Zobrazeno 1 - 10
of 24
pro vyhledávání: '"James W. Gillespie"'
Publikováno v:
Viruses, Vol 14, Iss 2, p 384 (2022)
The evolution of the SARS-CoV-2 virus during the COVID-19 pandemic was accompanied by the emergence of new heavily mutated viral variants with increased infectivity and/or resistance to detection by the human immune system. To respond to the urgent n
Externí odkaz:
https://doaj.org/article/87adce2914cf4afda31ba8a80de278e7
Autor:
James W. Gillespie, Liping Yang, Laura Maria De Plano, Murray A. Stackhouse, Valery A. Petrenko
Publikováno v:
Viruses, Vol 11, Iss 11, p 988 (2019)
Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-d
Externí odkaz:
https://doaj.org/article/ea99edf4cb524b73bc8f90b0badd9d38
Publikováno v:
Viruses, Vol 11, Iss 9, p 785 (2019)
Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targetin
Externí odkaz:
https://doaj.org/article/59753f8b8fbe4703af04549d34c10e5a
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Active tumor targeting of nanomedicines has recently shown significant improvements in the therapeutic activity of currently existing drug delivery systems, such as liposomal doxorubicin (Doxil/Caelyx/Lipodox). Previously, we have shown that isolated
Externí odkaz:
https://doaj.org/article/37d38e1312b442c5a080a1e62eac9cb3
Autor:
Tao Wang, Huilan Ren, Radhika Narayanaswamy, Vladimir P. Torchilin, James W. Gillespie, Valery A. Petrenko
Publikováno v:
Journal of Drug Targeting. 26:505-515
Pancreatic cancer has been a life-threatening illness associated with high incidence and mortality rates. Paclitaxel that causes mitotic arrest in cancer cells disrupting microtubule function is used for pancreatic cancer treatment[1]. Nausea, anorex
Publikováno v:
Viruses
Volume 11
Issue 11
Viruses, Vol 11, Iss 11, p 988 (2019)
Volume 11
Issue 11
Viruses, Vol 11, Iss 11, p 988 (2019)
Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-d
Autor:
James W. Gillespie, Valery A. Petrenko
Publikováno v:
Expert Opinion on Drug Delivery. 14:373-384
New phage-directed nanomedicines have emerged recently as a result of the in-depth study of the genetics and structure of filamentous phage and evolution of phage display and phage nanobiotechnology. This review focuses on the progress made in the de
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 19:412-422
Cancer cell-specific diagnostic or therapeutic tools are commonly believed to significantly increase the success rate of cancer diagnosis and targeted therapies. To extend the repertoire of available cancer cell-specific phage fusion proteins and stu
Publikováno v:
Viruses, Vol 11, Iss 9, p 785 (2019)
Viruses
Volume 11
Issue 9
Viruses
Volume 11
Issue 9
Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targetin
Autor:
James W. Gillespie, Valery A. Petrenko
Publikováno v:
Journal of Vaccines & Vaccination.