within a restricted volume. Many tissues with a branched architecture, such as the vasculature, kidney, mammary gland, lung and nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b357f10f86d91f70a9f1c823e4346a85
https://europepmc.org/articles/PMC5379029/
https://europepmc.org/articles/PMC5379029/
Publikováno v:
Developmental Biology. 391:241-250
Corneal avascularity is important for optical clarity and normal vision. However, the molecular mechanisms that prevent angioblast migration and vascularization of the developing cornea are not clear. Previously we showed that periocular angioblasts
Autor:
Peter Y. Lwigale, James W. Spurlin
Publikováno v:
Developmental Dynamics. 242:148-154
Background: During early development, avian embryos are easily accessible in ovo for transplantations and experimental perturbations. However, these qualities of the avian embryonic model rapidly wane shortly after embryonic day (E)4 when the embryo