Zobrazeno 1 - 10
of 143
pro vyhledávání: '"James W Grau"'
Autor:
Christopher Nelson Hansen, Timothy Dale Faw, John A. Buford, Susan eWhite, James W Grau, D. Michele eBasso
Publikováno v:
Frontiers in Neural Circuits, Vol 10 (2016)
This study evaluated the role of spared axons on structural and behavioral neuroplasticity in the lumbar enlargement after a thoracic spinal cord injury (SCI). Previous work has demonstrated that recovery in the presence of spared axons after an inco
Externí odkaz:
https://doaj.org/article/1ae2e1306e0a4c84b06d83f77bd37306
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
How a stimulus impacts spinal cord function depends upon temporal relations. When intermittent noxious stimulation (shock) is applied and the interval between shock pulses is varied (unpredictable), it induces a lasting alteration that inhibits adapt
Externí odkaz:
https://doaj.org/article/04034c382a574e72a28df005ad082e09
Autor:
Kuan H. Lee, Joel D Turtle, Misty Marie Strain, Yung-Jen eHuang, Kyle M. Baumbauer, James W Grau
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 9 (2015)
Prior studies have shown that intermittent noxious stimulation has divergent effects on spinal cord plasticity depending upon whether it occurs in a regular [fixed time (FT)] or irregular [variable time (VT)] manner: In spinally transected animals, V
Externí odkaz:
https://doaj.org/article/c11cc6a72c2b482d977ba650b17b3a57
Autor:
Eric R Strickland, Sarah A Woller, Sandra M Garraway, Michelle A Hook, James W Grau, Rajesh C Miranda
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Uncontrollable nociceptive stimulation adversely affects recovery in spinally contused rats. Spinal cord injury (SCI) results in altered microRNA (miRNA) expression both at, and distal to the lesion site. We hypothesized that uncontrollable nocicepti
Externí odkaz:
https://doaj.org/article/be32847e67494e7fb9798618be5cdc53
Autor:
James W Grau, J Russell Huie, Kuan H Lee, Kevin C Hoy, Yung-Jen eHuang, Joel D Turtle, Misty M. Strain, Kyle M Baumbauer, Rajesh M Miranda, Michelle A Hook, Adam R Ferguson, Sandra M. Garraway
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Research has shown that spinal circuits have the capacity to adapt in response to training, nociceptive stimulation and peripheral inflammation. These changes in neural function are mediated by physiological and neurochemical systems analogous to tho
Externí odkaz:
https://doaj.org/article/67b73a12a21b4d1fa0f3488e9e7d9fff
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation. Numerous papers have described centra
Externí odkaz:
https://doaj.org/article/c1a4b6e98f3f46948ba6a01a886808f1
Autor:
Adam R Ferguson, J Russell eHuie, Eric D Crown, Kyle M Baumbauer, Michelle A Hook, Sandra M Garraway, Kuan H Lee, Kevin C Hoy, James W Grau
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent manner even without input from the brain after complete SCI. T
Externí odkaz:
https://doaj.org/article/5ee50337a7f24eb192040b1b3c968f21
Autor:
James W Grau, Russell eHuie, Sandra M. Garraway, Michelle A. Hook, Eric D. Crown, Kyle M. Baumbauer, Kuan H. Lee, Kevin C. Hoy, Adam R Ferguson
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
How nociceptive signals are processed within the spinal cord, and whether these signals lead to behavioral signs of neuropathic pain, depends upon their relation to other events and behavior. Our work shows that these relations can have a lasting eff
Externí odkaz:
https://doaj.org/article/c33dd4934d824b7fae402c17305298a2
Autor:
J Russell Huie, Kyle M Baumbauer, Kuan H Lee, Jacqueline C Bresnahan, Michael S Beattie, Adam R Ferguson, James W Grau
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39751 (2012)
Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spin
Externí odkaz:
https://doaj.org/article/8637f9c83db44f659a2f124abfa0a268
Publikováno v:
Frontiers in Systems Neuroscience, Vol 18 (2024)
Those studying neural systems within the brain have historically assumed that lower-level processes in the spinal cord act in a mechanical manner, to relay afferent signals and execute motor commands. From this view, abstracting temporal and environm
Externí odkaz:
https://doaj.org/article/e9a8de79122a44c0b761f06236b294ea