Výsledky vyhledávání - "James W. Salter"

Molecular determinants of the prothrombogenic phenotype assumed by inflamed colonic venules

Autor: Mikiji Mori, Karen Y. Stokes, James W. Salter, Thorsten Vowinkel, D. Neil Granger, Christian F. Krieglstein

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G920-G926

Although platelets have been implicated in the pathogenesis of human inflammatory bowel diseases, little is known about the magnitude of platelet accumulation in the inflamed bowel, what regulates this process, and its relevance to the overall inflam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23daa49f534f11f4c51b73fbaefa0f1d
https://doi.org/10.1152/ajpgi.00371.2004

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Molecular Determinants of the Prothrombogenic and Inflammatory Phenotype Assumed by the Postischemic Cerebral Microcirculation

Autor: Janice Russell, Anil Nanda, James W. Salter, Dianne Cooper, John H. Zhang, Mami Ishikawa, D. Neil Granger

Publikováno v: Stroke. 34:1777-1782

Background and Purpose— Circulating blood cells have been implicated in the pathogenesis of cerebral ischemia/reperfusion (I/R) injury and stroke. The objective of this study was to define the magnitude and molecular determinants of the platelet- a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98476a1500408ce31b4055c26f200126
https://doi.org/10.1161/01.str.0000074921.17767.f2

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Regulation of Murine Intestinal Inflammation by Reactive Metabolites of Oxygen and Nitrogen

Autor: D. Neil Granger, Christopher R. Ross, Janice Russell, James W. Salter, F. Stephen Laroux, Wolfgang H. Cerwinka, Guido Schuermann, Christian F. Krieglstein, Matthew B. Grisham

Publikováno v: Journal of Experimental Medicine. 194:1207-1218

Several reports have implicated reactive oxygen and nitrogen metabolites (RONS) in the initiation and/or progression of inflammatory bowel diseases (IBDs). We have investigated the role of three key RONS-metabolizing enzymes (inducible nitric oxide s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa25e326626803886e7eb5101e42df39
https://doi.org/10.1084/jem.194.9.1207

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Role of Intercellular Adhesion Molecule 1 in Indomethacin-Induced Ileitis

Autor: James W. Salter, Guido Schuermann, D. Neil Granger, Matthew B. Grisham, Janice Russell, Christian F. Krieglstein, Matthias Bruewer, F. Stephen Laroux, Wolfgang H. Cerwinka

Publikováno v: Biochemical and Biophysical Research Communications. 282:635-642

Adhesion molecules have been implicated in the pathogenesis of inflammatory bowel diseases. We investigated their expression and contribution to leukocyte recruitment in experimental intestinal inflammation. Ileitis was induced in Sprague-Dawley rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37212029f987c69d1576654e451ca015
https://doi.org/10.1006/bbrc.2001.4609

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Molecular Determinants of Dextran Sodium Sulfate Colitis-Induced Platelet Adhesion in Colonic Venules

Autor: James W. Salter, Mikiji Mori, Thorsten Vowinkel, D. Neil Granger

Publikováno v: Organ Microcirculation ISBN: 4431221352

Platelets have been implicated in the pathogenesis of human inflammatory bowel diseases (IBD). Animal experimentation has recently focused on defining the magnitude and mechanism of platelet accumulation in the inflamed bowel. We have previously show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cec2c8610cf91cf67a083cfd4bd7d3c
https://doi.org/10.1007/4-431-27174-0_36

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Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion

Autor: D. Neil Granger, Thiruma V. Arumugam, James W. Salter, Christie M. Ballantyne, Christopher G. Kevil, John H. Chidlow

Publikováno v: American journal of physiology. Heart and circulatory physiology. 287(6)

Although the β2-integrins have been implicated in the pathogenesis of cerebral ischemia-reperfusion (I/R) injury, the relative contributions of the α-subunits to the pathogenesis of ischemic stroke remains unclear. The objective of this study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8ba4138cd4e92e35a6e52e74fe8e28
https://pubmed.ncbi.nlm.nih.gov/15308480

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Platelets modulate ischemia/reperfusion-induced leukocyte recruitment in the mesenteric circulation

Autor: D. Neil Granger, Andrew C. Issekutz, James W. Salter, Christian F. Krieglstein

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology. 281(6)

P-selectin-dependent leukocyte-endothelial cell adhesion has been implicated in the pathogenesis of ischemia/reperfusion (I/R) injury in several vascular beds, including the gut. Because platelet-endothelial (P/E) cell adhesion also occurs in postisc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4a71a3117a27d693493a8240ef3afa
https://pubmed.ncbi.nlm.nih.gov/11705748

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