Zobrazeno 1 - 10
of 32
pro vyhledávání: '"James W. Schilling"'
Publikováno v:
Gene. 98:225-230
To understand the pathological process by which amyloid is deposited in Alzheimer's disease, it is important to characterize the proteolytic processing events of the beta-amyloid precursor protein (beta-APP) from which the amyloid-forming fragment is
Autor:
Tatsuo Shinagawa, John D. Baxter, Cynthia Carilli, James W. Schilling, Willa A. Hsueh, Yung S. Do
Publikováno v:
Proceedings of the National Academy of Sciences. 87:1927-1931
Using pure recombinant human prorenin as a substrate, we have identified an enzyme in human kidney that accurately processes prorenin to active renin (EC 3.4.23.15). In the crude homogenate, the predominant activity of this potential renin-processing
Autor:
Jyoti Srivastava, Amy Lynn Sillman, Martin Baumgartner, Nikki Madson, Elizabeth Blackwood, James W. Schilling, Jocelyn H. Wright, Diane L. Barber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(36)
The mammalian Ste20-like Nck-interacting kinase (NIK) and its orthologs Misshapen in Drosophila and Mig-15 in Caenorhabditis elegans have a conserved function in regulating cell morphology, although through poorly understood mechanisms. We report two
Autor:
Axel Ullrich, Hongyang Wang, Irmi Sures, Zhengjun Chen, Alexei Kharitonenkov, James W. Schilling
Publikováno v:
Nature. 386(6621)
Phosphotyrosine phosphatases are critical negative or positive regulators in the intracellular signalling pathways that result in growth-factor-specific cell responses such as mitosis, differentiation, migration, survival, transformation or death. Th
Autor:
Yung-Mae M. Yao, James W. Schilling, Martin A. Smith, Fabio Rupp, Uel J. McMahan, Catherine Magill-Solc, Peter M. Snow
Publikováno v:
Molecular and cellular neurosciences. 3(5)
Agrin, the protein thought to trigger motor neuron-induced aggregation of postsynaptic molecules at the developing neuromuscular junction, has been purified from the synapse-rich electric organ of the marine ray. In order to study agrin's role in syn
Autor:
Allan C. Wilson, Thomas B. Lavoie, Ellen M. Prager, James W. Schilling, Sandra J. Smith-Gill, Lauren N.W. Kam-Morgan, Corey P. Mallett
Publikováno v:
Use of X-Ray Crystallography in the Design of Antiviral Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::538a245768b7bc8864c9305dac77b628
https://doi.org/10.1016/b978-0-12-438745-4.50022-7
https://doi.org/10.1016/b978-0-12-438745-4.50022-7
Autor:
D I Buckley, Samuel Hawgood, R T White, Philip L. Ballard, James W. Schilling, Bradley J. Benson, T M Crisp, John A. Clements, R G Warr
Publikováno v:
Proceedings of the National Academy of Sciences. 84:7915-7919
Pulmonary surfactant is a lipid-protein complex that promotes alveolar stability by lowering the surface tension at the air-fluid interface in the peripheral air spaces. A group of hydrophobic surfactant-associated proteins has been shown to be essen
Publikováno v:
Biochemical and Biophysical Research Communications. 149:1214-1219
In this study we have confirmed the presence of a single base difference between intestinal mRNA coding for B-48 and hepatic mRNA coding for B-100, which results in the substitution of a stop codon (UAA) for a glutamine codon (CAA) at a point corresp
Autor:
Miles Yamanaka, Richard S. Nishioka, Jeffrey J. Seilhamer, Norman L. Eberhardt, Gregg L. Mayer, Lorin K. Johnson, Charles S. Nicoll, Judy Miller, John D. Baxter, Susan Steiny, David S. King, James W. Schilling
Publikováno v:
General and Comparative Endocrinology. 68:387-399
Total RNA was extracted from coho salmon growth hormone (sGH) cell regions and used to synthesize double-stranded cDNA, which was inserted into a plasmid vector and used to transform Escherichia coli HB101. The total RNA was also separated according
Autor:
Tracey Crisp, Kenneth K. Lau, John C. Fiddes, Maria Elena Silva, James W. Schilling, Denis Gospodarowicz, Richard Mitchell, Judith A. Abraham, Edmund Tischer
Publikováno v:
Biochemical and Biophysical Research Communications. 165:1198-1206
Using applications of the polymerase chain reaction (PCR) technique, cDNA clones have been isolated encoding bovine vascular endothelial growth factor (VEGF), a mitogen with specificity for vascular endothelial cells. Analysis of the clones indicates