Zobrazeno 1 - 10
of 29
pro vyhledávání: '"James W. Foster"'
Autor:
Céline Portal, Yvonne Lin, Varuni Rastogi, Cornelia Peterson, Samuel Chi-Hung Yiu, James W. Foster, Amber Wilkerson, Igor A. Butovich, Carlo Iomini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Meibomian gland (MG) cells are ciliated in early stages of development and primary cilium is required to regulate early MG cell patterning within developing glands, with cilia-mediated signaling pathways identified as therapeutic targets.
Externí odkaz:
https://doaj.org/article/1c246975864b4059b4eaf087504751f5
Autor:
Hyeck-Soo Son, Albert S. Jun, James W. Foster, Wei Wang, Yassine Daoud, Gerd U. Auffarth, Madhuparna Roy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract This study aimed to evaluate the efficacy of in situ adeno-associated virus (AAV)-mediated gene delivery into the human corneal limbal region via targeted sub-limbal injection technique. Human cadaveric corneal tissues were fixed on an artif
Externí odkaz:
https://doaj.org/article/8a67638419a64c2da2b58066ec2f0519
Publikováno v:
Journal of Ophthalmology, Vol 2020 (2020)
Purpose. This study aims to correlate the clinical signs of keratoconus (KC) which include superficial apical scarring, Fleischer rings, and Vogt striae with best spectacle-corrected visual acuity (BSCVA) and corneal tomography findings. Patients and
Externí odkaz:
https://doaj.org/article/7fa418a1df7e485e943aaa9e41052cf5
Autor:
George Maiti, Maithê Rocha Monteiro de Barros, Nan Hu, Igor Dolgalev, Mona Roshan, James W Foster, Aristotelis Tsirigos, Karl J Wahlin, Shukti Chakravarti
Publikováno v:
PNAS Nexus. 1
The cornea is a protective and refractive barrier in the eye crucial for vision. Understanding the human cornea in health, disease, and cell-based treatments can be greatly advanced with cornea organoids developed in culture from induced pluripotent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5175e7e4d6f044a232e1e280cfebc8fd
https://doi.org/10.1093/pnasnexus/pgac246
https://doi.org/10.1093/pnasnexus/pgac246
Publikováno v:
Curr Eye Res
The Integrated Stress Response (ISR) is a powerful and conserved signaling pathway that allows for cells to respond to a diverse array of both intracellular and extracellular stressors. The pathway is classically responsible for coordination of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fab38930a09fa5d29e8f5638aa73fd
https://doi.org/10.1080/02713683.2020.1867748
https://doi.org/10.1080/02713683.2020.1867748
Publikováno v:
Journal of Ophthalmology
Journal of Ophthalmology, Vol 2020 (2020)
Journal of Ophthalmology, Vol 2020 (2020)
Purpose. This study aims to correlate the clinical signs of keratoconus (KC) which include superficial apical scarring, Fleischer rings, and Vogt striae with best spectacle-corrected visual acuity (BSCVA) and corneal tomography findings.Patients and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a581c9083fe7d5cbac12ff69b1753ef3
http://europepmc.org/articles/PMC7048941
http://europepmc.org/articles/PMC7048941
Publikováno v:
Methods in Molecular Biology ISBN: 9781071605981
Methods Mol Biol
Methods Mol Biol
The cornea is the outermost transparent and refractive barrier surface of the eye necessary for vision. Development of the cornea involves the coordinated production of extracellular matrix, epithelial differentiation, and endothelial cell expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4e7de873e9be64cfa84700a8cb7714
https://doi.org/10.1007/978-1-0716-0599-8_5
https://doi.org/10.1007/978-1-0716-0599-8_5
Publikováno v:
Exp Eye Res
Keratoconus (KC), a progressive, degenerative corneal disease, represents the second leading indication for corneal transplantation globally. We have previously demonstrated that components of the Integrated Stress Response (ISR) are upregulated in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5117c72e658abac95344371f0d81c50a
https://doi.org/10.1016/j.exer.2021.108722
https://doi.org/10.1016/j.exer.2021.108722
Publikováno v:
The Open Ophthalmology Journal
Keratoconus is a common corneal ectasia that leads to progressive visual impairment. Numerous studies have shown abnormal protein expression patterns in keratoconic corneas. However, the specific mechanisms causing this disease remain ambiguous. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8300b99fafb8390cf93e0dd9613dd6b
http://europepmc.org/articles/PMC5585454
http://europepmc.org/articles/PMC5585454
Autor:
Mario Matthaei, Shukti Chakravarti, Albert S. Jun, Rupin N. Parikh, Kraig S. Bower, James W Foster, Charles G. Eberhart, Uri Soiberman, Jiangxia Wang
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose To identify global gene expression changes in the corneal epithelium of keratoconus (KC) patients compared to non-KC myopic controls. Methods RNA-sequencing was performed on corneal epithelium samples of five progressive KC and five myopic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066d2457a2a3e1eea61ebc1fc427151a
https://doi.org/10.1167/iovs.62.6.16
https://doi.org/10.1167/iovs.62.6.16