Zobrazeno 1 - 10
of 32
pro vyhledávání: '"James W Peacock"'
Autor:
James W Peacock, Ario Takeuchi, Norihiro Hayashi, Liangliang Liu, Kevin J Tam, Nader Al Nakouzi, Nastaran Khazamipour, Tabitha Tombe, Takashi Dejima, Kevin CK Lee, Masaki Shiota, Daksh Thaper, Wilson CW Lee, Daniel HF Hui, Hidetoshi Kuruma, Larissa Ivanova, Parvin Yenki, Ivy ZF Jiao, Shahram Khosravi, Alice L‐F Mui, Ladan Fazli, Amina Zoubeidi, Mads Daugaard, Martin E Gleave, Christopher J Ong
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 219-238 (2018)
Abstract Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathway
Externí odkaz:
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
Autor:
Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract FOXA1 is a pioneer transcription factor that is frequently mutated in prostate, breast, bladder, and salivary gland malignancies. Indeed, metastatic castration-resistant prostate cancer (mCRPC) commonly harbour FOXA1 mutations with a prevale
Externí odkaz:
https://doaj.org/article/04472dd65cc24c0c8a00dc7c0f4fd55c
Autor:
Satyam Bhasin, Christopher Dusek, James W. Peacock, Artem Cherkasov, Yuzhuo Wang, Martin Gleave, Christopher J. Ong
Publikováno v:
Cells, Vol 12, Iss 13, p 1715 (2023)
Estrogen receptor positive (ER+) breast cancer (BCa) accounts for the highest proportion of breast cancer-related deaths. While endocrine therapy is highly effective for this subpopulation, endocrine resistance remains a major challenge and the ident
Externí odkaz:
https://doaj.org/article/ce525f990ef941c8b21cdd5b891206db
Autor:
Ong, Satyam Bhasin, Christopher Dusek, James W. Peacock, Artem Cherkasov, Yuzhuo Wang, Martin Gleave, Christopher J.
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1715
Estrogen receptor positive (ER+) breast cancer (BCa) accounts for the highest proportion of breast cancer-related deaths. While endocrine therapy is highly effective for this subpopulation, endocrine resistance remains a major challenge and the ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9a457c5f4965962784d8ee4087b75e92
Autor:
Mani Roshan-Moniri, Franck Duong, Fuqiang Ban, Hélène Morin, Huifang Li, Kush Dalal, Paul S. Rennie, Christopher J. Ong, Eric Leblanc, Michael Carlson, Kevin J. Tam, Ashley Shepherd, Artem Cherkasov, James W. Peacock, Aishwariya Sharma, Carl Perez
Publikováno v:
Cancer Letters. 437:35-43
Prostate cancer (PCa) is a leading cause of death for men in North America. The androgen receptor (AR) - a hormone inducible transcription factor - drives expression of tumor promoting genes and represents an important therapeutic target in PCa. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f51f40d14929e696740fcff4229767d
https://doi.org/10.1016/j.canlet.2018.08.016
https://doi.org/10.1016/j.canlet.2018.08.016
Autor:
Amina Zoubeidi, Liangliang Liu, James W. Peacock, Kevin J. Tam, Shahram Khosravi, Kevin C.K. Lee, Norihiro Hayashi, Christopher J. Ong, Wilson C.W. Lee, Masaki Shiota, Takashi Dejima, Martin E. Gleave, Daniel H. F. Hui, Nader Al Nakouzi, Larissa Ivanova, Nastaran Khazamipour, Daksh Thaper, Hidetoshi Kuruma, Ladan Fazli, Tabitha Tombe, Parvin Yenki, Ivy Z. F. Jiao, Alice L.-F. Mui, Mads Daugaard, Ario Takeuchi
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 219-238 (2018)
EMBO Molecular Medicine
EMBO Molecular Medicine
Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cd212df39db9680a800250ee32a82f
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
Autor:
Chi Wing Cheng, Kush Dalal, Michael Hsing, Yan Ting Chiang, Yuzhuo Wang, Parvin Yenki, Kevin J. Tam, Artem Cherkasov, Aishwariya Sharma, Martin E. Gleave, Charan Tse, Paul S. Rennie, Shahram Khosravi, Christopher J. Ong, James W. Peacock
Publikováno v:
Oncotarget
// Kevin J. Tam 1, 2 , Kush Dalal 1 , Michael Hsing 1 , Chi Wing Cheng 1 , Shahram Khosravi 1 , Parvin Yenki 1, 2 , Charan Tse 1 , James W. Peacock 1, 2 , Aishwariya Sharma 1 , Yan Ting Chiang 1, 3 , Yuzhuo Wang 1, 3, 4 , Artem Cherkasov 1, 4 , Paul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdd2dbb22f934532e61a36c934418ec
http://europepmc.org/articles/PMC5354758
http://europepmc.org/articles/PMC5354758
Autor:
Kevin J. Tam, Yifan Gong, Benjamin Vanderkruk, Christopher J. Ong, Ivy Z. F. Jiao, Liangliang Liu, James W. Peacock, Luke Gooding, Kevin C.K. Lee, Artem Cherkasov, Chung C W Lee, Colin G Sedgwick, Ashley Shepherd, Kush Dalal, Tabitha Tombe, Satyam Bhasin, Ravi Shashi Nayana Munuganti, Martin E. Gleave
Publikováno v:
Journal of the Endocrine Society
Despite the amenability of early-stage prostate cancer to surgery and radiation therapy, locally advanced and metastatic prostate cancer is clinically problematic. Chemical castration is often used as a first-line therapy for advanced disease, but pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eac988b5b731a34aafcdded4d448947
https://pubmed.ncbi.nlm.nih.gov/30534631
https://pubmed.ncbi.nlm.nih.gov/30534631
Autor:
Kevin J. Tam, Ralph Buttyan, James W. Peacock, Daniel H. F. Hui, Shahram Khosravi, Ario Takeuchi, Mingshu Dong, Ivy Z. F. Jiao, Michael E. Cox, Wilson W. Lee, Christopher J. Ong, Tabitha Tombe, Martin E. Gleave, Larissa Ivanova, Igor Moskalev
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Prostate cancer (PCa) is among the most commonly-occurring cancers worldwide and a leader in cancer-related deaths. Local non-invasive PCa is highly treatable but limited treatment options exist for those with locally-advanced and metastatic forms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e221f92b51e699bc679110f35be3f4d
http://europepmc.org/articles/PMC5597577
http://europepmc.org/articles/PMC5597577
Autor:
Xavier Alvarez Hernandez, Cecily C. Midkiff, Sallie R. Permar, Holly Heimsath, James W. Peacock, Jonathon E. Himes, Faith Schiro, Nathan Vandergrift, Celia C. LaBranche, Pyone P. Aye, Ria Goswami, Joshua Eudailey, Riley J. Mangan, Quang N. Nguyen, Guido Ferrari, David C. Montefiori, Meng Chen, Thomas Lee Jeffries, Justin Pollara, Amit Kumar
Publikováno v:
Mucosal immunology
Vertical HIV-1 transmission via breastfeeding is the predominant contributor to pediatric infections that are ongoing in this era of highly effective antiretroviral therapy (ART). Remarkably, only ~10% of infants chronically exposed to the virus via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c53b89bb78e8da48d701572a0028a56
https://doi.org/10.1101/145524
https://doi.org/10.1101/145524
