Zobrazeno 1 - 10
of 180
pro vyhledávání: '"James W Rocco"'
Autor:
Matthew Johnson, Jameel Muzaffar, Xuefeng Wang, Christine H Chung, Jose R Conejo-Garcia, Michael J Schell, Kedar Kirtane, Priyanka Bhateja, Marcelo Bonomi, Feifei Song, Jiannong Li, Sean J Yoder, Jose A Guevara-Patino, James W Rocco, Conor E Steuer, Nabil F Saba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/5c07de39e3c8402aa41c38e7422c0643
Publikováno v:
PLoS Medicine, Vol 12, Iss 2, p e1001786 (2015)
BackgroundAlthough the involvement of intra-tumor genetic heterogeneity in tumor progression, treatment resistance, and metastasis is established, genetic heterogeneity is seldom examined in clinical trials or practice. Many studies of heterogeneity
Externí odkaz:
https://doaj.org/article/c88cd379b7d744a1997a5d494a8860ac
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Autor:
Erick J Morris, William A Michaud, Jun-Yuan Ji, Nam-Sung Moon, James W Rocco, Nicholas J Dyson
Publikováno v:
PLoS Genetics, Vol 2, Iss 11, p e196 (2006)
Retinoblastoma protein and E2-promoter binding factor (E2F) family members are important regulators of G1-S phase progression. Deregulated E2F also sensitizes cells to apoptosis, but this aspect of E2F function is poorly understood. Studies of E2F-in
Externí odkaz:
https://doaj.org/article/f6b3ca3b83df4cb794ea17597d5eefc7
Autor:
Ignaty Leshchiner, Edmund A. Mroz, Justin Cha, Daniel Rosebrock, Oliver Spiro, Juliana Bonilla-Velez, William C. Faquin, Armida Lefranc-Torres, Derrick T. Lin, William A. Michaud, Gad Getz, James W. Rocco
Publikováno v:
Nature Cancer. 4:550-563
Analysis of premalignant tissue has identified the typical order of somatic events leading to invasive tumors in several cancer types. For other cancers, premalignant tissue is unobtainable, leaving genetic progression unknown. Here, we demonstrate h
Autor:
Sidharth V. Puram, Michael Mints, Ananya Pal, Zongtai Qi, Ashley Reeb, Kyla Gelev, Thomas F. Barrett, Sophie Gerndt, Ping Liu, Anuraag S. Parikh, Salma Ramadan, Travis Law, Edmund A. Mroz, James W. Rocco, Doug Adkins, Wade L. Thorstad, Hiram A. Gay, Li Ding, Randal C. Paniello, Patrik Pipkorn, Ryan S. Jackson, Xiaowei Wang, Angela Mazul, Rebecca Chernock, Jose P. Zevallos, Jessica Silva-Fisher, Itay Tirosh
Publikováno v:
Nature Genetics. 55:640-650
Autor:
Ernest Duah, Nathan D. Seligson, Avinash K. Persaud, Quynh Dam, Navjot Pabla, James W. Rocco, Junan Li, Ming Poi
Publikováno v:
Molecular Carcinogenesis.
Autor:
Marcelo Bonomi, Nabil F. Saba, Michael J. Schell, James W. Rocco, Kedar Kirtane, Jameel Muzaffar, Julie A. Kish, Dong M. Shin, Joaquim M. Farinhas, Philip J. Stephens, Charlotte Kuperwasser, Sunil Kumar, Bruce M. Wenig, Helen Molina, Juan C. Hernandez-Prera, Feifei Song, Maria I. Poole, Jude Masannat, Matthew Johnson, Priyanka Bhateja, Conor E. Steuer, Jiannong Li, Christine H. Chung
Purpose:A phase II multi-institutional clinical trial was conducted to determine overall survival (OS) in patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) treated with a combination of cetuximab and nivolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228471a7da6400ba5eae079135c167d8
https://doi.org/10.1158/1078-0432.c.6532391.v1
https://doi.org/10.1158/1078-0432.c.6532391.v1
Autor:
Marcelo Bonomi, Nabil F. Saba, Michael J. Schell, James W. Rocco, Kedar Kirtane, Jameel Muzaffar, Julie A. Kish, Dong M. Shin, Joaquim M. Farinhas, Philip J. Stephens, Charlotte Kuperwasser, Sunil Kumar, Bruce M. Wenig, Helen Molina, Juan C. Hernandez-Prera, Feifei Song, Maria I. Poole, Jude Masannat, Matthew Johnson, Priyanka Bhateja, Conor E. Steuer, Jiannong Li, Christine H. Chung
Supplementary Figure from Phase II Multi-institutional Clinical Trial Result of Concurrent Cetuximab and Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586f92af58e5d9ed3482955ea46899d4
https://doi.org/10.1158/1078-0432.22486817
https://doi.org/10.1158/1078-0432.22486817
Autor:
James W. Rocco, Leif W. Ellisen, Paul M. Busse, Hiroshi Wada, William H. Westra, Shahnaz Begum, John R. Clark, William C. Faquin, Edmund A. Mroz, Anthony C. Nichols, William A. Michaud
Supplementary Figures S1-S3 from Bcl-2 Blocks Cisplatin-Induced Apoptosis and Predicts Poor Outcome Following Chemoradiation Treatment in Advanced Oropharyngeal Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab6632c2debd410a7651c7ddca63f6c
https://doi.org/10.1158/1078-0432.22439995
https://doi.org/10.1158/1078-0432.22439995