Zobrazeno 1 - 10
of 81
pro vyhledávání: '"James W. Fristrom"'
Autor:
James W. Fristrom, Ann S. Hammonds
Publikováno v:
Genetics. 172:1577-1593
The Stubble-stubbloid (Sb-sbd) gene is required for ecdysone-regulated epithelial morphogenesis of imaginal tissues during Drosophila metamorphosis. Mutations in Sb-sbd are associated with defects in apical cell shape changes critical for the evagina
Autor:
Robert A. H. White, James W. Fristrom, Mary Prout, Stephen L. Gregory, Wayne L. Rickoll, Liselotte I. Fessler, Nicholas H. Brown
Publikováno v:
Developmental Cell. 3(4):569-579
We show that the Drosophila gene rhea , isolated because its wing blister phenotype is typical of mutants affecting integrin function, encodes talin. Embryos deficient in talin have very similar phenotypes to integrin (βPS) null embryos, including f
Publikováno v:
Developmental Biology. 181:168-185
The Broad-Complex, a 20-hydroxyecdysone-regulated gene, is essential for the development of many tissues during metamorphosis. In Broad-Complex mutants of the rbp complementation group, dorsoventral indirect flight muscles (DVM) are largely absent, a
Autor:
James W. Fristrom, Robin Abu-Shumays
Publikováno v:
Developmental Genetics. 20:11-22
IMP-L3, a gene isolated as a potential mediator of imaginal disc morphogenesis in Drosophila melanogaster, encodes lactate dehydrogenase (LDH). The predicted amino acid sequence of IMP-L3 is 58-61% identical to those of human LDHs. In cultured imagin
Publikováno v:
Developmental Biology. 177(1):1-14
The Broad-Complex (BR-C) is a key member of the 20-hydroxyecdysone regulatory hierarchy that coordinates changes in gene expression during Drosophila metamorphosis. The family of transcription factors encoded by the BR-C share a common amino-terminal
Publikováno v:
BioEssays. 17:693-702
Epithelial development dictates the shape of an organism. The metamorphic development of a Drosophila leg precursor into an adult leg is a well-defined example of epithelial morphogenesis that can be analyzed from the perspectives of genetics and mol
Autor:
Dianne Fristrom, Thomas B. Kornberg, Ethan Bier, James W. Fristrom, M. Sturtevant, Suzanne Eaton, P. Gotwals
Publikováno v:
Development. 120:2661-2671
We have characterized the blistered (bs) locus phenotypically, genetically and developmentally using a set of new bs alleles. Mutant defects range from wings with ectopic veins and intervein blisters to completely ballooned wings where the distinctio
Publikováno v:
Development. 119:1237-1250
The Drosophila IMP-L2 gene was identified as a 20hydroxyecdysone-induced gene encoding a membranebound polysomal transcript. IMP-L2 is an apparent secreted member of the immunoglobulin superfamily. We have used deficiencies that remove the IMP-L2 gen
Autor:
R.T. Apple, James W. Fristrom
Publikováno v:
Developmental Biology. 146:569-582
Transcripts of ecdysone-dependent genes (EDGs) accumulate in isolated imaginal discs within 8 hr after exposure to a pulse of the steroid hormone 20-hydroxyecdysone (20-HE; 1 μg/ml for 6 hr) but not in discs cultured in the continuous presence or ab
Autor:
P J Gotwals, James W. Fristrom
Publikováno v:
Genetics. 127:747-759
The Broad-Complex (BR-C) is a complex regulatory locus at 2B-5 on the X chromosome of Drosophila melanogaster. The wild-type BR-C products are apparent transcription factors necessary for imaginal disc morphogenesis. Alleles of the Stubble-stubbloid