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of 3
pro vyhledávání: '"James W. Southwell"'
Autor:
James W. Southwell, Reyme Herman, Daniel J. Raines, Justin E. Clarke, Isabelle Böswald, Thorsten Dreher, Sophie M. Gutenthaler, Nicole Schubert, Jana Seefeldt, Nils Metzler‐Nolte, Gavin H. Thomas, Keith S. Wilson, Anne‐Kathrin Duhme‐Klair
Publikováno v:
Chemistry – A European Journal. 29
Due to rising resistance, new antibacterial strategies are needed, including methods for targeted antibiotic release. As targeting vectors, chelating molecules released by bacteria to acquire iron called siderophores have been investigated for conjug
Publikováno v:
ChemMedChem. 16(7)
The field of antibacterial siderophore conjugates, referred to as Trojan Horse antibacterials, has received increasing attention in recent years, driven by the rise of antimicrobial resistance. Trojan Horse antibacterials offer an opportunity to expl
Autor:
Eszter Boros, Ellis J. Wilde, Anne Routledge, Conor M. Black, Anne-Kathrin Duhme-Klair, Apurva Pandey, James W. Southwell, Reyme Herman, Gavin H. Thomas, Thomas J. Sanderson
A novel ciprofloxacin-siderophore Trojan Horse antimicrobial was prepared by incorporating key design features of salmochelin S4, a stealth siderophore that evades mammalian siderocalin capture via its glycosylated catechol units. As-sessment of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fb5caca9fe56330a2161a740d53d39
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf