Zobrazeno 1 - 10
of 32
pro vyhledávání: '"James W. Sharp"'
Publikováno v:
The Journal of Nutrition. 148:480-489
Background Low protein amounts are used in ketogenic diets (KDs), where an essential (indispensable) amino acid (IAA) can become limiting. Because the chemically sensitive, seizurogenic, anterior piriform cortex (APC) is excited by IAA limitation, an
Publikováno v:
Diabetes. 68
Diabetes mellitus (DM) is the 7th leading cause of death in the U.S. in 2015. According to Center of Disease Control (CDC), prevalence of DM has increased in recent years affecting 9.4% of U.S. population and 12.5% of New York City (NYC) population i
Publikováno v:
Diabetes. 68
Diabetes mellitus (DM) and prediabetes incidence have increased in the U.S. in recent years. In our center we have observed higher prevalence of diabetes/prediabetes in NYC Chinese-Americans than the general population. Diabetes patients are often as
Autor:
Dorothy W. Gietzen, John B. Rudell, John A. Payne, Irène Baccelli, Catherine Ross-Inta, James W. Sharp
Publikováno v:
Journal of neurochemistry, vol 127, iss 4
The anterior piriform cortex (APC) is activated by, and is the brain area most sensitive to, essential (indispensable) amino acid (IAA) deficiency. The APC is required for the rapid (20 min) behavioral rejection of IAA deficient diets and increased f
Publikováno v:
Neurogastroenterology & Motility. 23:e282-e293
Background Lumenal glucose initiates changes in gastrointestinal (GI) function, including inhibition of gastric emptying, stimulation of pancreatic exocrine and endocrine secretion, and intestinal fluid secretion. Glucose stimulates the release of GI
Publikováno v:
Endocrinology. 148:1954-1962
Glucagon-like peptide-2 (GLP-2) is a nutrient-dependent proglucagon-derived hormone that stimulates intestinal growth through poorly understood paracrine and/or neural pathways. The relationship between GLP-2 action and a vagal pathway is unclear. Ou
Autor:
Jörg Glatzle, Helen E. Raybould, Samara L. Freeman, Catia Sternini, James W. Sharp, Carla Robin, Melissa Valdellon
Publikováno v:
Gastroenterology. 131:97-107
Background & Aims: Release of 5-hydroxytryptamine (5-HT) from mucosal enterochromaffin cells and activation of 5-HT3 receptors (5-HT3Rs) on neurons in the gut wall is important in the response of the gut to the luminal environment. Intestinal inflamm
Publikováno v:
The Journal of Comparative Neurology. 494:485-494
The anterior piriform cortex (APC) has been shown to be an essential brain structure for the detection of dietary indispensable amino acid (IAA) deficiency, but little has been known about possible molecular detection mechanisms. Increased phosphoryl
Autor:
Kevin Carter, Darryle D. Schoepp, Jon P. Williams, Melinda Reilly, Floyd R. Sallee, James W. Sharp, Frank R. Sharp, Nicole R. Herring, Jon Dickerson
Publikováno v:
Neuropharmacology. 47:1135-1145
The non-competitive NMDA receptor antagonists, including PCP (phencyclidine), ketamine, and MK-801 (dizocilpine) produce psychosis in humans and injure neurons in retrosplenial cortex in adult rodent brain. This study examined the effects of the meta
Publikováno v:
The Journal of Nutrition. 134:717-723
Sensing of indispensable amino acid (IAA) deficiency, an acute challenge to protein homeostasis, is demonstrated by rats as rejection of IAA-deficient diets within 20 min. The anterior piriform cortex (APC) of the brain in rats and birds is essential